Abstract: A method for registration of whole body volume images comprises obtaining (210) of a first image and a second image, comprising water and fat whole body magnetic resonance image data. Bone tissue are identified (220), creating respective bone images. Water components are separated (230), generating respective water images based on absolute water content. Fat components are separated (240), generating respective fat images based on absolute fat content. The first image is registered (250) to the second image by deforming the first bone image according to a bone tissue deformation rule, deforming the first water image according to a water tissue deformation rule under constraints of the first bone image deformation and deforming the first fat image according to a fat tissue deformation rule under constraints of the first bone image and the deformation of said first water image. Also, a method for analyzing the registered images is provided.

Abstract: A method for registration of whole body volume images comprises obtaining (210) of a first image and a second image, comprising water and fat whole body magnetic resonance image data. Bone tissue are identified (220), creating respective bone images. Water components are separated (230), generating respective water images based on absolute water content. Fat components are separated (240), generating respective fat images based on absolute fat content. The first image is registered (250) to the second image by deforming the first bone image according to a bone tissue deformation rule, deforming the first water image according to a water tissue deformation rule under constraints of the first bone image deformation and deforming the first fat image according to a fat tissue deformation rule under constraints of the first bone image and the deformation of said first water image. Also, a method for analyzing the registered images is provided.

Abstract: A device for puncturing cortical bone. The device consists of a cannula and inside of it an axially movable needle. The distal end of the needle has an eccentrically shaped tip which, by drilling, forms a hole, larger than the outer diameter of the needle, through corticalis, whereupon the enclosing cannula can be inserted into the drilled hole. In this way the cannula's position in the bone is secured and the cannula functions as a fixed anchored guiding channel for further sampling or treatment.