Patents by Inventor Guy Kol

Guy Kol has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 7906635
    Abstract: Novel markers for ovarian cancer that are both sensitive and accurate. These markers are overexpressed and/or differentially expressed in ovarian cancer specifically, as opposed to normal ovarian tissue. The measurement of these markers, alone or in combination, in patient samples provides information that the diagnostician can correlate with a probable diagnosis, in ovarian cancer. The markers of the present invention, alone or in combination, show a high degree of differential detection between ovarian cancer and non-cancerous states.
    Type: Grant
    Filed: January 15, 2009
    Date of Patent: March 15, 2011
    Assignee: Compugen Ltd.
    Inventors: Gad S. Cojocaru, Sarah Pollock, Zurit Levine, Alexander Diber, Guy Kol, Amir Toporik, Rotem Sorek, Dvir Dahary, Michal Ayalon-Soffer, Pinchas Akiva, Amit Novik, Yossi Cohen, Osnat Sella-Tavor, Shira Walach, Shirley Sameah-Greenwald, Ronen Shemesh, Maxim Shklar
  • Patent number: 7842459
    Abstract: Novel splice variant nucleic acid sequences. The novel splice variants and their nucleic acid sequences according to the present invention may optionally be used for diagnosis of a variant-detectable disease as described herein.
    Type: Grant
    Filed: January 27, 2005
    Date of Patent: November 30, 2010
    Assignee: Compugen Ltd.
    Inventors: Michal Ayalon-Soffer, Sarah Pollock, Ronen Shemesh, Rotem Sorek, Zurit Levine, Zipi Shaqed, Amir Toporik, Gad S. Cojocaru, Dvir Dahary, Guy Kol, Pinchas Akiva, Amit Novik, Sergey Nemzer, Alexander Diber, Maxim Shklar, Osnat Sella-Tavor, Lily Bazak, Ariel Farkash, Yossi Cohen
  • Publication number: 20100248270
    Abstract: Novel markers for cardiac disease that are both sensitive and accurate. These markers are differentially and/or specifically expressed in cardiac tissue, as opposed to other types of tissues, optionally and preferably including muscle tissue. The measurement of these markers, alone or in combination, in patient samples provides information that the diagnostician can correlate with a probable diagnosis of cardiac disease, including pathology and/or damage, including acute and/or chronic damage. The markers of the present invention, alone or in combination, show a high degree of differential detection between cardiac disease states and non-cardiac disease states.
    Type: Application
    Filed: November 23, 2009
    Publication date: September 30, 2010
    Applicant: Compugen Ltd
    Inventors: Yossi Cohen, Alexander Diber, Amir Toporik, Sarah Pollock, Zurit Levine, Michal Ayalon-Soffer, Gad S. Cojocaru, Amit Novik, Guy Kol, Osnat Sella-Tavor, Shira Walach, Shirley Sameah-Greenwald, Dvir Dahary, Ronen Shemesh
  • Publication number: 20100124786
    Abstract: Novel markers for ovarian cancer that are both sensitive and accurate. These markers are overexpressed and/or differentially expressed in ovarian cancer specifically, as opposed to normal ovarian tissue. The measurement of these markers, alone or in combination, in patient samples provides information that the diagnostician can correlate with a probable diagnosis, in ovarian cancer. The markers of the present invention, alone or in combination, show a high degree of differential detection between ovarian cancer and non-cancerous states.
    Type: Application
    Filed: January 15, 2009
    Publication date: May 20, 2010
    Applicant: Compugen LTD
    Inventors: Gad S. Cojocaru, Sarah Pollock, Zurit Levine, Alexander Diber, Guy Kol, Amir Toporik, Rotem Sorek, Dvir Dahary, Michal Ayalon-Soffer, Pinchas Akiva, Amit Novik, Yossi Cohen, Osnat Sella-Tavor, Shira Walach, Shirley Sameah-Greenwald, Ronen Shemesh, Maxim Shklar
  • Publication number: 20100120022
    Abstract: Novel splice variant nucleic acid sequences. The novel splice variants and their nucleic acid sequences according to the present invention may optionally be used for diagnosis of a variant-detectable disease as described herein.
    Type: Application
    Filed: January 27, 2005
    Publication date: May 13, 2010
    Inventors: Michal Ayalon-Soffer, Sarah Pollock, Ronen Shemesh, Rotem Sorek, Zurit Levine, Zipi Shaqed, Amir Toporik, Gad S. Cojocaru, Dvir Dahary, Guy Kol, Pinchas Akiva, Amit Novik, Sergey Nemzer, Alexander Diber, Maxim Shklar, Osnat Sella-Tavor, Lily Bazak, Ariel Farkash, Yossi Cohen
  • Patent number: 7714100
    Abstract: Novel markers for cardiac disease that are both sensitive and accurate. These markers are differentially and/or specifically expressed in cardiac tissue, as opposed to other types of tissues, optionally and preferably including muscle tissue. The measurement of these markers, alone or in combination, in patient samples provides information that the diagnostician can correlate with a probable diagnosis of cardiac disease, including pathology and/or damage, including acute and/or chronic damage. The markers of the present invention, alone or in combination, show a high degree of differential detection between cardiac disease states and non-cardiac disease states.
    Type: Grant
    Filed: October 29, 2007
    Date of Patent: May 11, 2010
    Assignee: Compugen LTD
    Inventors: Yossi Cohen, Alexander Diber, Amir Toporik, Sarah Pollock, Zurit Levine, Michal Ayalon-Soffer, Gad S. Cojocaru, Amit Novik, Guy Kol, Osnat Sella-Tavor, Shira Walach, Shirley Sameah-Greenwald, Dvir Dahary, Ronen Shemesh
  • Publication number: 20090215046
    Abstract: Novel markers for colon cancer that are both sensitive and accurate. These markers are overexpressed in colon cancer specifically, as opposed to normal colon tissue. The measurement of these markers, alone or in combination, in patient samples provides information that the diagnostician can correlate with a probable diagnosis of colon cancer. The markers of the present invention, alone or in combination, show a high degree of differential detection between colon cancer and non-cancerous states.
    Type: Application
    Filed: October 23, 2007
    Publication date: August 27, 2009
    Applicant: COMPUGEN LTD.
    Inventors: Rotem Sorek, Michal Ayalon-Soffer, Dvir Dahary, Amit Novik, Amir Toporik, Alexander Diber, Guy Kol, Sarah Pollock, Zurit Levine, Gad S. Cojocaru, Ronen Shemesh, Yossi Cohen, Osnat Sella-Tavor, Shirley Sameah-Greenwald, Shira Walach
  • Patent number: 7553948
    Abstract: Novel markers for ovarian cancer that are both sensitive and accurate. These markers are overexpressed and/or differentially expressed in ovarian cancer specifically, as opposed to normal ovarian tissue. The measurement of these markers, alone or in combination, in patient samples provides information that the diagnostician can correlate with a probable diagnosis, in ovarian cancer. The markers of the present invention, alone or in combination, show a high degree of differential detection between ovarian cancer and non-cancerous states.
    Type: Grant
    Filed: March 6, 2007
    Date of Patent: June 30, 2009
    Assignee: Compugen Ltd
    Inventors: Gad S. Cojocaru, Sarah Pollock, Zurit Levine, Alexander Diber, Guy Kol, Amir Toporik, Rotem Sorek, Dvir Dahary, Michal Ayalon-Soffer, Pinchas Akiva, Amit Novik, Yossi Cohen, Osnat Sella-Tavor, Shira Walach, Shirley Sameah-Greenwald, Ronen Shemesh, Maxim Shklar
  • Publication number: 20090004648
    Abstract: Novel markers for ovarian cancer that are both sensitive and accurate. These markers are overexpressed and/or differentially expressed in ovarian cancer specifically, as opposed to normal ovarian tissue. The measurement of these markers, alone or in combination, in patient samples provides information that the diagnostician can correlate with a probable diagnosis, in ovarian cancer. The markers of the present invention, alone or in combination, show a high degree of differential detection between ovarian cancer and non-cancerous states.
    Type: Application
    Filed: March 6, 2007
    Publication date: January 1, 2009
    Applicant: COMPUGEN LTD.
    Inventors: Gad S. Cojocaru, Sarah Pollock, Zurit Levine, Alexander Diber, Guy Kol, Amir Toporik, Rotem Sorek, Dvir Dahary, Michal Ayalon-Soffer, Pinchas Akiva, Amit Novik, Yossi Cohen, Osnat Sella-Tavor, Shira Walach, Shirley Sameah-Greenwald, Ronen Shemesh, Maxim Shklar
  • Publication number: 20080193941
    Abstract: Novel markers for cardiac disease that are both sensitive and accurate. These markers are differentially and/or specifically expressed in cardiac tissue, as opposed to other types of tissues, optionally and preferably including muscle tissue. The measurement of these markers, alone or in combination, in patient samples provides information that the diagnostician can correlate with a probable diagnosis of cardiac disease, including pathology and/or damage, including acute and/or chronic damage. The markers of the present invention, alone or in combination, show a high degree of differential detection between cardiac disease states and non-cardiac disease states.
    Type: Application
    Filed: October 29, 2007
    Publication date: August 14, 2008
    Applicant: COMPUGEN LTD.
    Inventors: Yossi Cohen, Alexander Diber, Amir Toporik, Sarah Pollock, Zurit Levine, Michal Avalon-Soffer, Gad S. Cojocaru, Amit Novik, Guy Kol, Osnat Sella-Tavor, Shira Walach, Shirley Sameah-Greenwald, Dvir Dahary, Ronen Shemesh
  • Patent number: 7345142
    Abstract: Novel markers for cardiac disease that are both sensitive and accurate. These markers are differentially and/or specifically expressed in cardiac tissue, as opposed to other types of tissues, optionally and preferably including muscle tissue. The measurement of these markers, alone or in combination, in patient samples provides information that the diagnostician can correlate with a probable diagnosis of cardiac disease, including pathology and/or damage, including acute and/or chronic damage. The markers of the present invention, alone or in combination, show a high degree of differential detection between cardiac disease states and non-cardiac disease states.
    Type: Grant
    Filed: January 27, 2005
    Date of Patent: March 18, 2008
    Assignee: Compugen Ltd.
    Inventors: Yossi Cohen, Alexander Diber, Amir Toporik, Sarah Pollock, Zurit Levine, Michal Ayalon-Soffer, Gad S. Cojocaru, Amit Novik, Guy Kol, Osnat Sella-Tavor, Shira Walach, Shirley Sameah-Greenwald, Dvir Dahary, Ronen Shemesh
  • Publication number: 20070082337
    Abstract: A method of identifying alternatively spliced exons is provided. The method comprising, scoring each of a plurality of exon sequences derived from genes of a species according to at least one sequence parameter, wherein exon sequences of the plurality of exon sequences scoring above a predetermined threshold represent alternatively spliced exons, thereby identifying the alternatively spliced exons.
    Type: Application
    Filed: January 27, 2005
    Publication date: April 12, 2007
    Applicant: Compugen Ltd.
    Inventors: Rotem Sorek, Sarah Pollock, Alex Diber, Zurit Levine, Sergey Nemzer, Guy Kol, Assaf Wool, Ami Haviv, Yuval Cohen, Yossi Cohen, Ronen Shemesh, Kinneret Savitsky
  • Publication number: 20060263786
    Abstract: Novel markers for colon cancer that are both sensitive and accurate. These markers are overexpressed in colon cancer specifically, as opposed to normal colon tissue. The measurement of these markers, alone or in combination, in patient samples provides information that the diagnostician can correlate with a probable diagnosis of colon cancer. The markers of the present invention, alone or in combination, show a high degree of differential detection between colon cancer and non-cancerous states.
    Type: Application
    Filed: January 27, 2005
    Publication date: November 23, 2006
    Inventors: Rotem Sorek, Michal Ayalon-Soffer, Dvir Dahary, Amit Novik, Amir Toporik, Alexander Diber, Guy Kol, Sarah Pollock, Zurit Levine, Gad Coiocaru, Ronen Shemesh, Yossi Cohen, Osnat Sella-Tavor, Shirley Sameah-Greenwald, Shira Walach
  • Publication number: 20060172311
    Abstract: Novel markers for cardiac disease that are both sensitive and accurate. These markers are differentially and/or specifically expressed in cardiac tissue, as opposed to other types of tissues, optionally and preferably including muscle tissue. The measurement of these markers, alone or in combination, in patient samples provides information that the diagnostician can correlate with a probable diagnosis of cardiac disease, including pathology and/or damage, including acute and/or chronic damage. The markers of the present invention, alone or in combination, show a high degree of differential detection between cardiac disease states and non-cardiac disease states.
    Type: Application
    Filed: January 27, 2005
    Publication date: August 3, 2006
    Inventors: Yossi Cohen, Alexander Diber, Amir Toporik, Sarah Pollock, Zurit Levine, Michal Ayalon-Soffer, Gad Cojocaru, Amit Novik, Guy Kol, Osnat Sella-Tavor, Shira Walach, Shirley Sameah-Greenwald, Dvir Dahary, Ronen Shemesh
  • Publication number: 20060040278
    Abstract: Novel markers for ovarian cancer that are both sensitive and accurate. These markers are overexpressed and/or differentially expressed in ovarian cancer specifically, as opposed to normal ovarian tissue. The measurement of these markers, alone or in combination, in patient samples provides information that the diagnostician can correlate with a probable diagnosis, in ovarian cancer. The markers of the present invention, alone or in combination, show a high degree of differential detection between ovarian cancer and non-cancerous states.
    Type: Application
    Filed: January 27, 2005
    Publication date: February 23, 2006
    Inventors: Gad Cojocaru, Sarah Pollock, Zurit Levine, Alexander Diber, Guy Kol, Amir Toporik, Rotem Sorek, Dvir Dahary, Michal Ayalon-Soffer, Pinchas Akiva, Amit Novik, Yossi Cohen, Osnat Sella-Tavor, Shira Walach, Shirley Sameah-Greenwald, Ronen Shemesh, Maxim Shklar