Patents by Inventor Hakuji Matsumoto

Hakuji Matsumoto has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Thermostable DNA polymerase from Thermus thermophilus HB-8
    Patent number: 5413926
    Abstract: A DNA polymerase from Thermus thermophilus which retains at least 60% of its activity when placed at pH 8.0 and 85.degree. C. for 2 hours is disclosed. The DNA polymerase has a pH optimum of about 8.0, a temperature optimum of about 75.degree. C., a mass of about 85 to 95 kDa and an optimal saline concentration of about 20-60 mM NaCl.
    Type: Grant
    Filed: June 5, 1992
    Date of Patent: May 9, 1995
    Assignee: Toyo Boseki Kabushiki Kaisha
    Inventors: Tairo Oshima, Hitoshi Sakashita, Hakuji Matsumoto, Yoshihiko Maekawa
  • Method of producing a thermostable DNA polymerase from Thermus thermophilus
    Patent number: 5242818
    Abstract: A DNA polymerase with excellent thermostability is provided. The DNA polymerase retains at least about 60% of its activity when placed at pH 8.0 for 2 hours at 85.degree. C.
    Type: Grant
    Filed: June 5, 1992
    Date of Patent: September 7, 1993
    Assignee: Toyo Boseki Kabushiki Kaisha
    Inventors: Tairo Oshima, Hitoshi Sakashita, Hakuji Matsumoto, Yoshihiko Maekawa
  • Thermostable DNA polymerase thermus thermophilus and a method of producing the same
    Patent number: 5192674
    Abstract: A DNA polymerase with excellent thermostability is provided. The DNA polymerase retains at least about 60% of its activity when placed at pH 8.0 for 2 hours at 85.degree. C.
    Type: Grant
    Filed: August 24, 1989
    Date of Patent: March 9, 1993
    Assignee: Toyo Boseki Kabushiki Kaisha
    Inventors: Tairo Oshima, Hitoshi Sakashita, Hakuji Matsumoto, Yoshihiko Maekawa
  • Element for assaying rheumatoid factor quantitatively and method of assaying the same
    Patent number: 5124250
    Abstract: An element for assaying a rheumatoid factor quantitatively in biosamples, comprising a polyalkyl methacrylate solid carrier and serum albumin immobilized thereon, the serum albumin being immunologically bound with anti-albumin rabbit IgG, and a method of assaying a rheumatoid factor quantitatively by immunoglobulin class in which the element is reacted with the biosample, then the element-bound rheumatoid factor is reacted with enzyme-labeled anti-human IgG, enzyme-labeled anti-human IgM or enzyme-labeled anti-human IgA, and then the amount of the marker enzyme is determined.
    Type: Grant
    Filed: September 11, 1989
    Date of Patent: June 23, 1992
    Assignee: Toyo Boseki Kabushiki Kaisha
    Inventors: Mami Inada, Hakuji Matsumoto, Tsuneo Hanyu, Kyoichi Kano
  • Method for determination of hydrogen peroxide by chemiluminescence analysis
    Patent number: 4647532
    Abstract: A method for determination of hydrogen peroxide by chemiluminescence analysis which consists of reacting a sample containing hydrogen peroxide with an oxidizable non-fluorescent substance in the presence of an oxidizing catalyst to convert the non-fluorescent substance to a fluorescent substance, reacting the fluorescent substance with an oxalic acid di-ester and hydrogen peroxide in the presence of an inhibitor which inactivates the oxidizing catalyst, and then measuring the amount of light emission produced to determine the amount of hydrogen peroxide contained in the sample. Determination and enzyme immunoassay for a component other than hydrogen peroxide in a sample from living body and evaluation of bactericidal activity in phagocytosis of leukocytes by utilizing this method are also disclosed.
    Type: Grant
    Filed: March 22, 1985
    Date of Patent: March 3, 1987
    Assignee: Toyo Boseki Kabushiki Kaisha
    Inventors: Haruo Watanabe, Noboru Mitsuhida, Makoto Andoh, Hakuji Matsumoto