Patents by Inventor Hans John Hansen

Hans John Hansen has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Methods of antibody-directed enzyme-prodrug therapy
    Publication number: 20030068322
    Abstract: A method for targeting a therapeutic agent to a target site in a patient is provided.
    Type: Application
    Filed: November 5, 2002
    Publication date: April 10, 2003
    Applicant: IMMUNOMEDICS, INC.
    Inventor: Hans John Hansen
  • Method for antibody targeting of therapeutic agents
    Patent number: 5851527
    Abstract: The targeting capability of an antibody is enhanced using an antibody-enzyme conjugate and a separate soluble substrate-agent conjugate, wherein the targeted enzyme catalyzes the conversion of a soluble substrate, bearing at least one therapeutic or diagnostic agent, to a product comprising the agent, which accumulates at the target site for effective treatment or diagnosis. This method is useful for targeting any type of agent to a site to which an antibody can selectively bind, including use for imaging, e.g., tumors, infectious lesions, fibrin clots, myocardial infarctions, non-cancerous cells, damaged normal cells, atherosclerotic plaque, lymphocyte autoreactive clones, and for therapy, e.g., with drugs, toxins, immune modulators, radioisotopes or antibiotics.
    Type: Grant
    Filed: May 19, 1995
    Date of Patent: December 22, 1998
    Assignee: Immunomedics, Inc.
    Inventor: Hans John Hansen
  • Treatment of infectious and inflammatory lesions
    Patent number: 5705158
    Abstract: A polyspecific anti-leukocyte antibody conjugate for targeting foci of leukocyte accretion comprises an immunoreactive polyspecific composite of at least two different substantially monospecific antibodies or antibody fragments, conjugated to at least one imaging agent, wherein at least two of said antibodies or antibody fragments specifically bind to different leukocyte cell types.A method for targeting an imaging agent to an inflammatory or infectious lesion comprises injecting a mammal parenterally with an effective amount for targeting of the above anti-leukocyte imaging conjugate.A therapeutic anti-leukocyte antibody-agent conjugate for targeting foci of leukocyte accretion comprises at least one immunoreactive substantially monospecific antibody or antibody fragment which specifically binds to at least one leukocyte cell type, conjugated to at least one therapeutic antimicrobial agent.
    Type: Grant
    Filed: June 6, 1995
    Date of Patent: January 6, 1998
    Assignee: Immunomedics, Inc.
    Inventors: Hans John Hansen, Milton David Goldenberg
  • Carcinoembryonic antigens
    Patent number: 4086217
    Abstract: Antigens associated with carcinomas and adenocarcinomas as well as methods for isolating, identifying and detecting them are disclosed.
    Type: Grant
    Filed: February 18, 1977
    Date of Patent: April 25, 1978
    Assignee: Hoffmann-La Roche Inc.
    Inventor: Hans John Hansen
  • Carcinoembryonic antigens
    Patent number: 3956258
    Abstract: Antigens associated with carcinomas and adenocarcinomas as well as methods for isolating, identifying and detecting them are disclosed.
    Type: Grant
    Filed: May 13, 1974
    Date of Patent: May 11, 1976
    Assignee: Hoffmann-La Roche Inc.
    Inventor: Hans John Hansen