Abstract: A method of detecting and classifying facial muscle movements, comprising the steps of: receiving bio-signals from at least one bio-signal detector; and applying at least one facial muscle movement-detection algorithm to a portion of the bio-signals affected by a predefined type of facial muscle movement in order to detect facial muscle movements of that predefined type.

Abstract: The present invention relates to compositions comprising and methods for producing adenovirus compositions wherein host cells are grown in a bioreactor and purified by size partitioning purification to provide purified adenovirus compositions.

Abstract: A method of detecting a mental state includes receiving, in a processor, bio-signals of a subject from one or more bio-signal detectors, and determining in the processor whether the bio-signals represent the presence of a particular mental state in the subject. A method of using the detected mental state includes receiving, in a processor, a signal representing whether a mental state is present in the subject. The mental state can be a non-deliberative mental state, such as an emotion, preference or sensation. A processor can configured perform the methods, and a computer program product, tangibly stored on machine readable medium can have instructions operable to cause a processor to perform the methods.

Abstract: A method and apparatus are provided for reducing leakage current in a read only memory device. Leakage current is reduced by reducing the duration of the precharge cycle during each read cycle so that the associated leakage current will flow for a shorter time period during each cycle. The precharge phase is positioned at the beginning of each read cycle, prior to the evaluation phase.

Abstract: A method of detecting and classifying mental states, comprising the steps of receiving bio-signals from one or more bio-signal detectors; generating multiple different representations of each bio-signal; determining the value of one or more features of the each bio-signal representation; and comparing the feature values to one or more than one mental state signature, each mental state signature defining reference feature values indicative of a predetermined mental state.

Abstract: A method of detecting and classifying mental states, comprising the steps of: detecting bio-signals from one or more than one bio-signal detector; transforming the bio-signals into one or more than one different representations; detecting values of one or more than one property of the transformed bio-signal representations; and applying one or more than one mental state detection algorithm to the detected properties in order to classify whether the bio-signals indicate the presence of a predetermined response by a subject.

Abstract: A method of detecting and classifying facial muscle movements, comprising the steps of: detecting bio-signals from a plurality of scalp electrodes; and applying one or more than one facial muscle movement-detection algorithm to a portion of the bio-signals affected by a predefined type of facial muscle movement in order to detect facial muscle movements of that predefined type.

Abstract: The present invention relates to improved methods for producing adenovirus compositions wherein host cells are grown in a bioreactor and purified by size partitioning purification to provide purified adenovirus compositions.

Abstract: A method and apparatus are provided for reducing leakage current in a read only memory device. Leakage current is reduced by applying a biased gate voltage (relative to a source voltage) to the gate of at least one of transistor in the array. The biased gate voltage is applied at least during a precharge phase of a read cycle. When the array transistors are n-channel transistors, the biased voltage is a negative bias voltage (relative to the source voltage). When the array transistors are p-channel transistors, the biased voltage is a positive bias voltage (relative to the source voltage). Applying a negative backgate bias to the transistor's p-well contact can also reduce n-channel transistor subthreshold leakage current. Thus, for an n-channel array, a negative gate voltage and backgate bias (optional) are applied to cell transistors in the off state.

Abstract: A method and apparatus are provided for reducing leakage current in a read only memory device. Leakage current is reduced by reducing the duration of the precharge cycle during each read cycle so that the associated leakage current will flow for a shorter time period during each cycle. The precharge phase is positioned at the beginning of each read cycle, prior to the evaluation phase. The precharge phase is terminated by a subsequent clock edge or by an internal time out prior to a subsequent clock edge. The time interval between when the columns reach their precharge voltage and the evaluation phase begins is reduced.

Abstract: The present invention addresses the need to improve the yield of adenovirus when grown in cell culture systems. In particular, it has been demonstrated that for adenovirus, the use of infection temperatures lower than 37° C. in a cell culture system results in improved yields of adenovirus. In addition, it has been demonstrated that when host cells are grow in a bioreactor, initiating adenovirus infection by diluting the host cells with fresh media and adenovirus results in improved yield of adenovirus. Methods of adenoviral production and purification using infection temperatures less than 37° C. are disclosed. Methods of adenoviral production and purification wherein the host cells are grown in a bioreactor and adenovirus infection is initiated by diluting the host cells with fresh media and adenovirus are also disclosed.

Abstract: The present invention addresses the need to improve the yield of adenovirus when grown in cell culture systems. In particular, it has been demonstrated that for adenovirus, the use of infection temperatures lower than 37° C. in a cell culture system results in improved yields of adenovirus. In addition, it has been demonstrated that when host cells are grow in a bioreactor, initiating adenovirus infection by diluting the host cells with fresh media and adenovirus results in improved yield of adenovirus. Methods of adenoviral production and purification using infection temperatures less than 37° C. are disclosed. Methods of adenoviral production and purification wherein the host cells are grown in a bioreactor and adenovirus infection is initiated by diluting the host cells with fresh media and adenovirus are also disclosed.