Patents by Inventor Hadar Hana Feinberg

Hadar Hana Feinberg has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Hybrid amyloid-beta antibodies
    Patent number: 9067981
    Abstract: The present invention provides crystals including amino acids 1-7 of SEQ ID NO:1 and a Fab fragment of 12A11, 12B4, 10D5 or 3D6, as well as of amino acids 1-40 of SEQ ID NO:1 and a Fab fragment of 12A11 or 3D6, as well as methods for preparing the crystals. The present invention also provides a computer implemented method for analyzing binding of a candidate antibody fragment to a peptide including an epitope of amino acids 1-7 of SEQ ID NO:1, a method for identifying an antibody fragment that can mimic the Fab fragment of 12A11, a method for identifying an antibody fragment that can mimic the Fab fragment of 3D6, a method for identifying a candidate antibody fragment that binds to a peptide including an epitope of amino acids 1-7 of SEQ ID NO:1, and a method for designing a humanized antibody that binds to a peptide comprising an epitope of amino acids 1-7 of SEQ ID NO:1.
    Type: Grant
    Filed: October 29, 2009
    Date of Patent: June 30, 2015
    Assignees: JANSSEN SCIENCES IRELAND UC, WYETH LLC, THE BOARD OF TRUSTEES OF LELAND STANFORD JR. UNIVERSITY
    Inventors: Guriqbal Basi, Dale B. Schenk, Hadar Hana Feinberg, William I. Weis