Patents by Inventor Gyula Beke

Gyula Beke has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Indole derivatives
    Patent number: 10329296
    Abstract: The present invention relates to compounds of the general form (I). The present invention relates to new substituted diazepino-indole derivatives of the general formula (I), and to pharmaceutically acceptable salts thereof, as well as to pharmaceutical compositions comprising such compounds, to new intermediate thereof, as well as to the use of such compounds in treatment or prevention of disorders associated with melanin-concentrating hormone receptor 1 activity.
    Type: Grant
    Filed: April 14, 2016
    Date of Patent: June 25, 2019
    Assignee: Richter Gedeon NYRT.
    Inventors: Gyula Beke, János Éles, András Boros, Sándor Farkas, György Miklós Keserü
  • INDOLE DERIVATIVES
    Publication number: 20180093989
    Abstract: The present invention relates to compounds of the general form (I). The present invention relates to new substituted diazepino-indole derivatives of the general formula (I), and to pharmaceutically acceptable salts thereof as well as to pharmaceutical compositions comprising such compounds, to new intermediate thereof as well as to the use of such compounds in treatment or prevention of disorders associated with melanin-concentrating hormone receptor 1 activity.
    Type: Application
    Filed: April 14, 2016
    Publication date: April 5, 2018
    Inventors: Gyula BEKE, János ÉLES, András BOROS, Sándor FARKAS, György Miklós KESERÜ
  • INDOLE DERIVATIVES
    Publication number: 20130217702
    Abstract: The present invention relates to the indole derivatives of formula (I), wherein R1-R6 and X are defined in the claims and optical antipodes or racemates and/or salts thereof which are selective antagonists of bradykinin B1 to process for producing these compounds, pharmacological compositions containing them and to their use in therapy or prevention of painful and inflammatory conditions.
    Type: Application
    Filed: November 4, 2011
    Publication date: August 22, 2013
    Inventors: Gyula Beke, Gyula Attila Bényei, István Borza, Éva Bozó, Sándor Farkas, Katalin Hornok, Andrea Papp, István Vágó, Mónika Vastag
  • Benzamide derivatives as bradykinin antagonists
    Patent number: 8481527
    Abstract: The present invention relates to new phenylsulfamoyl benzamide derivatives of formula (I) wherein R1-R5 and Z are as defined in the claims, and optical antipodes or racemates and/or salts and/or hydrates and/or solvates thereof, which are selective antagonists of bradykinin B1, to processes for producing these compounds, to pharmacological compositions containing them and to their use in therapy or prevention of painful and inflammatory conditions.
    Type: Grant
    Filed: October 27, 2007
    Date of Patent: July 9, 2013
    Assignee: Richter Gedeon Nyrt.
    Inventors: Istvan Vago, Gyula Beke, Eva Bozo, Sandor Farkas, Katalin Hornok, Gyorgy Keseru, Eva Schmidt, Eva Szentirmay, Monika Vastag
  • New Phenylsulfamoyl Benzamide Derivatives as Bradykinin Antagonists
    Publication number: 20130029991
    Abstract: The present invention relates to new sulfonamide derivatives of formula (I) wherein R1-R8 and Z are as defined in the claims, and optical antipodes or racemates and/or salts and/or hydrates and/or solvates thereof, which are selective antagonists of bradykinin B1, to processes for producing these same compounds, pharmacological compositions containing them and to their use in therapy or prevention of painful and inflammatory conditions.
    Type: Application
    Filed: August 1, 2012
    Publication date: January 31, 2013
    Inventors: Gyula Beke, Eva Bozo, Sandor Farkas, Katalin Hornok, Gyorgy Keseru, Eva Schmidt, Eva Szentirmay, Istvan Vago, Monika Vastag
  • New Phenylsulfamoyl Benzamide Derivatives as Bradykinin Antagonists
    Publication number: 20120295910
    Abstract: The present invention relates to new sulfonamide derivatives of formula (I), wherein R1-R8 and Z are as defined in the claims, and optical antipodes or racemates and/or salts and/or hydrates and/or solvates thereof, which are selective antagonists of bradykinin B1, to processes for producing these same compounds, pharmacological compositions containing them and to their use in therapy or prevention of painful and inflammatory conditions.
    Type: Application
    Filed: August 1, 2012
    Publication date: November 22, 2012
    Inventors: Gyula Beke, Eva Bozo, Sandor Farkas, Katalin Hornok, Gyorgy Keseru, Eva Schmidt, Eva Szentirmay, Istvan Vago, Monika Vastag
  • Phenanthridine derivatives as bradykinin antagonists
    Patent number: 8034827
    Abstract: The present invention relates to new phenanthridine derivatives of formula (I), wherein the variables are as defined in the specification, to processes for producing the same, to pharmacological compositions containing the same and to their use in therapy or prevention of painful and inflammatory processes.
    Type: Grant
    Filed: December 19, 2006
    Date of Patent: October 11, 2011
    Assignee: Richter Gegeon Nyrt.
    Inventors: Gyula Beke, Eva Bozo, Gabor Czira, Janos Eles, Sandor Farkas, Katalin Hornok, Eva Schmidt, Eva Szentirmay, Istvan Vago, Monika Vastag
  • NON-PEPTIDE DERIVATIVES AS BRADYKININ B1 ANTAGONISTS
    Publication number: 20100298299
    Abstract: The present invention relates to new non-peptide derivatives of formula (I), wherein R1-R5, Q and Z are as defined in the claims, and optical antipodes or racemates and/or salts and/or hydrates and/or solvates thereof, which are selective antagonists of bradykinin B1, to processes for producing these compounds, to pharmacological compositions containing them and to their use in therapy or prevention of painful and inflammatory conditions.
    Type: Application
    Filed: October 27, 2007
    Publication date: November 25, 2010
    Inventors: Istvan Vago, Sandor Farkas, Katalin Hornok, Gyula Beke, Eva Bozo, Monika Vastag, Eva Szentirmay, Gyorgy Keseru, Eva Schmidt
  • PHENYLSULFAMOYL BENZAMIDE DERIVATIVES AS BRADYKININ ANTAGONISTS
    Publication number: 20100105686
    Abstract: The present invention relates to new sulfonamide derivatives of formula (I) wherein R1-R8 and Z are as defined in the claims, and optical antipodes or racemates and/or salts and/or hydrates and/or solvates thereof, which are selective antagonists of bradykinin B1, to processes for producing these same compounds, pharmacological compositions containing them and to their use in therapy or prevention of painful and inflammatory conditions.
    Type: Application
    Filed: October 27, 2007
    Publication date: April 29, 2010
    Inventors: Gyula Beke, Eva Bozo, Sandor Farkas, Katalin Hornok, Gyorgy Keseru, Eva Schmidt, Eva Szentirmay, Istvan Vago, Monika Vastag
  • NEW BENZAMIDE DERIVATIVES AS BRADYKININ ANTAGONISTS
    Publication number: 20100087423
    Abstract: The present invention relates to new phenylsulfamoyl benzamide derivatives of formula (I) wherein R1-R5 and Z are as defined in the claims, and optical antipodes or racemates and/or salts and/or hydrates and/or solvates thereof, which are selective antagonists of bradykinin B1, to processes for producing these compounds, to pharmacological compositions containing them and to their use in therapy or prevention of painful and inflammatory conditions.
    Type: Application
    Filed: October 27, 2007
    Publication date: April 8, 2010
    Inventors: Istvan Vago, Gyula Beke, Eva Bozo, Sandor Farkas, Katalin Hornok, Gyorgy Keseru, Eva Schmidt, Eva Szentirmay, Monika Vastag
  • SULFONAMIDE DERIVATIVES AS BRADYKININ ANTAGONISTS
    Publication number: 20100075978
    Abstract: The present invention relates to new sulfonamide derivatives of formula (I) wherein R1-R5 and Z are as defined in the claims, and optical antipodes or racemates and/or salts and/or hydrates and/or solvates thereof, which are selective antagonists of bradykinin B1, to processes for producing these compounds, pharmacological compositions containing them and to their use in therapy or prevention of painful and inflammatory conditions.
    Type: Application
    Filed: October 27, 2007
    Publication date: March 25, 2010
    Inventors: Eva Bozo, Gyula Beke, Janos Eles, Sandor Farkas, Katalin Hornok, Gyorgy Keseru, Eva Schmidt, Eva Szentirmay, Istvan Vago, Monika Vastag
  • PHENANTHRIDINE DERIVATIVES AS BRADYKININ ANTAGONISTS
    Publication number: 20090270411
    Abstract: The present invention relates to new phenanthridine derivatives of formula (I), wherein the variables are as defined in the specification, to processes for producing the same, to pharmacological compositions containing the same and to their use in therapy or prevention of painful and inflammatory processes.
    Type: Application
    Filed: December 19, 2006
    Publication date: October 29, 2009
    Inventors: Gyula Beke, Eva Bozo, Gabor Czira, Janos Eles, Sandor Farkas, Katalin Hornok, Eva Schmidt, Eva Szentirmay, Istvan Vago, Monika Vastag