Patents by Inventor Hajime Takashima
Hajime Takashima has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20230374034Abstract: A compound of the formula (I): wherein each symbol is as defined in the DESCRIPTION, or a pharmaceutically acceptable salt thereof has a superior Notch signal transduction inhibitory action, and is useful for preventing or treating various diseases involving Notch signal transduction.Type: ApplicationFiled: October 8, 2021Publication date: November 23, 2023Applicant: PRISM BIOLAB CO., LTD.Inventors: Hiroyuki KOUJI, Atsushi YOSHIMORI, Takenao ODAGAMI, Yoichiro HIROSE, Masaji KASHAI, Hajime TAKASHIMA, Eiji HONDA
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Publication number: 20230265104Abstract: A compound of the formula (I): wherein each symbol is as defined in the DESCRIPTION, or a pharmaceutically acceptable salt thereof has a superior inhibitory activity on cancer cell proliferation.Type: ApplicationFiled: July 16, 2021Publication date: August 24, 2023Applicant: PRISM BIOLAB CO., LTD.Inventors: Hajime TAKASHIMA, Eiji HONDA, Tomonori TAGURI, Jun OZAWA, Haruyuki NISHIDA, Yoichiro HIROSE, Keisuke KIMURA
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Patent number: 11435109Abstract: A ventilator includes a heat exchanger including a plurality of layered partition members, and a housing that has a first end wall part covering one end side of the heat exchanger along a layering direction and a second end wall part covering the other end side of the heat exchanger, and partitions a periphery of the heat exchanger into an exhaust air flow inlet space, an exhaust air flow outlet space, a supply air flow inlet space, and a supply air flow outlet space. An exhaust air flow passes through the exhaust air flow outlet space during heat exchange ventilation, and passes through the supply air flow inlet space during normal ventilation. A supply air flow passes through the supply air flow inlet space during heat exchange ventilation, and passes through the exhaust air flow outlet space during normal ventilation.Type: GrantFiled: March 24, 2017Date of Patent: September 6, 2022Assignee: MITSUBISHI ELECTRIC CORPORATIONInventors: Kohei Hasegawa, Hajime Takashima
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Publication number: 20220002279Abstract: The present invention provides a new imidazole derivative represented by the following formula or a pharmaceutically acceptable salt thereof which exhibits potent antimicrobial activity based on a LpxC-inhibiting action against gram-negative bacteria such as Pseudomonas aeruginosa, Escherichia coli, and Klebsiella pneumoniae, and their drug-resistant strains. General formula [1] or [2].Type: ApplicationFiled: November 20, 2019Publication date: January 6, 2022Applicant: TAISHO PHARMACEUTICAL CO., LTD.Inventors: Hajime TAKASHIMA, Yohei MATSUDA, Yuya OGATA, Naoki SASAMOTO, Risa TSURUTA, Fumihito USHIYAMA, Kaori UEKI, Nozomi TANAKA
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Publication number: 20190368769Abstract: A ventilator includes a heat exchanger including a plurality of layered partition members, and a housing that has a first end wall part covering one end side of the heat exchanger along a layering direction and a second end wall part covering the other end side of the heat exchanger, and partitions a periphery of the heat exchanger into an exhaust air flow inlet space, an exhaust air flow outlet space, a supply air flow inlet space, and a supply air flow outlet space. An exhaust air flow passes through the exhaust air flow outlet space during heat exchange ventilation, and passes through the supply air flow inlet space during normal ventilation. A supply air flow passes through the supply air flow inlet space during heat exchange ventilation, and passes through the exhaust air flow outlet space during normal ventilation.Type: ApplicationFiled: March 24, 2017Publication date: December 5, 2019Applicant: Mitsubishi Electric CorporationInventors: Kohei HASEGAWA, Hajime TAKASHIMA
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Patent number: 9499477Abstract: Provided is a novel compound which is useful as a pharmaceutical composition by inhibiting an LpxC activity, thereby exhibiting potent antimicrobial activity against gram-negative bacteria including Pseudomonas aeruginosa and its drug resistant bacteria. Provided is a hydroxamic acid derivative represented by the following general formula [1] or a pharmaceutically acceptable salt thereof.Type: GrantFiled: April 21, 2015Date of Patent: November 22, 2016Assignees: TOYAMA CHEMICAL CO., LTD., TAISHO PHARMACEUTICAL CO., LTDInventors: Hajime Takashima, Risa Tsuruta, Tetsuya Yabuuchi, Yusuke Oka, Hiroki Urabe, Yoichiro Suga, Masato Takahashi, Fumito Uneuchi, Hironori Kotsubo, Muneo Shoji, Yasuko Kawaguchi
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Publication number: 20150225335Abstract: Provided is a novel compound which is useful as a pharmaceutical composition by inhibiting an LpxC activity, thereby exhibiting potent antimicrobial activity against gram-negative bacteria including Pseudomonas aeruginosa and its drug resistant bacteria.Type: ApplicationFiled: April 21, 2015Publication date: August 13, 2015Applicants: TAISHO PHARMACEUTICAL CO., LTD., TOYAMA CHEMICAL CO., LTD.Inventors: Hajime TAKASHIMA, Risa TSURUTA, Tetsuya YABUUCHI, Yusuke OKA, Hiroki URABE, Yoichiro SUGA, Masato TAKAHASHI, Fumito UNEUCHI, Hironori KOTSUBO, Muneo SHOJI, Yasuko KAWAGUCHI
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Patent number: 9073821Abstract: Provided is a novel compound which is useful as a pharmaceutical composition by inhibiting an LpxC activity, thereby exhibiting potent antimicrobial activity against gram-negative bacteria including Pseudomonas aeruginosa and its drug resistant bacteria.Type: GrantFiled: April 20, 2011Date of Patent: July 7, 2015Assignees: TAISHO PHARMACEUTICAL CO., LTD, TOYAMA CHEMICAL CO., LTD.Inventors: Hajime Takashima, Risa Tsuruta, Tetsuya Yabuuchi, Yusuke Oka, Hiroki Urabe, Yoichiro Suga, Masato Takahashi, Fumito Uneuchi, Hironori Kotsubo, Muneo Shoji, Yasuko Kawaguchi
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Patent number: 8687101Abstract: A solid-state imaging device includes pixel cells that are formed on a substrate having a first substrate surface side, on which light is irradiated, and a second substrate surface side, on which elements are formed, and separated by an adjacent cell group and an element separation layer for each of the pixel cells or with plural pixel cells as a unit. Each of the pixel cells has a first conductive well formed on the first substrate surface side and a second conductive well formed on the second substrate surface side. The first conductive well receives light from the first substrate surface side and has a photoelectric conversion function and a charge accumulation function for the received light. A transistor that detects accumulated charges in the first conductive well and has a threshold modulation function is formed in the second conductive well.Type: GrantFiled: January 12, 2012Date of Patent: April 1, 2014Assignee: Sony CorporationInventors: Isao Hirota, Kouichi Harada, Nobuhiro Karasawa, Yasushi Maruyama, Yoshikazu Nitta, Hiroyuki Terakago, Hajime Takashima, Hideo Nomura
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Publication number: 20130072677Abstract: Provided is a novel compound which is useful as a pharmaceutical composition by inhibiting an LpxC activity, thereby exhibiting potent antimicrobial activity against gram-negative bacteria including Pseudomonas aeruginosa and its drug resistant bacteria.Type: ApplicationFiled: April 20, 2011Publication date: March 21, 2013Applicants: TOYAMA CHEMICAL CO., LTD., TAISHO PHARMACEUTICAL CO., LTDInventors: Hajime Takashima, Risa Tsuruta, Tetsuya Yabuuchi, Yusuke Oka, Hiroki Urabe, Yoichiro Suga, Masato Takahashi, Fumito Uneuchi, Hironori Kotsubo, Muneo Shoji, Yasuko Kawaguchi
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Publication number: 20120113292Abstract: A solid-state imaging device includes pixel cells that are formed on a substrate having a first substrate surface side, on which light is irradiated, and a second substrate surface side, on which elements are formed, and separated by an adjacent cell group and an element separation layer for each of the pixel cells or with plural pixel cells as a unit. Each of the pixel cells has a first conductive well formed on the first substrate surface side and a second conductive well formed on the second substrate surface side. The first conductive well receives light from the first substrate surface side and has a photoelectric conversion function and a charge accumulation function for the received light. A transistor that detects accumulated charges in the first conductive well and has a threshold modulation function is formed in the second conductive well.Type: ApplicationFiled: January 12, 2012Publication date: May 10, 2012Applicant: SONY CORPORATIONInventors: Isao Hirota, Kouichi Harada, Nobuhiro Karasawa, Yasushi Maruyama, Yoshikazu Nitta, Hiroyuki Terakago, Hajime Takashima, Hideo Nomura
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Patent number: 8106983Abstract: A solid-state imaging device includes pixel cells that are formed on a substrate having a first substrate surface side, on which light is irradiated, and a second substrate surface side, on which elements are formed, and separated by an adjacent cell group and an element separation layer for each of the pixel cells or with plural pixel cells as a unit. Each of the pixel cells has a first conductive well formed on the first substrate surface side and a second conductive well formed on the second substrate surface side. The first conductive well receives light from the first substrate surface side and has a photoelectric conversion function and a charge accumulation function for the received light. A transistor that detects accumulated charges in the first conductive well and has a threshold modulation function is formed in the second conductive well.Type: GrantFiled: December 9, 2008Date of Patent: January 31, 2012Assignee: Sony CorporationInventors: Isao Hirota, Kouichi Harada, Nobuhiro Karasawa, Yasushi Maruyama, Yoshikazu Nitta, Hiroyuki Terakago, Hajime Takashima, Hideo Nomura
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Patent number: 7916199Abstract: A pixel includes a photodiode, an overflow circuit, a first sensing circuit, and a second sensing circuit. The first sensing circuit charges and discharges a cathode capacitance by a photocurrent flowing through a photodiode, and amplifies an obtained voltage by a source follower amplifier so as to be outputted to a data line. The second sensing circuit charges and discharged the cathode capacitance by the photocurrent flowing through the photodiode, and outputs electric charge stored in the cathode capacitance via the data line. A pixel circuit is configured so that a first mode in which the first sensing circuit becomes active and a second mode in which the second sensing circuit becomes active can be switched. The first mode and the second mode are switched according to an amount of light received by the photodiode included in each pixel circuit. Gain is controlled according to the amount of light received, in the first mode, and the storage time is controlled in the second mode.Type: GrantFiled: January 31, 2007Date of Patent: March 29, 2011Assignees: National University Corporation Nara, Institute of Science and Technology Sanyo Electric Co., Ltd.Inventors: Keiichiro Kagawa, Jun Ohta, Yugo Nose, Atsushi Wada, Hajime Takashima
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Patent number: 7745776Abstract: In a photo detecting apparatus, a first capacitance is caused by a photo detecting element and the first capacitance is charged or discharged by current flowing through the photo detecting element. A second capacitance is connected in parallel with the photo detecting element, and the second capacitance charges or discharges an electric charge overflowing from the first capacitance. A current control element is connected to a terminal of the second capacitance on a side where the electric charge flows in, and the current control element delivers a current to cancel part of an electric charge when the electric charge overflowing from the first capacitance is stored in the second capacitance.Type: GrantFiled: September 28, 2007Date of Patent: June 29, 2010Assignee: Sanyo Electric Co., Ltd.Inventors: Atsushi Wada, Kuniyuki Tani, Hajime Takashima
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Publication number: 20090153708Abstract: A solid-state imaging device includes pixel cells that are formed on a substrate having a first substrate surface side, on which light is irradiated, and a second substrate surface side, on which elements are formed, and separated by an adjacent cell group and an element separation layer for each of the pixel cells or with plural pixel cells as a unit. Each of the pixel cells has a first conductive well formed on the first substrate surface side and a second conductive well formed on the second substrate surface side. The first conductive well receives light from the first substrate surface side and has a photoelectric conversion function and a charge accumulation function for the received light. A transistor that detects accumulated charges in the first conductive well and has a threshold modulation function is formed in the second conductive well.Type: ApplicationFiled: December 9, 2008Publication date: June 18, 2009Applicant: Sony CorporationInventors: Isao Hirota, Kouichi Harada, Nobuhiro Karasawa, Yasushi Maruyama, Yoshikazu Nitta, Hiroyuki Terakago, Hajime Takashima, Hideo Nomura
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Publication number: 20090086071Abstract: A pixel includes a photodiode, an overflow circuit, a first sensing circuit, and a second sensing circuit. The first sensing circuit charges and discharges a cathode capacitance by a photocurrent flowing through a photodiode, and amplifies an obtained voltage by a source follower amplifier so as to be outputted to a data line. The second sensing circuit charges and discharged the cathode capacitance by the photocurrent flowing through the photodiode, and outputs electric charge stored in the cathode capacitance via the data line. A pixel circuit is configured so that a first mode in which the first sensing circuit becomes active and a second mode in which the second sensing circuit becomes active can be switched. The first mode and the second mode are switched according to an amount of light received by the photodiode included in each pixel circuit. Gain is controlled according to the amount of light received, in the first mode, and the storage time is controlled in the second mode.Type: ApplicationFiled: January 31, 2007Publication date: April 2, 2009Inventors: Keiichiro Kagawa, Jun Ohta, Yugo Nose, Atsushi Wada, Hajime Takashima
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Patent number: 7391004Abstract: A pixel circuit includes a first detector which amplifies a voltage obtained by charging and discharging a capacitance with a photocurrent flowing through a photo detecting element and then outputs it to a first data line, and a second detector which outputs an electric charge stored in the capacitance by the photocurrent, to a second data line. The pixel circuit operates in a first operation mode where the first detector is activated, a second operation mode where the second detector is activated and an initialization mode where the photo detecting element is initialized. With a first transistor turned on, the second detector outputs an electric charge stored in the capacitance in the second operation mode, and in the initialization mode a reset voltage set in the second data line is applied to the other end of the photo detecting element to initialize the photo detecting element.Type: GrantFiled: March 28, 2007Date of Patent: June 24, 2008Assignee: Sanyo Electric Co., Ltd.Inventors: Hajime Takashima, Kuniyuki Tani
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Patent number: 7370328Abstract: When parallel processing is executed by parallel computers composed of a host computer and a plurality of processors connected to the host computer through a common bus, there is provided a method of assigning jobs to respective processors with high efficiency. A job in which a ratio between a communication time and a calculation time is larger than a predetermined value or larger than a fraction of processors and a job in which a ratio between a communication time and a calculation time is smaller than a predetermined value or smaller than a fraction of processors can be alternately assigned to respective processors.Type: GrantFiled: April 25, 2002Date of Patent: May 6, 2008Assignees: Honda Motor Co., Ltd., Taisho Pharmaceutical Co., Ltd.Inventors: Sou Yamada, Shinjiro Inabata, Nobuaki Miyakawa, Hajime Takashima, Kunihiro Kitamura, Unpei Nagashima
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Publication number: 20080079044Abstract: In a photo detecting apparatus, a first capacitance is caused by a photo detecting element and the first capacitance is charged or discharged by current flowing through the photo detecting element. A second capacitance is connected in parallel with the photo detecting element, and the second capacitance charges or discharges an electric charge overflowing from the first capacitance. A current control element is connected to a terminal of the second capacitance on a side where the electric charge flows in, and the current control element delivers a current to cancel part of an electric charge when the electric charge overflowing from the first capacitance is stored in the second capacitance.Type: ApplicationFiled: September 28, 2007Publication date: April 3, 2008Applicant: SANYO ELECTRIC CO., LTD.Inventors: Atsushi WADA, Kuniyuki TANI, Hajime TAKASHIMA
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Publication number: 20080067325Abstract: A plurality of pixel circuits, provided with a plurality of photo detecting elements, respectively, cause photocurrent corresponding to an incident light. The pixel circuits are placed on intersections of a plurality of data lines and scanning lines, respectively. A second capacitance charges and discharges an electric charge overflowing from a first capacitance caused by the photo detecting element. Each second capacitance is shared by a plurality of pixel circuits. A plurality of pixel circuits sharing the second capacitance are controlled so that exposure periods of the pixel circuits do not overlap with one another.Type: ApplicationFiled: September 20, 2007Publication date: March 20, 2008Applicant: Sanyo Electric Co., Ltd.Inventors: Kuniyuki Tani, Hajime Takashima, Atsushi Wada