Patents by Inventor Gustav Silfversparre

Gustav Silfversparre has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method for growth of bacteria, minimising the release of endotoxins from the bacteria into the surrounding medium
    Patent number: 7198936
    Abstract: The invention relates to a method for growth of bacteria, such as Gram negative bacteria and its corresponding supernatant. The bacteria are cultivated without substantial release of endotoxins from the bacteria into the surrounding medium. Thereby the need of purification steps necessary to remove endotoxins are reduced or eliminated such as when the bacteria are producing a product which later on should be administered to a mammal, such as a human. The bacteria are also cultivated without substantial formation of acetic acid. The level of the carbon/energy source is controled during the cultivation and oxygen limitation is avoided through regulation of the temperature. The method may be used for cultivation of bacterial in fermenters.
    Type: Grant
    Filed: October 30, 2001
    Date of Patent: April 3, 2007
    Assignee: Novozymes Biopharma AB
    Inventors: Gustav Silfversparre, Sven-Olof Enfors, Ling Han, Lena Häggström, Harald Skogman
  • Method for growth of bacteria, minimising the release of endotoxins from the bacteria into the surrounding medium
    Publication number: 20040029253
    Abstract: The invention relates to a method for growth of bacteria, such as Gram negative bacteria and its corresponding supernatant. The bacteria are cultivated without substantial release of endotoxins from the bacteria into the surrounding medium. Thereby the need of purification steps necessary to remove endotoxins are reduced or eliminated such as when the bacteria are producing a product which later on should be administered to a mammal, such as a human. The bacteria are also cultivated without substantial formation of acetic acid. The level of the carbon/energy source is controled during the cultivation and oxygen limitation is avoided through regulation of the temperature. The method may be used for cultivation of bacterial in fermenters.
    Type: Application
    Filed: August 13, 2003
    Publication date: February 12, 2004
    Inventors: Gustav Silfversparre, Sven-Olof Enfors, Ling Han, Lena Haggstrom, Harald Skogman