Abstract: A digital receiver is configured to process a polarization multiplexed carrier from a communication network. The polarization multiplexed carrier includes a first polarization and a second polarization. The receiver includes a first lane for transporting a first input signal of the first polarization, a second lane for transporting a second input signal of the second polarization, a dynamic phase noise estimation unit disposed within the first lane and configured to determine a phase noise estimate of the first input signal, a first carrier phase recovery portion configured to remove carrier phase noise from the first polarization based on a combination of the first input signal and a function of the determined phase noise estimate, and a second carrier phase recovery portion configured to remove carrier phase noise from the second polarization based on a combination of the second input signal and the function of the determined phase noise estimate.

Abstract: An edge wavelength-switching system includes an optical switch and a wavelength selective switch. The optical switch includes a west hub-side port, an east hub-side port, a west local-side port, and an east local-side port. The wavelength selective switch includes (i) a multiplexed port optically coupled to the west local-side port and (ii) a bypass port optically coupled to the east local-side port, and (iii) a plurality of demultiplexed ports. An optical network includes a network hub including an M-by-N1 wavelength-selective switch, N1>M?1, a first network node, and a second network node. Each of the first and second network nodes includes a respective edge wavelength-switching system. The network hub, the first network node, and the second network node are optically coupled.

Abstract: An injection locked transmitter for an optical communication network includes a master seed laser source input substantially confined to a single longitudinal mode, an input data stream, and a laser injected modulator including at least one slave laser having a resonator frequency that is injection locked to a frequency of the single longitudinal mode of the master seed laser source. The laser injected modulator is configured to receive the master seed laser source input and the input data stream, and output a laser modulated data stream.

Abstract: Disclosed is use of alphavirus in preparation of antitumor drugs. The alphavirus is M1 virus or Getah virus. In addition, the specific tumor types sensitive to abovementioned alphavirus treatment are further determined, so as to provide a safe and effective solution for antitumor drug administering schemes.

Abstract: A skew compensation system for a coherent optical communication network includes a transmitter modulator having a first driver input for receiving a first signal from a first channel, a second driver input for receiving a second signal from a second channel, a source input for receiving a continuous wave source signal, and a modulation output in communication with an optical transport medium of the network. The system further includes a tunable delay line disposed between the second channel and the second driver input for inserting a pre-determined training sequence onto the second signal prior to the second driver input, and a processor for determining a skew amount between the second signal at the second driver input and the first signal at the first driver input, calculating a pre-compensation value corresponding to the skew amount, and reducing the skew amount at the modulation output according to the pre-compensation value.

Abstract: A full duplex communication network includes an optical transmitter end having a first coherent optics transceiver, an optical receiver end having a second coherent optics transceiver, and an optical transport medium operably coupling the first coherent optics transceiver to the second coherent optics transceiver. The first coherent optics transceiver is configured to simultaneously transmit a downstream optical signal and receive an upstream optical signal. The second coherent optics transceiver is configured to simultaneously receive the downstream optical signal from the first coherent optics transceiver and transmit the upstream optical signal first coherent optics transceiver. At least one of the downstream optical signal and the upstream optical signal includes at least one coherent optical carrier and at least one non-coherent optical carrier.

Abstract: A full duplex communication network includes an optical transmitter end having a first coherent optics transceiver, an optical receiver end having a second coherent optics transceiver, and an optical transport medium operably coupling the first coherent optics transceiver to the second coherent optics transceiver. The first coherent optics transceiver is configured to simultaneously transmit a downstream optical signal and receive an upstream optical signal. The second coherent optics transceiver is configured to simultaneously receive the downstream optical signal from the first coherent optics transceiver and transmit the upstream optical signal first coherent optics transceiver. At least one of the downstream optical signal and the upstream optical signal includes at least one coherent optical carrier and at least one non-coherent optical carrier.

Abstract: Disclosed is use of alphavirus in preparation of antitumor drugs. The alphavirus is M1 virus or Getah virus. In addition, the specific tumor types sensitive to abovementioned alphavirus treatment are further determined, so as to provide a safe and effective solution for antitumor drug administering schemes.

Abstract: An optical communication network includes a downstream optical transceiver. The downstream optical transceiver includes at least one coherent optical transmitter configured to transmit a downstream coherent dual-band optical signal having a left-side band portion, a right-side band portion, and a central optical carrier disposed within a guard band between the left-side band portion and the right-side band portion. The network further includes an optical transport medium configured to carry the downstream coherent dual-band optical signal from the downstream optical transceiver. The network further includes at least one modem device operably coupled to the optical transport medium and configured to receive the downstream coherent dual-band optical signal from the optical transport medium. The at least one modem device includes a downstream coherent optical receiver, and a first slave laser injection locked to a frequency of the central optical carrier.

Abstract: An optical line terminal includes an optical comb generator, N downlink channels Dk, and N uplink-photodetectors PDk. The optical comb generator is configured to generate a carrier signal having an optical-frequency-comb spectrum and including N optical tones Tk and N optical tones Rk, k={1, 2, . . . , N}. Each of the N downlink channels Dk is optically coupled to the optical comb generator and is configured to generate a respective downlink signal DSk that includes optical tone Tk modulated by downlink data. Each of the N uplink-photodetectors PDk is configured to receive a respective one of a plurality of modulated uplink signals USk, having optical tone Rk as a carrier signal.

Abstract: Methods, systems, and computer readable media for social grouping are provided to perform social grouping of a user's contacts based on the user's interactions with the contacts. A set of attributes associated with interactions between a user and a set of contacts may be determined by a first device. The set of attributes associated with the interactions may be related to the first device. The set of contacts may be organized into a set of groups based on the set of attributes.

Abstract: Methods, systems, and apparatus, including computer programs encoded on computer storage media, for writing data in one or more storage units. One of the methods includes obtaining an erasing count for each of multiple storage units, wherein the erasing count equals a total count of erasing operations that have been performed on all blocks of the storage unit. The method further includes identifying one or more of the storage units that satisfy one or more conditions associated with writing data, determining a storage unit that has the smallest erasing count among the identified storage units, and writing the data in the determined storage unit.

Abstract: This invention belongs to the field of biomedicine and relates to use of Bcl-xL inhibitor and oncolytic virus in the preparation of an anti-tumor drug. The present invention firstly discovers that the Bcl-xL inhibitor can be used as an anti-tumor synergist for oncolytic virus. The present invention also relates to a pharmaceutical composition comprising Bcl-xL inhibitor and oncolytic virus, a pharmaceutical kit comprising Bcl-xL inhibitor and oncolytic virus, and use of Bcl-xL inhibitor and oncolytic virus for treating tumors, especially, tumors that are not sensitive to the oncolytic virus.

Abstract: A full duplex communication network includes an optical transmitter end having a first coherent optics transceiver, an optical receiver end having a second coherent optics transceiver, and an optical transport medium operably coupling the first coherent optics transceiver to the second coherent optics transceiver. The first coherent optics transceiver is configured to (i) transmit a downstream optical signal at a first wavelength, and (ii) simultaneously receive an upstream optical signal at a second wavelength. The second coherent optics transceiver is configured to (i) receive the downstream optical signal, and (ii) simultaneously transmit the upstream optical signal. The first wavelength has a first center frequency separated from a second center frequency of the second wavelength.

Abstract: The present invention belongs to the field of biomedicine and relates to use of VCP (valosin-containing protein, VCP) inhibitor and oncolytic virus in the preparation of an anti-tumor drug. The present invention firstly discovers that VCP inhibitor can be used in the preparation of an anti-tumor synergist for oncolytic virus. Meanwhile, the present invention relates to a pharmaceutical composition comprising VCP inhibitor and oncolytic virus, a pharmaceutical kit comprising VCP inhibitor and oncolytic virus, and use of VCP inhibitor and oncolytic virus for treating tumor, especially a tumor that is not sensitive to oncolytic virus. The present invention also relates to an anti-tumor administration system, characterized in that, comprising oncolytic virus and a reagent for detecting the expression level of VCP.

Abstract: Described herein is use of a Caspase activator and an oncolytic virus in the preparation of an anti-tumor drug. As described, Caspase activator can enhance the anti-tumor effect of oncolytic virus, and the combination of Caspase activator and oncolytic virus produces a significant synergistic anti-tumor effect, and demonstrates an effective therapy for the treatment of tumors that are less sensitive to other pharmaceutical treatments.

Abstract: Disclosed is use of alphavirus in preparation of antitumor drugs. The alphavirus is M1 virus or Getah virus. In addition, the specific tumor types sensitive to abovementioned alphavirus treatment are further determined, so as to provide a safe and effective solution for antitumor drug administering schemes.

Abstract: The disclosure provides a method and device for switching an operating mode of a remote controller so as to address the problem in the prior art of inconvenient operations of switching the mode of the remote controller to thereby improve the experience of a user. The method for switching an operating mode of a remote controller includes: receiving a first pairing instruction transmitted by a first remote controller in an infrared mode, wherein the first pairing instruction carries the first device identifier of the first remote controller; searching a list of stored device identifiers to determine whether the first device identifier is present in the list; if so, then performing a pairing flow, and the remote controller is switched to the radio mode after a successful paring; otherwise, rejecting the first pairing instruction.

Abstract: Expanded beam (EB) connector includes a fiber holder having an alignment channel that is configured to receive an optical fiber. The alignment channel has a channel opening and extends from the channel opening to a channel end face. The EB connector also includes an optical substrate having a three-dimensional (3D) waveguide that includes a waveguide core and a cladding. The optical substrate includes the channel end face. The waveguide core extends lengthwise between first and second coupling faces of the waveguide core. The first coupling face is at least a portion of the channel end face. The first coupling face is configured to optically couple to the optical fiber disposed within the alignment channel. The second coupling face defines an exterior of the optical substrate. The waveguide core is shaped to change a mode field diameter and a numerical aperture of light propagating between the first and second coupling faces.

Abstract: An electrochromic test port provides an actively tunable system for building an optical test port for an optical waveguide with enhanced SNR properties over conventional approaches.