Patents by Inventor Haiyan Liu
Haiyan Liu has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 8815900Abstract: Compositions comprising extracts or isolated or purified compounds from plants of the genus Corydalis provide prevention and treatment of hyperlipidemia, hypercholesterolemia, hypertriglyceridemia, hepatic steatosis, and metabolic syndrome. Corydalis compounds and their derivatives of natural and synthetic origins lower total cholesterol, LDL-cholesterol, and triglycerides and increase hepatic LDL receptor expression and activate AMP-activated protein kinase. Specific stereoisomers of Corydalis compounds with lipid lowering activity include 14R-(+)-corypalmine, 14R,13S-(+)-corydaline, 14R-(+)-tetrahydropalmatin, (+)-corlumidin, d-(+)-bicuculline, and (+)-egenine.Type: GrantFiled: July 11, 2011Date of Patent: August 26, 2014Assignee: CVI Pharmaceuticals LimitedInventors: Haiyan Liu, Junbo Wang, Rui Zhang, Nicholas Cairns, Jingwen Liu
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Patent number: 8710071Abstract: The present technology relates to compounds of Formulas (V) and methods of making and using such compounds. Methods of use include prevention and treatment of hyperlipidemia, hypercholesterolemia, hypertriglyceridemia, hepatic steatosis, and metabolic syndrome. Compounds disclosed herein also lower total cholesterol, LDL-cholesterol, and triglycerides and increase hepatic LDL receptor expression, inhibit PCSK9 expression, and activate AMP-activated protein kinase.Type: GrantFiled: December 22, 2009Date of Patent: April 29, 2014Assignee: CVI Pharmaceuticals LimitedInventors: Haiyan Liu, Gaoping Li, Junbo Wang, Jingwen Liu
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Patent number: 8643156Abstract: A lead frame has a flag, a peripheral frame, and main tie bars coupling the flag to the peripheral frame. At least one cross tie bar extends between two of the main tie bars and an inner row of external connector pads extending from an inner side of the cross tie bar and an outer row of external connector pads extending from an outer side of the cross tie bar. Both an inner non-electrically conductive support bar and an outer non-electrically conductive support bar are attached across the two of the main tie bars. The inner non-electrically conductive support bar is attached to upper surfaces of the two of the main tie bars and to upper surfaces of the inner row of the external connector pads.Type: GrantFiled: September 6, 2012Date of Patent: February 4, 2014Assignee: Freescale Semiconductor, Inc.Inventors: Shunan Qiu, Zhigang Bai, Haiyan Liu
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Publication number: 20140024199Abstract: A method of producing semiconductor dies includes providing a semiconductor wafer having front and back faces and an array of integrated circuits fabricated on it. The integrated circuits having active faces at the front face of the wafer. Grooves are cut mechanically from the back face partially through the wafer along saw streets between the integrated circuits. The integrated circuits are then singulated by scanning a laser beam on the front face within and along the saw streets, which scribes the wafer from the front face, and then singulating the integrated circuits by mechanically cleaving the wafer along the saw streets.Type: ApplicationFiled: November 19, 2012Publication date: January 23, 2014Inventors: Shunan QIU, Guoliang GONG, Jun LI, Haiyan LIU
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Patent number: 8603324Abstract: The present invention relates to a method of hydro-upgrading inferior gasoline through ultra-deep desulfurization and octane number recovery. The method comprises the following steps: cutting inferior full-range gasoline into light fraction gasoline and heavy fraction gasolines; contacting the light fraction gasoline successively with a catalyst for selective diene removal and a catalyst for desulfurization and hydrocarbon multi-branched-chain hydroisomerization; contacting the heavy fraction gasoline with the catalyst for selective hydrodesulfurization in a first reactor, and contacting the reaction effluent from the first reactor with a catalyst for supplemental desulfurization and hydrocarbon aromatization/single-branched-chain hydroisomerization in a second reactor; and blending the treated light fraction gasoline and the heavy fraction gasoline to obtain the ultra-clean gasoline product.Type: GrantFiled: March 17, 2010Date of Patent: December 10, 2013Assignee: China University of Petroleum—Bejing (CUPB)Inventors: Yu Fan, Xiaojun Bao, Gang Shi, Haiyan Liu
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Patent number: 8597494Abstract: The present invention relates to a method for producing ultra-clean gasoline. The invention provides a method of hydro-upgrading inferior gasoline through deep desulfurization and octane number recovery, which comprises the following steps: cutting inferior full-range gasoline into the light and heavy fraction gasolines; contacting the light fraction gasoline successively with a catalyst for selective diene removal and a catalyst for desulfurization and hydrocarbon aromatization/single-branched-chain hydroisomerization; contacting the heavy fraction gasoline with a catalyst for selective hydrodesulfurization, and contacting the reaction effluent with a catalyst for supplemental desulfurization and hydrocarbon multi-branched-chain hydroisomerization; and blending the treated light and heavy fraction gasolines to obtain the ultra-clean gasoline product.Type: GrantFiled: March 17, 2010Date of Patent: December 3, 2013Assignee: China University of Petroleum—Beijing (CUPB)Inventors: Yu Fan, Xiaojun Bao, Gang Shi, Haiyan Liu
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Publication number: 20130234306Abstract: A lead frame has a flag, a peripheral frame, and main tie bars coupling the flag to the peripheral frame. At least one cross tie bar extends between two of the main tie bars and an inner row of external connector pads extending from an inner side of the cross tie bar and an outer row of external connector pads extending from an outer side of the cross tie bar. Both an inner non-electrically conductive support bar and an outer non-electrically conductive support bar are attached across the two of the main tie bars. The inner non-electrically conductive support bar is attached to upper surfaces of the two of the main tie bars and to upper surfaces of the inner row of the external connector pads.Type: ApplicationFiled: September 6, 2012Publication date: September 12, 2013Applicant: FREESCALE SEMICONDUCTOR, INC.Inventors: Shunan Qiu, Zhigang Bai, Haiyan Liu
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Publication number: 20120004223Abstract: The present technology relates to compounds of Formulas (V) and (VI) and methods of making and using such compounds. Methods of use include prevention and treatment of hyperlipidemia, hypercholesterolemia, hypertriglyceridemia, hepatic steatosis, and metabolic syndrome. Compounds disclosed herein also lower total cholesterol, LDL-cholesterol, and triglycerides and increase hepatic LDL receptor expression, inhibit PCSK9 expression, and activate AMP-activated protein kinase.Type: ApplicationFiled: December 22, 2009Publication date: January 5, 2012Inventors: Haiyan Liu, Gaoping Li, Junbo Wang, Jingwen Liu
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Publication number: 20110268911Abstract: The present invention describes a novel process for the conformal coating of polymer fibers on nonwoven substrates. This process is based on the modification of polymer fiber surfaces by controlling the degree of etching and oxidation, which improves adhesion of initiators to the surface and facilitates subsequent conformal polymer grafting. The modified fiber surfaces render new functionalities to the surface, such as increasing hydrophilicity, attaching ligands or changing surface energy. The invention includes the modified polymer fibers produced by the process described herein.Type: ApplicationFiled: June 10, 2009Publication date: November 3, 2011Applicants: NORTH CAROLINA STATE UNIVERSITY, PATHOGEN REMOVAL AND DIAGNOSTIC TECHNOLOGIES, INC.Inventors: Yong Zheng, Sumana Roy Chowdhury, Patrick Vasconcelos Gurgel, Haiyan Liu, Ruben G. Carbonell
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Publication number: 20110269754Abstract: Compositions comprising extracts or isolated or purified compounds from plants of the genus Corydalis provide prevention and treatment of hyperlipidemia, hypercholesterolemia, hypertriglyceridemia, hepatic steatosis, and metabolic syndrome. Corydalis compounds and their derivatives of natural and synthetic origins lower total cholesterol, LDL-cholesterol, and triglycerides and increase hepatic LDL receptor expression and activate AMP-activated protein kinase. Specific stereoisomers of Corydalis compounds with lipid lowering activity include 14R-(+)-corypalmine, 14R,13S-(+)-corydaline, 14R-(+)-tetrahydropalmatin, (+)-corlumidin, d-(+)-bicuculline, and (+)-egenine.Type: ApplicationFiled: July 11, 2011Publication date: November 3, 2011Inventors: Haiyan Liu, Junbo Wang, Rui Zhang, Nicholas Cairns, Jingwen Liu
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Patent number: 8003795Abstract: Compositions comprising extracts or isolated or purified compounds from plants of the genus Corydalis provide prevention and treatment of hyperlipidemia, hypercholesterolemia, hypertriglyceridemia, hepatic steatosis, and metabolic syndrome. Corydalis compounds and their derivatives of natural and synthetic origins lower total cholesterol, LDL-cholesterol, and triglycerides and increase hepatic LDL receptor expression and activate AMP-activated protein kinase. Specific stereoisomers of Corydalis compounds with lipid lowering activity include 14R-(+)-corypalmine, 14R,13S-(+)-corydaline, 14R-(+)-tetrahydropalmatin, (+)-corlumidin, d-(+)-bicuculline, and (+)-egenine.Type: GrantFiled: June 20, 2008Date of Patent: August 23, 2011Assignee: CVI Pharmaceuticals LimitedInventors: Haiyan Liu, Junbo Wang, Rui Zhang, Nicholas Cairns, Jingwen Liu
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Publication number: 20110009628Abstract: The present technology relates to compounds of Formulas I-VI and methods of making and using such compounds. Methods of use include prevention and treatment of hyperlipidemia, hypercholesterolemia, hypertriglyceridemia, hepatic steatosis, and metabolic syndrome. Compounds disclosed herein also increase HDL-C, lower total cholesterol, LDL-cholesterol, and triglycerides and increase hepatic LDL receptor expression, inhibit PCSK9 expression, and activate AMP-activated protein kinase.Type: ApplicationFiled: July 8, 2010Publication date: January 13, 2011Inventors: Haiyan Liu, Gaoping Li, Junbo Wang, Jingwen Liu
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Publication number: 20100236978Abstract: The present invention relates to a method of hydro-upgrading inferior gasoline through ultra-deep desulfurization and octane number recovery. The method comprises the following steps: cutting inferior full-range gasoline into light fraction gasoline and heavy fraction gasolines; contacting the light fraction gasoline successively with a catalyst for selective diene removal and a catalyst for desulfurization and hydrocarbon multi-branched-chain hydroisomerization; contacting the heavy fraction gasoline with the catalyst for selective hydrodesulfurization in a first reactor, and contacting the reaction effluent from the first reactor with a catalyst for supplemental desulfurization and hydrocarbon aromatization/single-branched-chain hydroisomerization in a second reactor; and blending the treated light fraction gasoline and the heavy fraction gasoline to obtain the ultra-clean gasoline product.Type: ApplicationFiled: March 17, 2010Publication date: September 23, 2010Applicant: CHINA UNIVERSITY OF PETROLEUM - BEIJING (CUPB)Inventors: Yu FAN, Xiaojun BAO, Gang SHI, Haiyan LIU
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Publication number: 20100236979Abstract: The present invention relates to a method for producing ultra-clean gasoline. The invention provides a method of hydro-upgrading inferior gasoline through deep desulfurization and octane number recovery, which comprises the following steps: cutting inferior full-range gasoline into the light and heavy fraction gasolines; contacting the light fraction gasoline successively with a catalyst for selective diene removal and a catalyst for desulfurization and hydrocarbon aromatization/single-branched-chain hydroisomerization; contacting the heavy fraction gasoline with a catalyst for selective hydrodesulfurization, and contacting the reaction effluent with a catalyst for supplemental desulfurization and hydrocarbon multi-branched-chain hydroisomerization; and blending the treated light and heavy fraction gasolines to obtain the ultra-clean gasoline product.Type: ApplicationFiled: March 17, 2010Publication date: September 23, 2010Applicant: CHINA UNIVERSITY OF PETROLEUM - BEIJING (CUPB)Inventors: Yu Fan, Xiaojun Bao, Gang Shi, Haiyan Liu
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Publication number: 20090048246Abstract: Compositions comprising extracts or isolated or purified compounds from plants of the genus Corydalis provide prevention and treatment of hyperlipidemia, hypercholesterolemia, hypertriglyceridemia, hepatic steatosis, and metabolic syndrome. Corydalis compounds and their derivatives of natural and synthetic origins lower total cholesterol, LDL-cholesterol, and triglycerides and increase hepatic LDL receptor expression and activate AMP-activated protein kinase. Specific stereoisomers of Corydalis compounds with lipid lowering activity include 14R-(+)-corypalmine, 14R,13S-(+)-corydaline, 14R-(+)-tetrahydropalmatin, (+)-corlumidin, d-(+)-bicuculline, and (+)-egenine.Type: ApplicationFiled: June 20, 2008Publication date: February 19, 2009Inventors: Haiyan Liu, Junbo Wang, Rui Zhang, Nicholas Cairns, Jingwen Liu
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Publication number: 20080176245Abstract: A quantitative PCR method has been developed for the simultaneous detection and quantitation of an agent in samples of biologically derived materials. Unlike conventional quantitative PCR detection methods, this assay allows for the detection of viable agents.Type: ApplicationFiled: February 4, 2008Publication date: July 24, 2008Inventors: Haiyan Liu, Anthony S. Lubiniecki, Shing H. Mai, Amy A. Murnane, Leonard T. Olszewski, Gerardo A. Zabata
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Patent number: 7122645Abstract: A quantitative PCR method has been developed for the simultaneous detection and quantitation of an agent in samples of biologically derived materials. Unlike conventional quantitative PCR detection methods, this assay allows for the detection of viable agents.Type: GrantFiled: March 27, 2001Date of Patent: October 17, 2006Assignee: SmithKline Beecham CorporationInventors: Haiyan Liu, Anthony S. Lubiniecki, Shing H. Mai, Amy A. Murnane, Leonard T. Olszewski, Gerardo A. Zapata
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Publication number: 20060084052Abstract: A quantitative PCR method has been developed for the simultaneous detection and quantitation of an agent in samples of biologically derived materials. Unlike conventional quantitative PCR detection methods, this assay allows for the detection of viable agents.Type: ApplicationFiled: November 29, 2005Publication date: April 20, 2006Inventors: Haiyan Liu, Anthony Lubiniecki, Shing Mai, Amy Murnane, Leonard Olszewski, Gerardo Zapata
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Publication number: 20030108864Abstract: A quantitative PCR method has been developed for the simultaneous detection and quantitation of an agent in samples of biologically derived materials. Unlike conventional quantitative PCR detection methods, this assay allows for the detection of viable agents.Type: ApplicationFiled: September 25, 2002Publication date: June 12, 2003Inventors: Haiyan Liu, Anthony S. Lubiniecki, Shing H. Mai, Amy A. Murnane, Leonard T. Olszewski, Gerardo A. Zapata