Patents by Inventor Haiyan Jiang

Haiyan Jiang has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • TARGETED COAGULATION FACTORS AND METHOD OF USING THE SAME
    Publication number: 20140221618
    Abstract: Targeted coagulation factors comprising a coagulation factor linked with at least one domain that specifically binds to a membrane protein on a blood cell is provided. The disclosed targeted coagulation factors increase the efficiency of coagulation factors and prolong their duration of action and thus, are an improvement for the treatment of hematological diseases such as hemophilia A.
    Type: Application
    Filed: April 15, 2014
    Publication date: August 7, 2014
    Inventors: Richard Feldman, Ji-Yun Kim, Haiyan Jiang, Kirk Mclean, Junliang Pan, Glenn Pierce, James Wu, Xiao-Yan Zhao
  • Factor VIII-Fc Chimeric and Hybrid Polypeptides, and Methods of Use Thereof
    Publication number: 20130274194
    Abstract: The present invention provides methods of administering Factor VIII; methods of administering chimeric and hybrid polypeptides comprising Factor VIII; chimeric and hybrid polypeptides comprising Factor VIII; polynucleotides encoding such chimeric and hybrid polypeptides; cells comprising such polynucleotides; and methods of producing such chimeric and hybrid polypeptides using such cells.
    Type: Application
    Filed: March 11, 2013
    Publication date: October 17, 2013
    Inventors: Jennifer A. Dumont, Susan Low, Alan J. Bitonti, Glenn Pierce, Alvin Luk, Haiyan Jiang, Byron McKinney, Matt Ottmer, Jurg Sommer, Karen Nugent, Lian Li, Robert Peters
  • Factor IX Polypeptides and Methods of Use Thereof
    Publication number: 20130202595
    Abstract: The present invention provides methods of administering Factor IX; methods of administering chimeric and hybrid polypeptides comprising Factor IX; chimeric and hybrid polypeptides comprising Factor IX; polynucleotides encoding such chimeric and hybrid polypeptides; cells comprising such polynucleotides; and methods of producing such chimeric and hybrid polypeptides using such cells.
    Type: Application
    Filed: July 11, 2011
    Publication date: August 8, 2013
    Applicant: Biogen Idec Hemophilia Inc.
    Inventors: Glenn Pierce, Samantha Truex, Robert T. Peters, Haiyan Jiang
  • Factor VIII-Fc Chimeric and Hybrid Polypeptides, and Methods of Use Thereof
    Publication number: 20130108629
    Abstract: The present invention provides methods of administering Factor VIII; methods of administering chimeric and hybrid polypeptides comprising Factor VIII; chimeric and hybrid polypeptides comprising Factor VIII; polynucleotides encoding such chimeric and hybrid polypeptides; cells comprising such polynucleotides; and methods of producing such chimeric and hybrid polypeptides using such cells.
    Type: Application
    Filed: December 6, 2010
    Publication date: May 2, 2013
    Applicant: BIOGEN IDEC HEMOPHILIA INC.
    Inventors: Jennifer A. Dumont, Susan Low, Alan J. Bitonti, Glenn Pierce, Alvin Luk, Haiyan Jiang, Byron McKinney, Matt Ottmer, Jurg Sommer, Karen Nugent, Lian Li, Robert Peters
  • Factor VIII Compositions and Methods of Making and Using Same
    Publication number: 20130017997
    Abstract: The present invention relates to compositions comprising factor VIII coagulation factors linked to extended recombinant polypeptide (XTEN), isolated nucleic acids encoding the compositions and vectors and host cells containing the same, and methods of making and using such compositions in treatment of factor VIII-related diseases, disorders, and conditions.
    Type: Application
    Filed: February 2, 2012
    Publication date: January 17, 2013
    Applicant: Amunix Operating Inc.
    Inventors: Volker Schellenberger, Pei-Yun Chang, Fatbardha Varfaj, John Kulman, Tongyao Liu, Garabet G. Toby, Haiyan Jiang, Robert Peters, Deping Wang, Baisong Mei, Joshua Silverman, Chia-Wei Wang, Benjamin Spink, Nathan Geething
  • Monoclonal Antibodies Against Tissue Factor Pathway Inhibitor
    Publication number: 20120269817
    Abstract: Isolated monoclonal antibodies that bind human tissue factor pathway inhibitor (TFPI) and the isolated nucleic acid molecules encoding them are provided. Pharmaceutical compositions comprising the anti-TFPI monoclonal antibodies and methods of treating deficiencies or defects in coagulation by administration of the antibodies are also provided. Methods of producing the antibodies are also provided.
    Type: Application
    Filed: August 4, 2009
    Publication date: October 25, 2012
    Applicant: BAYER HEALTHCARE LLC
    Inventors: Zhuozhi Wang, John E. Murphy, Junliang Pan, Haiyan Jiang, Bing Liu
  • Method for the Treatment of Hemophilia
    Publication number: 20120027743
    Abstract: The present invention is directed to a method for the treatment of hemophilia.
    Type: Application
    Filed: November 3, 2009
    Publication date: February 2, 2012
    Applicant: BAYER HEALTHCARE LLC
    Inventors: Haiyan Jiang, Tongyao Liu, Xin Zhang
  • FVIII Muteins for Treatment of Von Willebrand Disease
    Publication number: 20110286988
    Abstract: This invention relates to treatment of von Willebrand Disease by administration of Factor VIII muteins that are covalently bound, at a predefined site that is not an N-terminal amine, to one or more biocompatible polymers such as polyethylene glycol. The mutein conjugates retain FVIII procoagulant activity and have improved pharmacokinetic properties in subjects lacking von Willebrand Factor.
    Type: Application
    Filed: June 4, 2009
    Publication date: November 24, 2011
    Applicant: BAYER HEALTHCARE LLC
    Inventors: Haiyan Jiang, Glenn Pierce, John E. Murphy, Junliang Pan, Xin Zhang, Tongyao Liu
  • Targeted Coagulation Factors and Method of Using the Same
    Publication number: 20110077202
    Abstract: Targeted coagulation factors comprising a coagulation factor linked with at least one domain that specifically binds to a membrane protein on a blood cell is provided. The disclosed targeted coagulation factors increase the efficiency of coagulation factors and prolong their duration of action and thus, are an improvement for the treatment of hematological diseases such as hemophilia A.
    Type: Application
    Filed: May 15, 2009
    Publication date: March 31, 2011
    Applicant: BAYER HEALTHCARE LLC
    Inventors: Richard Feldman, Ji-Yun Kim, Haiyan Jiang, Kirk Mclean, Junliang Pan, Glenn Pierce, James Wu, Xiao-Yan Zhao
  • HUMAN ANTI-AMYLOID ANTIBODIES, COMPOSITIONS, METHODS AND USES
    Publication number: 20100074901
    Abstract: The present invention relates to at least one novel human anti-amyloid antibody, including isolated nucleic acids that encode at least one anti-amyloid antibody, amyloid, vectors, host cells, transgenic animals or plants, and methods of making and using thereof, including therapeutic compositions, methods and devices.
    Type: Application
    Filed: October 15, 2008
    Publication date: March 25, 2010
    Inventors: Marc Hubert Mercken, Jacqueline M. Benson, Sun-Yung S. Jung, Haiyan Jiang, Gopalan Raghunathan, Lionella Borozdina-Birch