Patents by Inventor Hans-Joachim Josef Gaus

Hans-Joachim Josef Gaus has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Chloral-free DCA in oligonucleotide synthesis
    Patent number: 7759480
    Abstract: A process of manufacturing oligonucleotides includes a 5?-deblocking step in which the 5-blocking group is removed with dichloroacetic acid that is essentially free of chloral. The process is useful for making oligonucleotides that are substantially free of chloral adducts.
    Type: Grant
    Filed: January 29, 2007
    Date of Patent: July 20, 2010
    Assignee: Isis Pharmaceuticals, Inc.
    Inventors: Achim Krotz, Daniel C. Capaldi, Hans-Joachim Josef Gaus, Brett Turney
  • Compounds and methods for the characterization of oligonucleotides
    Patent number: 7427675
    Abstract: The present invention relates to oligonucleotide synthesis. In particular, the present invention provides methods for characterizing samples useful for making oligonucleotides.
    Type: Grant
    Filed: August 22, 2005
    Date of Patent: September 23, 2008
    Assignee: Isis Pharmaceuticals, Inc.
    Inventors: Daniel C. Capaldi, Hans-Joachim Josef Gaus, Claus Andre Frank Rentel, Philip Dmitri Olsen, Christine C. Kurata, Quanlai Song