Patents by Inventor H. Glenn Corkins

H. Glenn Corkins has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Process for the production of thyroglobulin
    Patent number: 5099001
    Abstract: The invention relates to a process for the production of thyroglobulin, which is used in the treatment of hypothyroidism, from hog thyroid glands. Ground hog thyroid glands are subjected to saline digestion to produce a thyroglobulin extract. The extract is precipitated by pH adjustment and then heated to a denaturing temperature. The denatured precipitated thyroglobulin solution is subjected to a separation step to produce crude wet thyroglobulin solids. The crude thyroglobulin solids are defatted and dewatered by solvent extraction. The resultant defatted thyroglobulin product can then be further worked up, for example, by drying, milling, and screening, to produce a powdered product. In order to achieve a final product having a T.sub.4 /T.sub.3 ratio of 2.6-3.4 and upon proteolysis a minimum of 0.7 .mu.g/mg of levothyronine and 2.1 .mu.g/mg of liothyronine, the time periods for the precipitating, denaturing, and/or defatting steps are carefully controlled so that the T.sub.4 /T.sub.
    Type: Grant
    Filed: December 28, 1989
    Date of Patent: March 24, 1992
    Assignee: Nepera, Inc.
    Inventors: Louis Scarano, H. Glenn Corkins
  • Insecticidal and nematocidal heterobicyclic hydroximinates, thiohydroximidates, and carbamate esters, composition, and method of use thereof
    Patent number: 4548929
    Abstract: Novel heterobicyclic compounds of Formula I, processes for preparing same and pesticidal compositions and methods are described.
    Type: Grant
    Filed: April 18, 1983
    Date of Patent: October 22, 1985
    Assignee: SDS Biotech Corporation
    Inventors: Thomas A. Magee, Robert D. Battershell, Lawrence E. Limpel, Andrew W. Ho, Arthur W. Friedman, H. Glenn Corkins, William W. Brand, Russell Buchman, Louis Storace, Edmond R. Osgood
  • Biologically active heterobicyclic hydroximidates and thiolhydroximidates and carbamate ester derivatives thereof
    Patent number: 4424213
    Abstract: Novel heterobicyclic compounds of Formula I, processes for preparing same and pesticidal compositions and methods are described.
    Type: Grant
    Filed: November 2, 1981
    Date of Patent: January 3, 1984
    Assignee: SDS Biotech Corporation
    Inventors: Thomas A. Magee, Robert D. Battershell, Lawrence E. Limpel, Andrew W. Ho, Arthur W. Friedman, H. Glenn Corkins, William W. Brand, Russell Buchman, Louis Storace, Edmond R. Osgood
  • Preparation of S-chloromethylated O-alkyl substituted phosphodithioic acids
    Patent number: 4264533
    Abstract: A novel and efficient method for preparing S-chloromethyl derivatives of O-alkylphosphorodithioic acids involves reacting the S-hydroxymethyl derivative of such an acid under substantially anhydrous conditions with a suitable acid chloride in a chemically unreactive organic liquid which is a solvent for both said S-hydroxymethyl derivative and said acid chloride. Suitable acid chlorides are PCl.sub.5, PCl.sub.3, acetyl chloride, chlorinated derivatives of acetyl chloride, oxyalyl chloride, phosgene, thionyl chloride, sulfuryl chloride, aryl sulfonyl chlorides and chloro- or nitro-substituted aryl sulfonyl chlorides.
    Type: Grant
    Filed: December 4, 1979
    Date of Patent: April 28, 1981
    Assignee: Diamond Shamrock Corporation
    Inventors: H. Glenn Corkins, Louis Storace, William W. Brand
  • Method of preparing ketoxime carbamates
    Patent number: 4264528
    Abstract: A novel process of preparing ketoxime carbamate by forming a halogenated intermediate which is reacted with an alkali metal compound and an isocyanate.
    Type: Grant
    Filed: June 18, 1980
    Date of Patent: April 28, 1981
    Assignee: Diamond Shamrock Corporation
    Inventor: H. Glenn Corkins