Patents by Inventor Hans Kosak

Hans Kosak has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20110046205
    Abstract: The invention relates to a method for dissolving charged nucleic acids in an organic first liquid which is immiscible with water. The method comprises the following steps: a) providing a solution of the nucleic acids in an aqueous second liquid, b) precipitating the nucleic acids by adding a complexing agent to the second liquid, the complexing agent forming complexes with the nucleic acids that are insoluble in the second liquid, c) removing the complexes from the second liquid, d) dissolving the complexes in a third liquid which consists of an amphiphilic compound or which contains an amphiphilic compound, and e) mixing the third liquid with the first liquid.
    Type: Application
    Filed: August 16, 2007
    Publication date: February 24, 2011
    Inventors: Hans Kosak, Andre Josten
  • Patent number: 7276369
    Abstract: The invention relates to a method for detecting an analyte A in a liquid, comprising the following steps: (a) a solution containing an analytical reagent N is provided in a container B; (b) the analyte A is added to the solution, (c) an electrical field eF which acts upon the solution is applied by means of electrodes disposed outside the container B, whereby a modification occurs in the concentration of a substance which is specific with respect to the presence of the analyte A in a region M of the container B and (d) the modification of said concentration is optically detected.
    Type: Grant
    Filed: May 29, 2002
    Date of Patent: October 2, 2007
    Inventor: Hans Kosak
  • Publication number: 20070048194
    Abstract: The invention relates to the use of a disposable container comprising a cylindcr (1) containing a plunger (2, 24) that is displaceably guided in said cylinder and a connection (3) that is provided on a first end (E1) of the cylinder (1) lying opposite the plunger (2, 24), said container being designed to create a difference in pressure in a microfluidic device (13) to hold (6) an agent (F, P) for processing molecules and/or to act as a reaction vessel.
    Type: Application
    Filed: July 15, 2003
    Publication date: March 1, 2007
    Applicant: November Aktiengesellschaft
    Inventors: Jurgen Schulein, Bjoern Grassel, Juergen Krause, Roland Barten, Dirk Kuhlmeier, Joerg Hassmann, Hans Kosak
  • Publication number: 20060222569
    Abstract: The present invention relates to a device, a kit and a method for the contamination-free preparation of analyte, in particular biopolymer comprising liquids. The device comprises wo chambers (2, 3) having a reversibly changeable volume.
    Type: Application
    Filed: April 19, 2004
    Publication date: October 5, 2006
    Inventors: Roland Barten, Jurgen Krause, Hans Kosak
  • Publication number: 20060024674
    Abstract: The invention relates to a method for conducting the parallel identification of different nucleic acids S. When nucleic acids S are present, primers are lengthened each of which having an intermediate segment z. The intermediate segment z is amplified by using a second primer pair and is specifically identified by hybridizing with a probe So.
    Type: Application
    Filed: November 13, 2003
    Publication date: February 2, 2006
    Applicant: November Aktiengesellschaft
    Inventors: Ronald Barten, Dirk Kuhlmeier, Anja Weiland, Hans Kosak, Jorg Hassmann
  • Publication number: 20060011474
    Abstract: The invention relates to a device (17) for detecting an analyte in a liquid having a multitude of electrodes (15), which are insulated from one another while being arranged on a first side (12) of an electrically non-conductive plate (10) that is impermeable to the liquid. Said electrodes (15) have, at least in part, an analyte-specific coating or analyte-specific molecules. Electrical conductors that pass through the plate (10) can, from a second side (14) of the plate, be electrically contacted and individually discharged. The coating or the molecules has/have a specific affinity to the analytes or to a substance formed due to the presence of the analyte. In addition, the device has no leakages.
    Type: Application
    Filed: June 27, 2003
    Publication date: January 19, 2006
    Applicant: NOVEMBER AKTIENGESELLSCHAFT
    Inventors: Jurgen Schulein, Christine Kugler, Burcu Meric, Hans Kosak, Jorg Hassmann, Bjorn Grassl, Dirk Kuhlmeier
  • Publication number: 20050214532
    Abstract: The invention relates to a security thread for the forgery-proof marking of objects, comprising at least one fibre (F) with nucleic acid molecules (N) bonded with the one end thereof to a fibre suface and the fibre (F). The other end of the nucleic acid molecule (N) is free such that complementary nucleic acid molecules (N?) may bind to the nucleic acid molecule (N).
    Type: Application
    Filed: May 8, 2002
    Publication date: September 29, 2005
    Inventors: Hans Kosak, Andre Josten
  • Publication number: 20050214764
    Abstract: The invention relates to a method for identifying, quantifying and/or characterizing an analyte (10) contained in a first liquid. Said method is characterized by the following steps: a) bringing the analyte (10) into contact with a first probe (20) and with a second probe (22), each probe having an affinity to the analyte (20), and incubating the analyte. The affinity of the first probe (20) is effected by a specific affinity to at least one first binding site (12) of the analyte (20), and the incubating ensues under conditions under which the first probe (20), and the second probe (22) bind to the analyte (10).
    Type: Application
    Filed: March 4, 2003
    Publication date: September 29, 2005
    Inventors: Emil Palecek, Hans Kosak
  • Publication number: 20050106684
    Abstract: The invention relates to a method for carrying out a reaction in an unmoved liquid in a capillary which is open at at least one end, with gas bubbles forming in the liquid, with a detergent being added to the liquid for the purpose of changing at least one property of the gas bubbles which are being formed and with the capillary being arranged, or having been arranged, at at least an angle to the horizontal which is such that the gas bubbles in the capillary ascend to a surface of the liquid.
    Type: Application
    Filed: October 22, 2004
    Publication date: May 19, 2005
    Applicant: NOVEMBER AKTIENGESELLSCHAFT
    Inventors: Jorg Hassmann, Hans Kosak, Dirk Kuhlmeier, Jurgen Krause, Markus Neugebauer, Ugur Ulker
  • Publication number: 20040248117
    Abstract: The invention relates to a method for detecting an analyte A in a liquid, comprising the following steps: (a) a solution containing an analytical reagent N is provided in a container B; (b) the analyte A is added to the solution, (c) an electrical field eF which acts upon the solution is applied by means of electrodes disposed outside the container B, whereby a modification occurs in the concentration of a substance which is specific with respect to the presence of the analyte A in a region M of the container B and (d) the modification of said concentration is optically detected.
    Type: Application
    Filed: June 14, 2004
    Publication date: December 9, 2004
    Inventor: Hans Kosak
  • Publication number: 20040038427
    Abstract: The invention relates to a method for detecting and/or quantifying the binding of first molecules (16) to second molecules (18) affine therein. The inventive method comprises the following steps: a) providing a container (10), wherein the second molecules (18) are immobilized on a wall, b) contacting the second molecules (18) to a solution containing the first molecules (16), c) incubating the container (10) in such a way that the first molecules (16) bind to the second molecules (18) and build up on the wall and d) detecting the changes in concentration of the first molecules (16) in the solution by means of radiation without removing the solution from the container (10), whereby the solution is contained in said container (10).
    Type: Application
    Filed: August 27, 2003
    Publication date: February 26, 2004
    Inventors: Hans Kosak, Jurgen Krause
  • Publication number: 20040013872
    Abstract: The invention relates to a synthetic particle used for marking a substance. Said synthetic particle is comprised of a number of identification substances (10, 12), which exist in a solid form, and of at least one covering (16), which encloses at least one of the identification substances (10, 12). The identification substances (10, 12) are selected such that the synthetic particle (18) can be identified by simultaneously identifying the identification substances (10, 12) in one and the same identification method on the basis of non-optical properties of the identification substances (10, 12).
    Type: Application
    Filed: July 14, 2003
    Publication date: January 22, 2004
    Inventors: Wolf Bertling, Hans Kosak
  • Publication number: 20030186257
    Abstract: The invention relates to a method for identify a predetermined mark (32) applied on a solid body (30) and constituted by planar elements (10). The inventive method comprises the following steps: (a) binding first biopolymers to a first part of the planar elements (10) so as to produce a first predetermined partial pattern, (b) contacting the mark (32) with third biopolymers that have an affinity to the first biopolymers so that the first and the third biopolymers bind to one another, and (c) identifying the first partial pattern produced by the bound first and third biopolymers by detecting the bond between the first and the third bipolymers by means of a one-stop detection method.
    Type: Application
    Filed: November 12, 2002
    Publication date: October 2, 2003
    Inventors: Wolf Bertling, Hans Kosak, Andr?eacute; Josten, Georg Bauer, Harald Walter
  • Publication number: 20030173232
    Abstract: The invention relates to a method to increase the sensitivity of a carbon electrode for electrochemically detecting an analyte without electrochemically conditioning the carbon electrode, wherein the method comprises treating the carbon electrode with an ionic detergent which is in solution, wherein the detergent is not incorporated in a coating of the electrode.
    Type: Application
    Filed: December 19, 2002
    Publication date: September 18, 2003
    Inventors: Jurgen Schulein, Christine Kugler, Burcu Meric, Bjorn Grassl, Georg Bauer, Andre Josten, Hans Kosak, Jorg Hassmann
  • Patent number: 6583336
    Abstract: The present invention relates to a novel process for the production of transgenic organisms or transgenic cells, to transgenic orgaisms or transgenic cells obtainable by the process of the present invention, to the use of vectors comprising DNA encoding a recombination promoting enzymes for curing impairments caused by environmental influences in plants or plant cells and for gene therapy in mammals or mammalian cells, and to novel vectors.
    Type: Grant
    Filed: April 28, 1998
    Date of Patent: June 24, 2003
    Assignee: BASF Plant Science GmbH
    Inventors: Bernd Reiss, Hans Kosak, Manfred Klemm, Jeff Schell
  • Patent number: 6261809
    Abstract: The invention relates to a method for marking solid, liquid or gaseous substances, whereby the substance to be marked is provided with at least one synthetically produced nucleic acid sequence. Said nucleic acid sequence contains a first sequence section constructed with the 5′ terminal end, a second sequence comprised of at least two bases and connected to said nucleic acid sequence, and a third sequence section constructed with the 3′ terminal end and connected to the said nucleic acid sequence. In order to simplify the identification of the marking, the invention provides that a first primer group is used with a first primer section corresponding to the first sequence section and a second primer group is used with a third primer section corresponding to the third sequence section.
    Type: Grant
    Filed: March 3, 2000
    Date of Patent: July 17, 2001
    Assignee: november Aktiengesellschaft Gesellschaft fur Molekulare Medizin
    Inventors: Wolf Bertling, Hans Kosak