Patents by Inventor Hans Joerg Fehling

Hans Joerg Fehling has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Targeting the Rosa26 gene in human embryonic stem cells
    Patent number: 9062122
    Abstract: The invention provides a method for generating a transgenic eukaryotic cell population having a modified human Rosa26 locus, which method includes introducing a functional DNA sequence into the human Rosa26 locus of starting eukaryotic cells. Also provided are targeting vectors useful in the method, as well as a cell population and a transgenic non-human animal comprising a modified human Rosa26 locus. Finally, the invention provides an isolated DNA sequence corresponding to the human Rosa26 locus.
    Type: Grant
    Filed: January 18, 2008
    Date of Patent: June 23, 2015
    Assignee: MOUNT SINAI SCHOOL OF MEDICINE OF NEW YORK UNIVERSITY
    Inventors: Gordon Keller, Stefan Irion, Herve Luche, Paul Gadue, Hans Joerg Fehling
  • Cell population enriched for endoderm cells
    Patent number: 8748171
    Abstract: The present invention provides cell populations that are enriched for mesendoderm and mesoderm, and cell populations that are enriched for endoderm. The cell populations of the invention are useful for generating cells for cell replacement therapy.
    Type: Grant
    Filed: July 14, 2010
    Date of Patent: June 10, 2014
    Assignee: Mount Sinai School of Medicine
    Inventors: Gordon M Keller, Valerie Kouskoff, Atsushi Kubo, Hans Joerg Fehling
  • DEFINITIVE ENDODERM CELL POPULATIONS
    Publication number: 20120114613
    Abstract: The present invention provides cell populations that are enriched for mesendoderm and mesoderm, and cell populations that are enriched for endoderm. The cell populations of the invention are useful for generating cells for cell replacement therapy.
    Type: Application
    Filed: July 14, 2010
    Publication date: May 10, 2012
    Applicant: MOUNT SINAI SCHOOL OF MEDICINE OF NEW YORK UNIVERSITY
    Inventors: GORDON M. KELLER, VALERIE KOUSKOFF, ATSUSHI KUBO, HANS JOERG FEHLING
  • Method of enriching a mammalian cell population for mesoderm cells
    Patent number: 7955849
    Abstract: The present invention provides cell populations that are enriched for mesendoderm and mesoderm, and cell populations that are enriched for endoderm. The cell populations of the invention are useful for generating cells for cell replacement therapy.
    Type: Grant
    Filed: March 24, 2008
    Date of Patent: June 7, 2011
    Assignee: Mount Sinai School of Medicine
    Inventors: Gordon M. Keller, Valerie Kouskoff, Atsushi Kubo, Hans Joerg Fehling
  • MESENDODERM AND MESODERM CELL POPULATIONS
    Publication number: 20110070203
    Abstract: The present invention provides cell populations that are enriched for mesendoderm and mesoderm, and cell populations that are enriched for endoderm. The cell populations of the invention are useful for generating cells for cell replacement therapy.
    Type: Application
    Filed: July 14, 2010
    Publication date: March 24, 2011
    Applicant: Mount Sinai School of Medicine of New York University
    Inventors: Gordon M. Keller, Valerie Kouskoff, Atsushi Kubo, Hans Joerg Fehling
  • Mesoderm and definitive endoderm cell populations
    Patent number: 7763466
    Abstract: The present invention provides cell populations that are enriched for mesendoderm and mesoderm, and cell populations that are enriched for endoderm. The cell populations of the invention are useful for generating cells for cell replacement therapy.
    Type: Grant
    Filed: May 19, 2003
    Date of Patent: July 27, 2010
    Assignee: Mount Sinai School of Medicine of New York University
    Inventors: Gordon M. Keller, Valerie Kouskoff, Atsushi Kubo, Hans Joerg Fehling
  • STEM CELL GENE TARGETING
    Publication number: 20100011455
    Abstract: The invention provides a method for generating a transgenic eukaryotic cell population having a modified human Rosa26 locus, which method includes introducing a functional DNA sequence into the human Rosa26 locus of starting eukaryotic cells. Also provided are targeting vectors useful in the method, as well as a cell population and a transgenic non-human animal comprising a modified human Rosa26 locus. Finally, the invention provides an isolated DNA sequence corresponding to the human Rosa26 locus.
    Type: Application
    Filed: January 18, 2008
    Publication date: January 14, 2010
    Applicant: Mount Sinai School of Medicine of New York Univers
    Inventors: Gordon Keller, Stefan Irion, Herve Luche, Paul Gadue, Hans Joerg Fehling
  • Mesoderm and definitive endoderm cell populations
    Publication number: 20080226558
    Abstract: The present invention provides cell populations that are enriched for mesendoderm and mesoderm, and cell populations that are enriched for endoderm. The cell populations of the invention are useful for generating cells for cell replacement therapy.
    Type: Application
    Filed: March 24, 2008
    Publication date: September 18, 2008
    Applicant: Mount Sinai School of Medicine of New York University
    Inventors: Gordon M. Keller, Valerie Kouskoff, Atsushi Kubo, Hans Joerg Fehling