Patents by Inventor Guy Serre

Guy Serre has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • POLYPEPTIDE EXPRESSED IN THE STRATUM CORNEUM AND USE THEREOF
    Publication number: 20230227503
    Abstract: Polypeptides belonging to the family of late proteins of the cornified envelope (LCE), fragments of the polypeptide, isolated nucleotide sequences encoding the polypeptides, and cosmetic and/or pharmaceutical compositions containing such polypeptides are described. The polypeptides have cosmetic and/or therapeutic use to reinforce the barrier function of the epidermis, prevent and/or treat the signs of skin dryness and prevent and/or treat disorders of the barrier function or the weakening of the epidermis.
    Type: Application
    Filed: September 20, 2022
    Publication date: July 20, 2023
    Inventors: Nathalie JONCA, Eve TOULZA, Gaelle SAINTIGNY, Guy SERRE, Marina WEBER VIVAT
  • APHERESIS COLUMN FOR TREATING RHEUMATOID ARTHRITIS
    Publication number: 20230125698
    Abstract: The present invention relates to an apheresis column loaded with a solid support comprising a composition comprising at least one peptide selected from the group consisting of: —the ?I7I-I85cit peptide of amino acid sequence VDIDIKIX1SCX2GSCS (SEQ ID NO: 8) wherein X1 and X2 each represent a citmllyl residue, —the ?62I-635Cit peptide of amino acid sequence X1GHAKSX2PVX3GIHTS (SEQ ID NO: 12) wherein X1, X2 and X3 each represent a citmllyl residue—the P60-74cit-NH2 peptide of amino acid sequence X1PAPPPISGGGYX2AX3 (SEQ ID NO: 15) wherein X1 and X2 each represent a citmllyl residue and X3 represents a citmllyl derivative with a carboxamide group and—the peptide, referred to as the Ac-a36-50crt peptide, having the amino acid sequence GPX1VVEX2HQSACKDS (SEQ ID NO: 6) wherein the residue G at the N-terminal is acetylated and wherein X1 and X2 each represent a citmllyl residue and/or the a36-50cit peptide of amino acid sequence GPX1VVEX2HQSACKDS (SEQ ID NO: 5) wherein X1 and X2 each represent a citmllyl residue.
    Type: Application
    Filed: March 25, 2021
    Publication date: April 27, 2023
    Applicants: UNIVERSITÉ PAUL SABATIER TOULOUSE III, CENTRE HOSPITALIER UNIVERSITAIRE DE TOULOUSE, INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE, ASSISTANCE PUBLIQUE-HOPITAUX DE MARSEILLE, UNIVERSITE D'AIX-MARSEILLE
    Inventors: Guy Serre, Géraldine Offer, Marianne Chabod, Mikael Pancarte, Jean Roudier, Nathalie Balandraud
  • Polypeptide expressed in the stratum corneum and use thereof
    Patent number: 11479580
    Abstract: Polypeptides belonging to the family of late proteins of the cornified envelope (LCE), fragments of the polypeptide, isolated nucleotide sequences encoding the polypeptides, and cosmetic and/or pharmaceutical compositions containing such polypeptides are described. The polypeptides have cosmetic and/or therapeutic use to reinforce the barrier function of the epidermis, prevent and/or treat the signs of skin dryness and prevent and/or treat disorders of the barrier function or the weakening of the epidermis.
    Type: Grant
    Filed: September 21, 2018
    Date of Patent: October 25, 2022
    Assignees: CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE—CNRS, UNIVERSITE PAUL SABATIER TOULOUSE III
    Inventors: Nathalie Jonca, Eve Toulza, Gaelle Saintigny, Guy Serre, Marina Weber Vivat
  • POLYPEPTIDE EXPRESSED IN THE STRATUM CORNEUM AND USE THEREOF
    Publication number: 20190010191
    Abstract: Polypeptides belonging to the family of late proteins of the cornified envelope (LCE), fragments of the polypeptide, isolated nucleotide sequences encoding the polypeptides, and cosmetic and/or pharmaceutical compositions containing such polypeptides are described. The polypeptides have cosmetic and/or therapeutic use to reinforce the barrier function of the epidermis, prevent and/or treat the signs of skin dryness and prevent and/or treat disorders of the barrier function or the weakening of the epidermis.
    Type: Application
    Filed: September 21, 2018
    Publication date: January 10, 2019
    Inventors: Nathalie JONCA, Eve TOULZA, Gaelle SAINTIGNY, Guy SERRE, Marina WEBER VIVAT
  • POLYPEPTIDE EXPRESSED IN THE STRATUM CORNEUM AND USE THEREOF
    Publication number: 20170260235
    Abstract: Polypeptides belonging to the family of late proteins of the cornified envelope (LCE), fragments of the polypeptide, isolated nucleotide sequences encoding the polypeptides, and cosmetic and/or pharmaceutical compositions containing such polypeptides are described. The polypeptides have cosmetic and/or therapeutic use to reinforce the barrier function of the epidermis, prevent and/or treat the signs of skin dryness and prevent and/or treat disorders of the barrier function or the weakening of the epidermis.
    Type: Application
    Filed: March 2, 2017
    Publication date: September 14, 2017
    Inventors: Nathalie JONCA, Eve TOULZA, Gaelle SAINTIGNY, Guy SERRE, Marina WEBER VIVAT
  • Polypeptide expressed in the stratum corneum and use thereof
    Patent number: 9617307
    Abstract: Polypeptides belonging to the family of late proteins of the cornified envelope (LCE), fragments of the polypeptide, isolated nucleotide sequences encoding the polypeptides, and cosmetic and/or pharmaceutical compositions containing such polypeptides are described. The polypeptides have cosmetic and/or therapeutic use to reinforce the barrier function of the epidermis, prevent and/or treat the signs of skin dryness and prevent and/or treat disorders of the barrier function or the weakening of the epidermis.
    Type: Grant
    Filed: June 11, 2015
    Date of Patent: April 11, 2017
    Assignees: UNIVERSITE PAUL SABATIER (TOULOUSE III), CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE
    Inventors: Nathalie Jonca, Eve Toulza, Gaelle Saintigny, Guy Serre, Marina Weber Vivat
  • Peptidyl arginine deiminase 1 and/or 3 activator compounds in the epidermis and uses thereof
    Patent number: 9566222
    Abstract: The present invention relates to the activation of peptidyl arginine deiminase (PADs) 1 and/or 3 in the epidermis by at least one active agent used alone or in combination, namely caffeine, acefylline and/or theobromine in a cosmetic and/or pharmaceutical composition. The present invention also relates to the use of the aforementioned active agents in cosmetics and/or therapeutics, alone or in combination, in order to improve the barrier functions of the epidermis, to prevent and/or treat symptoms related to dry skin or to improve and/or promote hydration of the keratinous layer. Finally, the invention relates to increasing the activity of PAD1 and/or PAD3 in the epidermis.
    Type: Grant
    Filed: April 11, 2012
    Date of Patent: February 14, 2017
    Assignee: PIERRE FABRE DERMO-COSMETIQUE
    Inventors: Hélène Duplan, Sylvie Daunes-Marion, Stéphane Poigny, Marie-Claire Mechin, Guy Serre, Michel Simon
  • Peptides modulating the activity of macrophages, useable for the treatment of rheumatoid arthritis
    Patent number: 9388226
    Abstract: The invention relates to citrulline peptides with anti-inflammatory properties. The invention also relates to an in vitro model for activation of macrophages, induced by immune complexes between specified IgG of rheumatoid arthritis and their citrulline targets.
    Type: Grant
    Filed: May 3, 2007
    Date of Patent: July 12, 2016
    Assignee: Universite Paul Sabatier
    Inventors: Cyril Clavel, Mireille Sebbag, Maria Leonor Nogueira, Guy Serre
  • Citrulline peptides derived from fibrin and recognized by rheumatoid arthritis specific autoantibodies, and the use thereof
    Patent number: 9249208
    Abstract: The invention relates to novel citrulline peptides derived from fibrin ? and ? chains which are recognizable by specific citrulline antiprotein autoantibodies (AAPC) of a rheumatoid arthritis (PR) and to the use thereof for detecting the presence of said specific PR AAPC in a biological sample.
    Type: Grant
    Filed: June 5, 2012
    Date of Patent: February 2, 2016
    Assignee: Biomerieux
    Inventors: Guy Serre, Mireille Sebbag
  • POLYPEPTIDE EXPRESSED IN THE STRATUM CORNEUM AND USE THEREOF
    Publication number: 20150299260
    Abstract: Polypeptides belonging to the family of late proteins of the cornified envelope (LCE), fragments of the polypeptide, isolated nucleotide sequences encoding the polypeptides, and cosmetic and/or pharmaceutical compositions containing such polypeptides are described. The polypeptides have cosmetic and/or therapeutic use to reinforce the barrier function of the epidermis, prevent and/or treat the signs of skin dryness and prevent and/or treat disorders of the barrier function or the weakening of the epidermis.
    Type: Application
    Filed: June 11, 2015
    Publication date: October 22, 2015
    Inventors: Nathalie JONCA, Eve TOULZA, Gaelle SAINTIGNY, Guy SERRE, Marina WEBER VIVAT
  • Polypeptide expressed in the stratum corneum and thereof
    Patent number: 9085635
    Abstract: A novel polypeptide isolated from the cornified envelope, similar polypeptides and fragments of the polypeptide, isolated nucleotide sequences encoding the polypeptides, as well as a cosmetic and/or pharmaceutical composition containing such polypeptides are described. The polypeptides have cosmetic and/or therapeutic use to reinforce the barrier function of the epidermis, prevent and/or treat the signs of skin dryness and prevent and/or treat disorders of the barrier function or the weakening of the epidermis.
    Type: Grant
    Filed: April 27, 2011
    Date of Patent: July 21, 2015
    Assignees: CHANEL PARFUMS BEAUTE, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE-CNRS, UNIVERSITE PAUL SABATIER TOULOUSE III
    Inventors: Nathalie Jonca, Eve Toulza, Gaelle Saintigny, Guy Serre, Marina Weber Vivat
  • PEPTIDYL ARGININE DEIMINASE 1 AND/OR 3 ACTIVATOR COMPOUNDS IN THE EPIDERMIS AND USES THEREOF
    Publication number: 20140030200
    Abstract: The present invention relates to the activation of peptidyl arginine deiminase (PADs) 1 and/or 3 in the epidermis by at least one active agent used alone or in combination, namely caffeine, acefylline and/or theobromine in a cosmetic and/or pharmaceutical composition. The present invention also relates to the use of the aforementioned active agents in cosmetics and/or therapeutics, alone or in combination, in order to improve the barrier functions of the epidermis, to prevent and/or treat symptoms related to dry skin or to improve and/or promote hydration of the keratinous layer. Finally, the invention relates to increasing the activity of PAD1 and/or PAD3 in the epidermis.
    Type: Application
    Filed: April 11, 2012
    Publication date: January 30, 2014
    Applicant: PIERRE FABRE DERMO-COSMETIQUE
    Inventors: Hélène Duplan, Sylvie Daunes-Marion, Stéphane Poigny, Marie-Claire Mechin, Guy Serre, Michel Simon
  • POLYPEPTIDE EXPRESSED IN THE STRATUM CORNEUM AND USE THEREOF
    Publication number: 20130053327
    Abstract: A novel polypeptide isolated from the cornified envelope, polypeptides similar to the latter or fragments of the polypeptide as well as a cosmetic and/or pharmaceutical composition containing same are described. The mainly cosmetic and/or therapeutic use of the polypeptide, or similar polypeptides or fragments of the amino acid sequence of the polypeptide, or an encoding nucleotide sequence for the polypeptide, to reinforce the barrier function of the epidermis and prevent and/or treat the signs of skin dryness or prevent and/or treat disorders of the barrier function or the fragilisation of the epidermis. Finally, the isolated encoding polynucleotide for the polypeptide are also disclosed.
    Type: Application
    Filed: April 27, 2011
    Publication date: February 28, 2013
    Applicants: CHANEL PARFUMS BEAUTE, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (C.N.R.S. ), UNIVERSITE PAUL SABATIER TOULOUSE III
    Inventors: Nathalie Jonca, Eve Toulza, Gaelle Saintigny, Guy Serre, Marina Weber Vivat
  • CITRULLINE PEPTIDES DERIVED FROM FIBRIN AND RECOGNIZED BY RHEUMATOID ARTHRITIS SPECIFIC AUTOANTIBODIES, AND THE USE THEREOF
    Publication number: 20130028922
    Abstract: The invention relates to novel citrulline peptides derived from fibrin ? and ? chains which are recognizable by specific citrulline antiprotein autoantibodies (AAPC) of a rheumatoid arthritis (PR) and to the use thereof for detecting the presence of said specific PR AAPC in a biological sample.
    Type: Application
    Filed: June 5, 2012
    Publication date: January 31, 2013
    Applicant: BIOMERIEUX
    Inventors: Guy Serre, Mireille Sebbag
  • Method for detecting rheumatoid arthritis-specific autoantibodies
    Patent number: 8241856
    Abstract: A method for detecting anti-filaggrin-autoantibodies specific to rheumatoid arthritis in a biological sample, by providing a filaggrin with no citrulline residues (FNC) having an arginine residue or a filaggrin peptide with no citrulline residues (PFNC) having an arginine residue. Also provided are a citrulline-containing filaggrin (FC) having the peptide sequence of the FNC where some arginine residues have been converted to citrulline residues or a citrulline-containing peptide (PFC) having the peptide sequence of the PFNC, where at least one arginine residue has been converted to a citrulline residue. The sample is contacted with the FNC or PFNC and the FC or PFC, and the resulting immune complexes are detected and quantified, with a value XNC and XC, respectively. Anti-filaggrin-autoantibodies specific to rheumatoid arthritis are determined to be present in the biological sample if the value of XC is greater than the value of XNC.
    Type: Grant
    Filed: June 13, 2002
    Date of Patent: August 14, 2012
    Assignee: Biomerieux
    Inventors: Brigitte Incaurgarat, Michel Jolivet, Odile Letourneur, Maria Léonor Nogueira, Mireille Sebbag, Guy Serre, Christian Vincent
  • Citrulline peptides derived from fibrin and recognized by rheumatoid arthritis specific autoantibodies, and the use thereof
    Patent number: 8207299
    Abstract: The invention relates to novel citrulline peptides derived from fibrin ? and ? chains which are recognizable by specific citrulline antiprotein autoantibodies (AAPC) of a rheumatoid arthritis (PR) and to the use thereof for detecting the presence of said specific PR AAPC in a biological sample.
    Type: Grant
    Filed: November 3, 2005
    Date of Patent: June 26, 2012
    Assignee: Biomerieux
    Inventors: Guy Serre, Mireille Sebbag
  • Peptides Modulating the Activity of Macrophages, Useable for the Treatment of Rheumatoid Arthritis
    Publication number: 20090298778
    Abstract: The invention relates to citrulline peptides with anti-inflammatory properties. The invention also relates to an in vitro model for activation of macrophages, induced by immune complexes between specified IgG of rheumatoid arthritis and their citrulline targets.
    Type: Application
    Filed: May 3, 2007
    Publication date: December 3, 2009
    Applicant: Universite Paul Sabatier
    Inventors: Cyril Clavel, Mireille Sebbag, Maria Leonor Nogueira, Guy Serre
  • CITRULLINE PEPTIDES DERIVED FROM FIBRIN AND RECOGNIZED BY RHEUMATOID ARTHRITIS SPECIFIC AUTOANTIBODIES, AND THE USE THEREOF
    Publication number: 20090028885
    Abstract: The invention relates to novel citrulline peptides derived from fibrin ? and ? chains which are recognisable by specific citrulline antiprotein autoantibodies (AAPC) of a rheumatoid arthritis (PR) and to the use thereof for detecting the presence of said specific PR AAPC in a biological sample.
    Type: Application
    Filed: November 3, 2005
    Publication date: January 29, 2009
    Inventors: Guy Serre, Mireille Sebbag
  • Fibrin citrulline derivatives and their use for diagnosing or treating rheumatoid arthritis
    Patent number: 7445903
    Abstract: The invention concerns citrulline polypeptide derived from fibrin useful for diagnosing or treating rheumatoid arthritis.
    Type: Grant
    Filed: January 26, 2006
    Date of Patent: November 4, 2008
    Assignee: Biomerieux SA
    Inventors: Guy Serre, Mireille Sebbag
  • Fibrin citrulline derivatives and their use for diagnosing or treating rheumatoid arthritis
    Publication number: 20070009507
    Abstract: The invention concerns citrulline polypeptide derived from fibrin useful for diagnosing or treating rheumatoid arthritis.
    Type: Application
    Filed: January 26, 2006
    Publication date: January 11, 2007
    Applicant: UNIVERSITE PAUL SABATIER-TOULOUSE III
    Inventors: Guy Serre, Mireille Sebbag