Abstract: Systems and methods described herein can involve training a functional encoder involving a plurality of layers of continuous neurons from input time series data to learn a dimension reduced form of the input time series data, the dimension reduced form of the input time series data being at least one of a feature reduced or time point reduced form of the input time series data; and training a functional decoder comprising another plurality of layers of continuous neurons to learn the input time series data from the dimension reduced form of the input time series data.

Abstract: The present invention provides a slushy cup capable of realizing quick heat exchange. The slushy cup capable of realizing quick heat exchange includes an inner core, an outer cup body, and a sealing connection sleeve sleeving the outer cup body, wherein the sealing connection sleeve stores a refrigerant in an interlayer in a sealing manner through multi-layer sealing, and convex ribs are distributed on an outer circumferential side wall of a main body portion of the inner core, thereby increasing a contact area of heat exchange and enhancing the strength of an outer wall of the inner core. Through full contact between the convex ribs on an outer surface of the inner core and the refrigerant, cold energy of the refrigerant in the interlayer is quickly conducted to a drink in the inner core to quickly cool the drink into a slushy drink.

Abstract: An optical lens, an optical module, and an electronic device are provided. The optical lens includes: a first lens (1), a reflector (2), a diaphragm (3), a second lens (4), a third lens (5), a fourth lens (6), and a fifth lens (7) in sequence from an object side to an image side.

Abstract: A knowledge graph embedding-based approach to content labeling is used for targeted content delivery in a web platform, such as a job website. Job posting data of the web platform is normalized and used to train a knowledge graph embedding. Labels are determined for job posting data of the web platform using the trained knowledge graph embedding, and mappings are determined between the labels and segments of users of the web platform. Current user data is obtained for a user of the web platform. A current segment to which the user corresponds is determined based on the current user data, a current mapping to which the current segment corresponds is determined based on the current segment, and targeted content to deliver to a device of the user is determined according to the current mapping. The targeted content may then be delivered to the user device.

Abstract: A visual loop-mediated isothermal amplification (LAMP) method for a rapid test of tobacco includes: extracting a genomic DNA of the tobacco, designing primers, establishing a LAMP reaction system, and optimizing the LAMP reaction system. The present disclosure designs the LAMP primers according to a conserved region of a screened tobacco-specific Ntsp151 genomic sequence, and establishes the LAMP method based on color determination. The present disclosure can rapidly identify flue-cured tobacco leaves, finished cigarettes, and tea cigarettes, and achieves a detection limit of 200 copies per reaction. The test results of the LAMP method for non-tobacco samples are negative, indicating that the LAMP method has high specificity. Compared with the quantitative polymerase chain reaction (qPCR) method, the LAMP method has a coincidence rate of 96.7%, but the LAMP method only needs about 1 h to obtain the results.

Abstract: A cartilage extract with the effect of improving immune response, a preparation method therefor, and a use thereof. The cartilage extract uses animal cartilage as a raw material, and a cartilage extract containing an effective amount of undenatured type II collagen for improving immune response is obtained by adding sodium hyaluronate and lentinan at a mass ratio of 4:1 to 1:1, being capable of simultaneously preventing microbial spoilage of the cartilage extract and denaturation of the type II collagen during the storage period, and thereby improving the safety and storability of the product. The obtained cartilage extract has the advantages of high safety and effectiveness and has the effects of improving immune response, increasing the content of serum anti-inflammatory factors such as TGF-?, and reducing the content of inflammatory factors such as TNF-?, and can therefore be added to health food or functional food as a food raw material.

Abstract: The use of a genetic method to down-regulate RBO/EFR3/EFR3A/EFR3B proteins, TTC7 protein or PI4KIII? enzyme protein which interacts with RBO/EFR3/EFR3A/EFR3B proteins and TTC7 protein, or the use of a drug to inhibit PI4KIII? protein kinase activity reduces the accumulation of A?42 within neurons and age-dependent synaptic transmission failure and other obstacles in a fruit fly AD model, and obtains an effect of improving the learning and memory abilities of AD model mice. Provided is a method for using an RBO/EFR3/EFR3A/EFR3B inhibitor, a TTC7 inhibitor and a PI4KIII? inhibitor to treat Alzheimer's disease. Also provided is a method for screening a drug treating Alzheimer's disease by whether A? secretion by nerve cells is promoted or not.

Abstract: The present disclosure provides an organic light-emitting diode display panel, a method for preparing the same, and a display device. The organic light-emitting diode display panel includes a substrate, a light-emitting structure layer arranged on the substrate, and a light modulation layer arranged on a light exiting path of the light-emitting structure layer and configured to adjust a direction of an emergent light beam.

Abstract: A new trans-impedance amplifier (TIA) with low noise is provided. The TIA may include an input stage and an output driving stage. The input stage may include a pair of input PMOS transistors, a pair of input NMOS transistors, and a pair of differential voltage input nodes. The output driving stage may include a pair of output circuits, each may include a first pair of PMOS and NMOS transistors electrically connected in parallel, a second pair of PMOS and NMOS transistors electrically connected in series, and a pair of capacitors electrically connected in series, which are electrically connected in parallel. The structure can lead to a reduced noise level of the TIA.

Abstract: A refrigerator includes a refrigerator body and a door body. In a case where the door body is opened from a closed state to a first state, a first hinge shaft moves from a first positioning position to a second positioning position along a first positioning trajectory line with respect to a first trajectory slot, and a second hinge shaft moves from a first guiding position to a second guiding position along a first guiding trajectory line with respect to a second trajectory slot. In a case where the door body continues to be opened from the first state to a second state, the first hinge shaft moves from the second positioning position to a third positioning position along a second positioning trajectory line, the second hinge shaft moves from the second guiding position to a third guiding position along a second guiding trajectory line.

Abstract: The present disclosure relates to methods of treating a patient with a cancer by administering to the patient a composition comprising CAR T cells and a small molecule linked to a targeting moiety by a linker. The disclosure also relates to compositions for use in such methods.

Abstract: Provided herein is an electro-optic display having a layer of electrophoretic material, a first conductive layer, and a piezoelectric material positioned between the layer of electrophoretic material and the first conductive layer, the piezoelectric material overlaps with a portion of the layer of electrophoretic material, and a portion of the first conductive layer overlaps with the rest of the electrophoretic material.

Abstract: A product dispenser with a reservoir for a product and a cap. The cap has a first assembly and a second assembly. The first assembly can include a button configured to dispense the product through a lower end orifice of the pipette, when the button is actuated. The second assembly can include a pipette rigidly connected and in fluidic communication with a chamber configured to change its volume depending on the movement of the first assembly relative to the second assembly and the movement of the button.

Abstract: Novel quinazolinones useful as inhibitors of tau oligomer formation, useful for the treatment of neurodegenerative diseases and related conditions are disclosed. The invention also relates to the pharmaceutically acceptable salts of said compounds, processes for the preparation of said compounds, intermediates used in the preparation of said compounds, and pharmaceutical compositions containing said compounds. The invention further relates to methods of use of said compounds, salts of said compounds, and said compositions in treating neurodegenerative diseases and related conditions.

Abstract: Methods and compositions for treating a siliceous geologic formation are described herein. An aqueous treatment composition for treating such formations includes an acid having molecular weight less than about 200, or an ammonium or sodium salt thereof, an HF source, and from about 0.1 wt % to about 2.0 wt % of a fluoride scale inhibitor, the aqueous treatment composition having a pH from about 1.0 to about 3.0.

Abstract: A method produces tantalum powder. The method includes: (1) uniformly mixing a tantalum powder raw material, metal magnesium and at least one alkali metal and/or alkaline earth metal halide, loading the mixture into a container, and putting the container in a furnace; (2) raising the temperature of the furnace to 600-1200° C. in the presence of inert gas, and soaking; (3) at the end of soaking, lowering the temperature of the furnace to 600-800° C., vacuumizing the interior of the furnace to 10 Pa or less, soaking under the negative pressure so that the excessive metal is separated; (4) thereafter, raising the temperature of the furnace to 750-1200° C. in the presence of inert gas, and soaking so that the tantalum powder is sintered in the molten salt after oxygen reduction; (5) then cooling to room temperature and passivating to obtain a mixed material containing halide and tantalum powder; and (6) separating the tantalum powder from the resulting mixture.

Abstract: A gummy composition including a set emulsification of an oil phase and a water phase, and a water-soluble active ingredient. A method including administering a gummy composition including a set emulsification of an oil phase and a water phase, and a water-soluble active ingredient.

Abstract: Novel benzofurans, benzothiophenes and indoles useful as inhibitors of tau oligomer formation, useful for the treatment of neurodegenerative diseases and related conditions are disclosed. The invention also relates to the pharmaceutically acceptable salts of said compounds, processes for the preparation of said compounds, intermediates used in the preparation of said compounds, and pharmaceutical compositions containing said compounds. The invention further relates to methods of use of said compounds, salts of said compounds, and said compositions in treating neurodegenerative diseases and related conditions.