Abstract: Personalized printed products are produced in which at least one individually printed sheet is combined with conventionally printed sheets. A plurality of stacks of conventionally printed sheets are made available. In addition, a print material web is made available that contains individual sheet segments and respectively one marking based on information received from a database, or a roll is provided which contains a pre-printed material web containing the sheets segments with respective markings. The markings on the individual sheet segments are read out and information read from the markings is used for selective gathering of conventionally printed sheets that are needed for the personalize printed product. Following the readout of the markings, individually printed sheets are cut from the print material web.

Abstract: Personalized printed products are produced in which at least one individually printed sheet is combined with conventionally printed sheets. A plurality of stacks of conventionally printed sheets are made available. In addition, a print material web is made available that contains individual sheet segments and respectively one marking based on information received from a database, or a roll is provided which contains a pre-printed material web containing the sheets segments with respective markings. The markings on the individual sheet segments are read out and information read from the markings is used for selective gathering of conventionally printed sheets that are needed for the personalize printed product. Following the readout of the markings, individually printed sheets are cut from the print material web.

Abstract: A method for continuously joining at least two imbricated flows of flat printed products which are conveyed at equal speeds and spaced from one another, the method includes initially offsetting a first imbricated flow of flat printed products relative to a second imbricated flow of flat printed products so as to form a first lateral overlapping area of both imbricated flows, continuously lifting the printed products of both imbricated flows in the first lateral overlapping area until the lateral overlapping is eliminated, and lowering or dropping the printed products of both imbricated flows in the raised lateral overlapping area, so that partially a printed product of the first imbricated or the second imbricated flow comes to rest above the first or second imbricated flows above a printed product of the respectively other imbricated flow, whereby a single imbricated flow with a second overlapping area of the printed products is formed.

Abstract: A new cellulose excipient, UICEL-XL, suitable for use as a binder, filler, and/or disintegrant in the development of solid dosage forms is described. UICEL-XL incorporates a cross-linking agent which provides the excipient with a high degree of crystallinity, high water affinity, and a high specific surface area, thus providing good disintegration properties. UICEL-XL, however, also has the unique distinction of being an effective binder due to its high tensile strength.

Abstract: In the method for producing a particulate material (58) from an at least partially liquid material (35) containing a solvent and/or dispersant, this material (35) is atomized in a process chamber (21) into droplets which are frozen to particles (131) by contact with a freezing fluid. The particles (131) are then dried by freeze-drying in the or in another process chamber (22) having a filter (18) at the top. For the freeze-drying, cooled process gas is passed upward from below through the process chamber (22) and through the filter (18) in such a way that at least a substantial part of the particles (131) rest against the filter (18) at least for a substantial part of the freeze-drying taking place in the process chamber (22). This makes it possible to dry a batch of particles (131) in a short time.

Abstract: In the method for producing a particulate material (58) from an at least partially liquid material (35) containing a solvent and/or dispersant, this material (35) is atomized in a process chamber (21) into droplets which are frozen to particles (131) by contact with a freezing fluid. The particles (131) are then dried by freeze-drying in the or in another process chamber (22) having a filter (18) at the top. For the freeze-drying, cooled process gas is passed upward from below through the process chamber (22) and through the filter (18) in such a way that at least a substantial part of the particles (131) rest against the filter (18) at least for a substantial part of the freeze-drying taking place in the process chamber (22). This makes it possible to dry a batch of particles (131) in a short time.

Abstract: A device for delivering a medicament has a membrane (7) with at least one permeable area (7b) permeable to the medicament and a reservoir space (25) which contains a solvent and the medicament at least partially dissolved therein, An adjustable and/or deformable control element (7) is disposed on the side of the membrane (7) facing the reservoir space (25) with which the access of the medicament from the reservoir space (25) to at least one permeable area (7b) of the membrane (7) can be changed. In addition an electronic device (37) is provided with which the control element (17) can be automatically controlled via a motor (37). The device permits the periodic alteration of the delivery rate of the medicament which is advantageous in many cases.

Abstract: The area which is to be cleaned is intially subjected to a pulsating jet of a liquid which penetrates through the area and which liquid contains a cleaning agent. Thereafter the area is rinsed by a pulsating jet of water which also penetrates through the area. Accordingly, the dirt gets dissolved and a mechanical working of the respective area is achieved simultaneously with a rinsing away of the dirt. Immediately thereafter the now wet area is penetrated by a hot pressurized air jet such to achieve a driving away of the dampness and accordingly a complete drying. If necessary, above sequence is repeated. Due to the speedy drying a forming of rings at the cleaned area is prevented and it is immediately possible to see if a visually complete cleaning has been achieved.

Abstract: A vessel (1) contains a rotor disc (23) mounted for rotation around a vertical axis (17) and arranged to bound a processing space (31) disposed above it. The agglomeration and/or the coating of particles are accomplished by moving the particles by the rotation of the rotor disc (23) and by means of a gas, in particular air, passed upwardly through the processing space (31) and by spraying them with a liquid. The torque required for the rotation of the rotor disc (23) is continuously measured by means of a torque measuring member (75) disposed between the rotor disc (23) and the drive device (77) arranged to drive the same. The agglomeration and/or the coating operation is controlled on the basis of the time-dependent variation of the torque and/or of the first derivative of the same, and/or of a variable having relation to the torque and/or its derivative.

Abstract: The system for testing the diffusion behavior of a substance comprises a donor compartment detachably mounted on a holding member of a rotor, rotatably around a vertical axis, said donor compartment being bounded at its bottom by a membrane effective to separate the donor compartment from an acceptor compartment. The membrane comprises a flexible carrier of a bio-compatible, lifeless, light permeable material, on which cells constituting a monocellular layer have been cultivated, for example. By determining the time dependent variation of the quantity of a substance passing through the membrane by diffusion, it is possible to determine the coefficient of diffusion and/or the coefficient of permeability of the membrane and of the cell culture provided thereon. By suitable selection of the cells, conditions may be created that closely resemble those that occur during the absorption of the respective substance through the biophase of a living organism.

Abstract: The mass to be sprayed by the spray gun is stored in an airtight closed storage container. A cushion of pressurized air is generated above the level of the paint mass present in the storage container. This air cushion is fed by means of a manually operated piston pump projecting into the storage container. Accordingly, the mass to be sprayed and fed via the feed line extending to the spray gun is pressurized. Conclusively the feed line can be designed with a longer dimension, the mass to be sprayed can be more viscous and the distance in height between storage container and spray gun can be much larger.

Abstract: A particulate material containing particles to be agglomerated and/or provided with a coating is introduced in batches into a space bounded by a container, in which a gas, in particular air, is passed through the particles. The particles are set in motion, for instance by the gas, such as in whirling motion, to form a whirling, layer. The particles are wetted by means of a mixture consisting of a gas and the vapor of a wetting agent. This mixture is introduced into the space containing the particles, and cold gas and a mixture of warm gas and wetting agent are supplied for example, alternately. In this manner, the particles may be wetted uniformly and relatively fast, and held at a relatively low temperature. This is of considerable advantage when processing thermolabile materials.

Abstract: The particles of the particulate material to be dried are cooled before the drying operation proper, or in the initial phase thereof, to a temperature low enough to make the liquid to be extracted solidify. At least the drying operation proper is carried out in a space bounded by a container, in which a gas, more particularly air, is passed through the particles. While in said space, the particles are subjected to motion, for example, they are whirled by the gas to form a whirling layer. The temperature of the gas is adjusted to have at least a considerable part of the drying operation take place by sublimation, the heat energy required for the sublimiation being supplied to the particles at least in part by the gas passed through them. In this way, the particulate material may be dried with care and nevertheless in relatively large batches, and with limited time expenditure.