Patents by Inventor Halina Levchik

Halina Levchik has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Crystalline polymorphic forms of monosodium n-[-8-(2-hydroxybenzoyl)amino]caprylate
    Patent number: 11395809
    Abstract: The present invention relates to crystalline polymorphic forms of monosodium N-[8-(2-hydroxybenzoyl)amino] caprylate (“SNAC”), including two hydrates, a methanol solvate, and an ethanol solvate, of SNAC. More specifically, the present invention provide six polymorphic forms of SNAC (hereafter referred to as Forms I-V). The present invention also provides an amorphous form of SNAC.
    Type: Grant
    Filed: July 30, 2020
    Date of Patent: July 26, 2022
    Assignee: NOVO NORDISK NORTH AMERICA OPERATIONS A/S
    Inventors: Halina Levchik, Shingai Majuru, Brahma Singh, Jamila Harris
  • CRYSTALLINE POLYMORPHIC FORMS OF MONOSODIUM N-[-8-(2-HYDROXYBENZOYL)AMINO]CAPRYLATE
    Publication number: 20210177792
    Abstract: The present invention relates to crystalline polymorphic forms of monosodium N-[8-(2-hydroxybenzoyl)amino] caprylate (“SNAC”), including two hydrates, a methanol solvate, and an ethanol solvate, of SNAC. More specifically, the present invention provide six polymorphic forms of SNAC (hereafter referred to as Forms I-V). The present invention also provides an amorphous form of SNAC.
    Type: Application
    Filed: July 30, 2020
    Publication date: June 17, 2021
    Inventors: Halina Levchik, Shingai Majuru, Brahma Singh, Jamila Harris
  • Crystalline polymorphic forms of monosodium N-[-8-(2-hydroxybenzoyl)amino]caprylate
    Patent number: 10744105
    Abstract: The present invention relates to crystalline polymorphic forms of monosodium N-[8-(2-hydroxybenzoyl)amino]caprylate (“SNAC”), including two hydrates, a methanol solvate, and an ethanol solvate, of SNAC. More specifically, the present invention provide six polymorphic forms of SNAC (hereafter referred to as Forms I-VI). The present invention also provides an amorphous form of SNAC.
    Type: Grant
    Filed: December 6, 2018
    Date of Patent: August 18, 2020
    Assignee: Emisphere Technologies, Inc.
    Inventors: Halina Levchik, Shingai Majuru, Brahma Singh, Jamila Harris
  • CRYSTALLINE POLYMORPHIC FORMS OF MONOSODIUM N-[-8-(2-HYDROXYBENZOYL)AMINO]CAPRYLATE
    Publication number: 20190343786
    Abstract: The present invention relates to crystalline polymorphic forms of monosodium N-[8-(2-hydroxybenzoyl)amino]caprylate (“SNAC”), including two hydrates, a methanol solvate, and an ethanol solvate, of SNAC. More specifically, the present invention provide six polymorphic forms of SNAC (hereafter referred to as Forms I-VI). The present invention also provides an amorphous form of SNAC.
    Type: Application
    Filed: December 6, 2018
    Publication date: November 14, 2019
    Inventors: Halina Levchik, Shingai Majuru, Brahma Singh, Jamila Harris
  • Crystalline polymorphic forms of monosodium N-[-8-(2-hydroxybenzoyl)amino]caprylate
    Patent number: 10188621
    Abstract: The present invention relates to crystalline polymorphic forms of monosodium N-[8-(2-hydroxybenzoyl)amino]caprylate (“SNAC”), including two hydrates, a methanol solvate, and an ethanol solvate, of SNAC. More specifically, the present invention provide six polymorphic forms of SNAC (hereafter referred to as Forms I-VI). The present invention also provides an amorphous form of SNAC.
    Type: Grant
    Filed: August 3, 2017
    Date of Patent: January 29, 2019
    Assignee: EMISPHERE TECHNOLOGIES, INC.
    Inventors: Halina Levchik, Shingai Majuru, Brahma Singh, Jamila Harris
  • PHARMACEUTICAL FORMULATIONS CONTAINING MICROPARTICLES OR NANOPARTICLES OF A DELIVERY AGENT
    Publication number: 20190022228
    Abstract: This invention relates to microparticles and/or nanoparticles containing a delivery agent and/or an active agent. This invention also relates to pharmaceutical formulations and solid dosage forms, including controlled release solid dosage forms of active agent and a delivery agent.
    Type: Application
    Filed: February 12, 2018
    Publication date: January 24, 2019
    Inventors: George Klein, Shingai Majuru, Puchun Liu, Steven Dinh, Jun Liao, Jongbin Lee, Halina Levchik, Ehud Arbit, Nikhil Dhoot, Jamila Harris, Nai Fang Wang
  • FORMULATIONS FOR DELIVERING INSULIN
    Publication number: 20180338923
    Abstract: Oral insulin formulations and processes for preparing oral insulin formulations are provided.
    Type: Application
    Filed: January 19, 2018
    Publication date: November 29, 2018
    Inventors: Halina LEVCHIK, Moses OYEWUMI, Shingai MAJURU, William E. BAY, Jun LIAO, Puchun LIU, Steven DINH, Nikhil DHOOT
  • CRYSTALLINE POLYMORPHIC FORMS OF MONOSODIUM N-[-8-(2-HYDROXYBENZOYL)AMINO]CAPRYLATE
    Publication number: 20170326087
    Abstract: The present invention relates to crystalline polymorphic forms of monosodium N-[8-(2-hydroxybenzoyl)amino] caprylate (“SNAC”), including two hydrates, a methanol solvate, and an ethanol solvate, of SNAC. More specifically, the present invention provide six polymorphic forms of SNAC (hereafter referred to as Forms I-VI). The present invention also provides an amorphous form of SNAC.
    Type: Application
    Filed: August 3, 2017
    Publication date: November 16, 2017
    Inventors: Halina Levchik, Shingai Majuru, Brahma Singh, Jamila Harris
  • Crystalline polymorphic forms of monosodium N-[-8-(2-hydroxybenzoyl)amino]caprylate
    Patent number: 9750710
    Abstract: The present invention relates to crystalline polymorphic forms of monosodium N-[8-(2-hydroxybenzoyl)amino]caprylate (“SNAC”), including two hydrates, a methanol solvate, and an ethanol solvate, of SNAC. More specifically, the present invention provide six polymorphic forms of SNAC (hereafter referred to as Forms I-VI). The present invention also provides an amorphous form of SNAC.
    Type: Grant
    Filed: February 22, 2016
    Date of Patent: September 5, 2017
    Assignee: Emisphere Technologies, Inc.
    Inventors: Halina Levchik, Shingai Majuru, Brahma Singh, Jamila Harris
  • CRYSTALLINE POLYMORPHIC FORMS OF MONOSODIUM N-[-8-(2-HYDROXYBENZOYL)AMINO]CAPRYLATE
    Publication number: 20160184251
    Abstract: The present invention relates to crystalline polymorphic forms of monosodium N-[8-(2-hydroxybenzoyl)amino]caprylate (“SNAC”), including two hydrates, a methanol solvate, and an ethanol solvate, of SNAC. More specifically, the present invention provide six polymorphic forms of SNAC (hereafter referred to as Forms I-VI). The present invention also provides an amorphous form of SNAC.
    Type: Application
    Filed: February 22, 2016
    Publication date: June 30, 2016
    Inventors: Halina LEVCHIK, Shingai MAJURU, Brahma SINGH, Jamila HARRIS
  • Crystalline polymorphic forms of monosodium N-[-8-(2-hydroxybenzoyl)amino]caprylate
    Patent number: 9321719
    Abstract: The present invention relates to crystalline polymorphic forms of monosodium N-[8-(2-hydroxybenzoyl)amino]caprylate (“SNAC”), including two hydrates, a methanol solvate, and an ethanol solvate, of SNAC. More specifically, the present invention provide six polymorphic forms of SNAC (hereafter referred to as Forms I-VI). The present invention also provides an amorphous form of SNAC.
    Type: Grant
    Filed: December 23, 2013
    Date of Patent: April 26, 2016
    Assignee: EMISPHERE TECHNOLOGIES, INC.
    Inventors: Halina Levchik, Shingai Majuru, Brahma Singh, Jamila Harris
  • FORMULATIONS FOR DELIVERING INSULIN
    Publication number: 20150190344
    Abstract: Oral insulin formulations and processes for preparing oral insulin formulations are provided.
    Type: Application
    Filed: January 5, 2015
    Publication date: July 9, 2015
    Inventors: Halina LEVCHIK, Moses Oyewumi, Shingai Majuru, William E. Bay, Jun Liao, Puchun Liu, Steven Dinh, Nikhil Dhoot
  • Formulations for delivering insulin
    Patent number: 8927015
    Abstract: Oral insulin formulations and processes for preparing oral insulin formulations are provided.
    Type: Grant
    Filed: April 12, 2007
    Date of Patent: January 6, 2015
    Assignee: Emisphere Technologies, Inc.
    Inventors: Halina Levchik, Moses O. Oyewumi, Shingai Majuru, William Elliott Bay, Jun Liao, Puchun Liu, Steven Dinh, Nikhil Dhoot
  • CRYSTALLINE POLYMORPHIC FORMS OF MONOSODIUM N-[-8-(2-HYDROXYBENZOYL)AMINO]CAPRYLATE
    Publication number: 20140187813
    Abstract: The present invention relates to crystalline polymorphic forms of monosodium N-[8-(2-hydroxybenzoyl)amino]caprylate (“SNAC”), including two hydrates, a methanol solvate, and an ethanol solvate, of SNAC. More specifically, the present invention provide six polymorphic forms of SNAC (hereafter referred to as Forms I-VI). The present invention also provides an amorphous form of SNAC.
    Type: Application
    Filed: December 23, 2013
    Publication date: July 3, 2014
    Applicant: Emisphere Technologies, Inc.
    Inventors: Halina LEVCHIK, Shingai Majuru, Brahma Singh, Jamila Harris
  • Crystalline polymorphic forms of monosodium N-[-8-(2-hydroxybenzoyl)amino]caprylate
    Patent number: 8636996
    Abstract: The present invention relates to crystalline polymorphic forms of monosodium N-[8-(2-hydroxybenzoyl)amino]caprylate (“SNAC”), including two hydrates, a methanol solvate, and an ethanol solvate, of SNAC. More specifically, the present invention provide six polymorphic forms of SNAC (hereafter referred to as Forms I-VI). The present invention also provides an amorphous form of SNAC.
    Type: Grant
    Filed: May 6, 2005
    Date of Patent: January 28, 2014
    Assignee: Emisphere Technologies, Inc
    Inventors: Halina Levchik, Shingai Majuru, Brahma Singh, Jamila Harris
  • PHARMACEUTICAL FORMULATIONS CONTAINING MICROPARTICLES OR NANOPARTICLES OF A DELIVERY AGENT
    Publication number: 20120189666
    Abstract: This invention relates to microparticles and/or nanoparticles containing a delivery agent and/or an active agent. This invention also relates to pharmaceutical formulations and solid dosage forms, including controlled release solid dosage forms of active agent and a delivery agent.
    Type: Application
    Filed: November 23, 2011
    Publication date: July 26, 2012
    Applicant: Emisphere Technologies, Inc.
    Inventors: Nikhil Dhoot, Halina Levchik, Shingai Majuru, George Klein, Jamila Harris, Puchun Liu, Steven Dinh, Jun Liao, Jongbin Lee, Ehud Arbit, Nai Fang Wang
  • FORMULATIONS FOR DELIVERING INSULIN
    Publication number: 20100151009
    Abstract: Oral insulin formulations and processes for preparing oral insulin formulations are provided.
    Type: Application
    Filed: April 12, 2007
    Publication date: June 17, 2010
    Applicant: Emisphere Technologies Inc.
    Inventor: Halina Levchik
  • PHARMACEUTICAL FORMULATIONS CONTAINING MICROPARTICLES OR NANOPARTICLES OF A DELIVERY AGENT
    Publication number: 20100055194
    Abstract: This invention relates to microparticles and/or nanoparticles containing a delivery agent and/or an active agent. This invention also relates to pharmaceutical formulations and solid dosage forms, including controlled release solid dosage forms of active agent and a delivery agent.
    Type: Application
    Filed: August 28, 2009
    Publication date: March 4, 2010
    Applicant: Emisphere Technologies, Inc.
    Inventors: Shingai Majuru, Puchun Liu, Steven Dinh, Jun Liao, Jongbin Lee, Ehud Arbit, Nikhil Dhoot, Halina Levchik, George Klein, Jamila Harris, Nai Fang Wang
  • Crystalline Polymorphic Forms Of Monosodium N-[-8-(2-Hydroxybenzoyl)Amino]Caprylate
    Publication number: 20090143330
    Abstract: The present invention relates to crystalline polymorphic forms of monosodium N-[8-(2-hydroxybenzoyl)amino] caprylate (“SNAC”), including two hydrates, a methanol solvate, and an ethanol solvate, of SNAC. More specifically, the present invention provide six polymorphic forms of SNAC (hereafter referred to as Forms I-VI). The present invention also provides an amorphous form of SNAC.
    Type: Application
    Filed: May 6, 2005
    Publication date: June 4, 2009
    Applicant: Emisphere Technologies, Inc.
    Inventors: Halina Levchik, Shingai Majuru, Brahma Singh, Jamila Harris
  • Polymorphs of sodium 4-[(4-chloro-2-hydroxybenzoyl) amino]butanoate
    Patent number: 7462368
    Abstract: The present invention relates to amorphous and polymorphic forms of sodium 4-[(4-chloro-2-hydroxybenzoyl)amino]butanoate and their use for facilitating the delivery of active agents, such as insulin, to a target.
    Type: Grant
    Filed: March 14, 2007
    Date of Patent: December 9, 2008
    Assignee: Emisphere Technologies, Inc.
    Inventors: Satej Bhandarkar, Shingai Majuru, Halina Levchik