Abstract: This disclosure features chemical entities (e.g., a compound or a pharmaceutically acceptable salt, and/or hydrate, and/or cocrystal, and/or drug combination of the compound) that inhibit (e.g., antagonize) Stimulator of Interferon Genes (STING). Said chemical entities are useful, e.g., for treating a condition, disease or disorder in which increased (e.g., excessive) STING activation (e.g., STING signaling) contributes to the pathology and/or symptoms and/or progression of the condition, disease or disorder (e.g., cancer) in a subject (e.g., a human). This disclosure also features compositions containing the same as well as methods of using and making the same.

Abstract: This disclosure features chemical entities (e.g., a compound or a pharmaceutically acceptable salt, and/or hydrate, and/or cocrystal, and/or drug combination of the compound) that inhibit (e.g., antagonize) Stimulator of Interferon Genes (STING). Said chemical entities are useful, e.g., for treating a condition, disease or disorder in which increased (e.g., excessive) STING activation (e.g., STING signaling) contributes to the pathology and/or symptoms and/or progression of the condition, disease or disorder (e.g., cancer) in a subject (e.g., a human). This disclosure also features compositions containing the same as well as methods of using and making the same.

Abstract: In one aspect, compounds of Formula AA, or a pharmaceutically acceptable salt thereof, are featured: wherein the variables shown in Formula AA can be as defined anywhere herein.

Abstract: This disclosure relates to a semiconductor device including a device with high clamping voltage (HVC device), and an OTS device. Such a semiconductor device provides very advantageous ESD protection. The semiconductor device can be realized in two ways: an OTS device and a device with high clamping voltage can be realized as discrete, independent devices that are combined in one semiconductor package, or an OTS device can be integrated into interconnect layers of a device with high clamping voltage by integration.

Abstract: An electrostatic discharge (ESD), protection device is provided. In accordance with the present disclosure, an ESD protection device is provided that includes a series connection of a first unit having strong snapback and low series capacitance and a second high-voltage unit that displays a relatively high holding/trigger voltage to ensure latch up and improper triggering of the ESD protection device while at the same time providing high-voltage operation with low capacitive loading.

Abstract: A semiconductor device is provided that is useful for ESD protection purposes. The device includes a semiconductor die; diode unit cells integrated on the die and being electrically connected between the first and second terminal, each unit cell includes a first region of a first charge type in the die and a second region of a second charge type in the die; an isolation structure arranged in the die, the isolation structure being configured to electrically isolate the unit cells from one another in the semiconductor die; and contacts including first contacts that are electrically connected to the first terminal and second contacts that are electrically connected to the second terminal, and each contact among the first and second contacts is electrically connected to the first region of a respective unit cell among the unit cells and to the second region of another unit cell among the unit cells.

Abstract: A semiconductor device including an interconnect. The interconnect is arranged to transfer current from one terminal to another, and the interconnect includes a first layer including a plurality of interweaved fingers, and each of the interweaved fingers varies in width in a direction of propagation current thereby resulting in a difference of resistance within each of the interweaved fingers in the direction of propagation of current; a second layer arranged below the first layer. The second layer compensates for the difference of resistance in the first layer.

Abstract: A semiconductor device is provided including a die having an electronic component integrated thereon. The component includes regions in the die, including a first region of a first charge type electrically connected to a first device terminal, a second region of a second charge type forming a first PN junction with the first region, a third region of the first charge type forming a second PN junction with the second region, the third region being spaced apart from the first region by the second region and being electrically connected to the second device terminal, a fourth region of the first charge type forming a third PN junction with the second region, the fourth region being spaced apart from the first region and third region by the second region. The device further includes an electronic unit electrically connected between the first device terminal, the second device terminal and the fourth region.

Abstract: The present invention is directed to a gas detector configured to improve response speed of a gas sensor. A gas detector includes a housing, a gas sensor main body installed in the housing, and a partition wall provided in the housing and limiting the surrounding of the gas sensor main body to separate from the other area. The housing or the partition wall includes an opening portion directly connected from the outside to an area inside the partition wall.

Abstract: The invention relates to a new method of preparation of a polynuclear iron compound stabilized by carbohydrates and/or humic acid or forming a complex with carbohydrates and/or humic acid using a pressure-driven filtration process.

Abstract: A semiconductor device is provided that includes at least three regions. Each region includes a first-type layer doped with a first type of charge carriers and a second-type layer doped with a second type of charge carriers, and the first-type layer and the second-type layer are positioned laterally along each region. The first-type layer and the second-type layer have opposite polarity, and the first-type layer of a region is positioned substantially across the second-type layer of a neighboring region, and the second-type layer of a region is positioned substantially across the first-type layer of a neighboring region and each region includes a second-type well doped with the second type of charge carriers, and the second-type well is positioned around at least the first-type layer.

Abstract: This disclosure features chemical entities (e.g., a compound or a pharmaceutically acceptable salt, and/or hydrate, and/or cocrystal, and/or drug combination of the compound) that inhibit (e.g., antagonize) Stimulator of Interferon Genes (STING). Said chemical entities are useful, e.g., for treating a condition, disease or disorder in which increased (e.g., excessive) STING activation (e.g., STING signaling) contributes to the pathology and/or symptoms and/or progression of the condition, disease or disorder (e.g., cancer) in a subject (e.g., a human). This disclosure also features compositions containing the same as well as methods of using and making the same.

Abstract: A park release apparatus for shifting a transmission of a vehicle having an engine from park to neutral with the engine not running via a park release lever of the transmission, the apparatus including a transmission assembly configured for being selectively installed on the transmission spaced from the park release lever, a handle assembly, a cable assembly having a slidable cable operably connecting the transmission assembly and the handle assembly, and a release bracket coupled to the cable in the vicinity of the transmission assembly and configured for selectively engaging the park release lever.

Abstract: An electric motor, in particular for an electromechanical brake device of a vehicle, includes a stator and a multi-pole rotor with an odd number of rotor poles. Recesses are defined in the central region of the rotor poles, drive assembly, and electromechanical brake device for a vehicle.

Abstract: Systems, methods, and computer-readable media are disclosed for visual labeling of training data items for training a machine learning model. Training data items may be generated for training the machine learning model. Visual labels, such as QR codes, may be created for the training data items. The creation of the training data item and the visual label may be automated. The visual labels and the training data items may be combined to obtain a labeled training data item. The labeled training data item may comprise a separator to distinguish the training data item from the visual label. The labeled training data item may be used for training and validation of the machine learning model. The machine learning model may analyze the training data item, attempt to identify the training data item, and compare the identification against the embedded label.

Abstract: Systems, methods, and computer-readable media are disclosed for list attribute normalization and standardization for creation of a controlled vocabulary. A vocabulary set comprising a plurality of vocabulary term may be received. For each vocabulary term, semantic duplicates may be identified. The semantic duplicates may be identified by analyzing semantics, syntactics, or phonetics of the vocabulary terms. Semantic chains may be formed from each vocabulary term and the corresponding semantic duplicates. The terms in each semantic chain may be ranked to determine a most probable vocabulary term. The most probable vocabulary term may then replace the semantic chain. The most probable vocabulary term across all semantic chains from the vocabulary set may form the controlled vocabulary.

Abstract: A suction device may include a suction channel, a first valve, and a second valve. The suction channel may include a first suction portion and a second suction portion disposed opposite one another in a transverse direction. The first valve may be arranged in the first suction portion. The first valve may include a first valve seat and a moveable first valve body. The second valve may be arranged in the second suction portion. The second valve may include a second valve seat and a moveable second valve body. When a transverse acceleration is equal to or greater than a predefined transverse acceleration, one of the first valve and the second valve may close while the other one of the first valve and the second valve remains open. When the transverse acceleration is less than the predefined transverse acceleration, the first valve and the second valve may both be open.

Abstract: This disclosure features chemical entities (e.g., a compound or a pharmaceutically acceptable salt, and/or hydrate, and/or cocrystal, and/or drug combination of the compound) that inhibit (e.g., antagonize) Stimulator of Interferon Genes (STING). Said chemical entities are useful, e.g., for treating a condition, disease or disorder in which increased (e.g., excessive) STING activation (e.g., STING signaling) contributes to the pathology and/or symptoms and/or progression of the condition, disease or disorder (e.g., cancer) in a subject (e.g., a human). This disclosure also features compositions containing the same as well as methods of using and making the same.

Abstract: A gas sensor (1) is described comprising a light source (2), and a detector (4), a first reflector (7), which is concave and arranged to reflect and concentrate light emitted from the light source (2) to a first light spot (31), and an interference filter (5). The gas sensor comprises a second reflector (8), a third reflector (9), which is concave, and a reflector base (37) with a dome shaped surface (17) with the first and third reflectors facing the light source (2) and the detector (4). During operation of the gas sensor (1), the detector (4) is illuminated by light from the light source (2), which in an optical path from the light source (2) has been reflected at least once in each one of the first reflector (7), the second reflector (8), and the third reflector (9). The gas sensor (1) is configured for detection of a first wavelength portion of the light.

Abstract: This disclosure features chemical entities (e.g., a compound or a pharmaceutically acceptable salt, and/or hydrate, and/or cocrystal, and/or drug combination of the compound) that inhibit (e.g., antagonize) Stimulator of Interferon Genes (STING). Said chemical entities are useful, e.g., for treating a condition, disease or disorder in which increased (e.g., excessive) STING activation (e.g., STING signaling) contributes to the pathology and/or symptoms and/or progression of the condition, disease or disorder (e.g., cancer) in a subject (e.g., a human). This disclosure also features compositions containing the same as well as methods of using and making the same.