Abstract: The present invention relates to a fully synthetic albumin analog, to a hemocompatible coating for medical devices containing the fully synthetic albumin analog, as well as to medical devices coated with the hemocompatible coating. The albumin analog preferably has two basic structures which are connected with one another via at least one bridging unit, the basic structures respectively having, in a geometrically defined manner, at least two bound joint regions to which at least one residue is covalently bound, wherein the basic structures are, respectively, a benzene carboxylic acid, and wherein the joint regions are formed via acid amide bonds, and wherein each residue, respectively, comprises a lipophilic region and a hydrophilic region.

Abstract: The present invention relates to a fully synthetic albumin analog, to a hemocompatible coating for medical devices containing the fully synthetic albumin analog, as well as to medical devices coated with the hemocompatible coating. The albumin analog preferably has two basic structures which are connected with one another via at least one bridging unit, the basic structures respectively having, in a geometrically defined manner, at least two bound joint regions to which at least one residue is covalently bound, wherein the basic structures are, respectively, a benzene carboxylic acid, and wherein the joint regions are formed via acid amide bonds, and wherein each residue, respectively, comprises a lipophilic region and a hydrophilic region.

Abstract: A multilayer filter medium (6) is used for separating precipitates containing cholesterol from blood plasma which consists of at least one open filter medium (7) which adsorbs precipitate and of a microporous membrane (9) which controls the pressure conditions in the filter element, whereby the layer (7) which specifically adsorbs the precipitate is hydrophobic and the microporous membrane (9) is hydrophilic. In addition, a positively charged adsorption medium (9) is provided on the side of the microporous membrane (8) facing away from the hydrophobic adsorption medium (7). In this manner, a large adsorption area is created and kept accessible for the precipitates and for heparin.

Abstract: Novel pyrrol-1-ylphenyldihydropyridazinones of the formula ##STR1## their preparation and their use in the treatment of disorders.

Abstract: Novel 6-(acylaminoaryl)-3(2H)-pyridazinones of the formula ##STR1## where R.sup.1, R.sup.2, R.sup.3, R.sup.4, A and B have the meanings given in the description, and their preparation are described and inhibiting thrombocyte aggregation and gastric secretion.The compounds are useful for treating disorders.

Abstract: Biologically active material such as an enzyme is bonded to a carrier containing hydroxyl groups by binding an isocyanate compound to the carrier and bonding the biologically active material to the bound isocyanate compound. Binding of the isocyanate compound to the carrier is achieved with the use of a non-toxic titanium based compound which catalyzes the formation of urethane bonds. The preferred non-toxic based titanium compound is an orthotitanium acid ester such as tetrabutyltitanate.

Abstract: A process is disclosed for removing urea from blood wash fluids or blood fluids in which the fluids are treated with an organic solid containing at least one proton-containing secondary substituent group which masks and activates the aldehyde group and the fluids and the solid organic compound are separated.

Abstract: Polyurethane molding compositions are disclosed which contain diisocyanates and polyols and/or polyurethane prepolymers and sorbic acid or cinnamic as a setting catalyst. A process for preparing such compositions is also disclosed. These compositions give a rapid initial hardening and therefore mold release properties, which contribute to increased production speeds. Moreover, the acids used are physiologically safe, so that the process may be used for the production of objects used in medical science. The acids may also be used in a physiologically safe mixture with a heavy-metal containing catalyst.

Abstract: Processes and apparatus for the removal of waste metabolites from metabolite-containing solutions are disclosed. The disclosed processes include alternatively adsorbing and desorbing the metabolites on a pair of adsorbent-containing columns, each column being maintained at a reduced temperature during adsorption and at an elevated temperature during desorption, with the columns being flushed subsequent to desorption and prior to their re-use for adsorption thereon.

Abstract: Columns for the treatment of a liquid with particulate material are disclosed comprising first and second layers of sheet material in face-to-face contact with each other, an inlet and an outlet located at points between the layers, and welds or the like for joining the layers together along a pair of substantially parallel paths between the inlet and the outlet in order to form an elongated space adapted to be filled with particulate material therebetween.

Abstract: A column for removing poisons and/or other undesired substances from a liquid mixture. The column has a mixture of inactive filler particles and active granules positioned therein, with said filler particles being substantially larger than said active granules, (which are selected from adsorbing material and ion-exchanging material). The filler particles are in fixed contact relationship with each other and the active granules completely fill the spaces between the filler particles.