Abstract: The present invention relates to novel materials, particularly biomaterials, in form of a precipitate, comprising at least an anionic polymeric component which is as such soluble in water and an amphiphilic ammonium-type component, which precipitate is obtainable by a process including the following steps: 1. contacting the anionic polymeric component and an cyclodextrin component in an aqueous medium, and 2. adding to the mixture obtained in step 1 said amphiphilic ammonium-type component, wherein said components are present in amounts effective to form said precipitate, and preferably to corresponding precipitates additionally comprising said cyclodextrin component. Both types of precipitates may optionally comprise one or more further components. The precipitates are particularly useful as controlled-release depot formulations suitable for long-lasting delivery of said further components.

Abstract: The present invention relates in particular to a drug delivery system comprising a cyclofructan, a drug and a polymeric carrier.

Abstract: The invention provides a pharmaceutical package including a polypropylene bottle in which is disposed a solution containing a pharmaceutical product, where the solution does not fill the bottle completely and some air is disposed in the bottle, and where the package, after autoclaving at at least 121C and for at least 20 minutes, suffers no deformation, does not shrink, and does not explode, and where the package retains a sufficiently high squeezability to dispense the solution.

Abstract: Disclosed are ophthalmic compositions comprising ketotifen and pharmaceutically acceptable salts thereof, as well as methods for making such compositions.

Abstract: The present invention is related to an ophthalmic composition comprising ketotifen as a pharmaceutically active agent.

Abstract: The present invention is related to an ophthalmic composition comprising ketotifen as a pharmaceutically active agent.

Abstract: The present invention describes in particular a method for stabilizing a pharmaceutical composition by contacting said composition with a polymeric material comprising an antioxidant.

Abstract: The present invention is related to an ophthalmic composition comprising ketotifen as a pharmaceutically active agent.

Abstract: Disclosed are ophthalmic compositions comprising ketotifen and pharmaceutically acceptable salts thereof, as well as methods for making such compositions.

Abstract: The present invention describes an autoclavable ophthalmic composition comprising an ophthalmically effective drug. The invention further relates to a method for stabilizing an ophthalmic drug.

Abstract: The invention provides stabilized ophthalmic compositions and methods for stabilizing ophthalmic compositions.

Abstract: The invention provides stabilized ophthalmic compositions and methods for stabilizing ophthalmic compositions.

Abstract: A package for a pharmaceutical product, particularly a liquid ophthalmic composition, such as an ophthalmic solution, gel or ointment, for example a tube or a dropper bottle assembly used to dispense said product, wherein said package is made of a specific form of polypropylene and wherein said package shows after an autoclaving processing of at least 121° C. and for at least 20 minutes no deformation such as shrinkage or blowing-up and retains a sufficient high squeezability in order to dispense said product. Also claimed is a method for sterilizing a pharmaceutical package comprising the steps: placing closed package into an autoclaving chamber, adjusting the temperature and the pressure in said chamber as a function of time in accordance to the prerequisites of the material of said package, wherein a counter pressure is generated in said chamber and wherein this is regulated electronically via computer, and wherein said counter pressure avoids a deformation such as a blowing-up of said package.

Abstract: A method for preventing damage to mammalian eye tissues by UV-irradiation and ozone by applying to the eye a pharmaceutically effective amount of vitamin A and vitamin E.

Abstract: The present invention describes an ophthalmic composition comprising diclofenac potassium, the use of said composition as a medicament for treating inflammatory conditions of the eye, for treating glaucoma or for treating ear inflammatory and/or painful conditions (otitis); as well as the use of diclofenac potassium in the preparation of a pharmaceutical composition for treating any inflammatory condition of the eye, for treating glaucoma or for treating ear inflammatory and/or painful conditions (otitis).

Abstract: The present invention describes an ophthalmic composition diclofenac potassium, the use of said composition as a medicament for treating inflammatory conditions of the eye, for treating glaucoma or for treating ear inflammatory conditions and/or painful conditions (otitis)-l as well as the use of diclofenac potassium in the preparation of a pharmaceutical composition for the treatment of any inflammatory condition of the eye, for treating glaucoma or for treating ear inflammatory and/or painful conditions (otitis).