Patents by Inventor Hans-Peter Kley

Hans-Peter Kley has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Triazolophthalazines
    Patent number: 7671050
    Abstract: The compounds of formula (I) in which R1, R2 and R3 have the meanings as given in the description are novel effective PDE2 inhibitors.
    Type: Grant
    Filed: January 4, 2006
    Date of Patent: March 2, 2010
    Assignee: NYCOMED GmbH
    Inventors: Beate Schmidt, Steffen Weinbrenner, Dieter Flockerzi, Raimund Külzer, Hermann Tenor, Hans-Peter Kley
  • Novel 3-thia-10-aza-phenanthrene derivatives
    Publication number: 20090239895
    Abstract: The compounds of formula I in which A, R1, R2 and R3 have the meanings as given in the description, are novel effective PDE4 inhibitors.
    Type: Application
    Filed: May 28, 2009
    Publication date: September 24, 2009
    Applicant: Nycomed GmbH
    Inventors: Dieter Flockerzi, Ulrich Kautz, Armin Hatzelmann, Christof Zitt, Andrea Wohlsen, Degenhard Marx, Hans-Peter Kley, Jens Christoffers, Anna Rosiak
  • 3-thia-10-aza-phenanthrene derivatives
    Patent number: 7589205
    Abstract: The compounds of formula I in which A, R1, R2 and R3 have the meanings as given in the description, are novel effective PDE4 inhibitors.
    Type: Grant
    Filed: September 5, 2005
    Date of Patent: September 15, 2009
    Assignee: NYCOMED GmbH
    Inventors: Dieter Flockerzi, Ulrich Kautz, Armin Hatzelmann, Christof Zitt, Andrea Wohlsen, Degenhard Marx, Hans-Peter Kley, Jens Christoffers, Anna Rosiak
  • Triazolophthalazines
    Publication number: 20090005372
    Abstract: The compounds of formula I in which R1 and R2 have the meanings as given in the description are novel effective PDE2 inhibitors.
    Type: Application
    Filed: August 31, 2005
    Publication date: January 1, 2009
    Applicant: Altana Pharma AG
    Inventors: Beate Schmidt, Steffen Weinbrenner, Dieter Flockerzi, Raimund Kuelzer, Hermann Tenor, Hans-Peter Kley
  • Triazolophthalazines
    Publication number: 20080312225
    Abstract: The compounds of formula (I) in which R1, R2 and R3 have the meanings as given in the description are novel effective PDE2 inhibitors.
    Type: Application
    Filed: January 4, 2006
    Publication date: December 18, 2008
    Applicant: NYCOMED GMBH
    Inventors: Beate Schmidt, Steffen Weinbrenner, Dieter Flockerzi, Raimund Kulzer, Hermann Tenor, Hans-Peter Kley
  • Triazolophthalazines
    Publication number: 20080280907
    Abstract: The compounds of formula (I) in which R1, R2 and R3 have the meanings as given in the description are novel effective PDE2 inhibitors.
    Type: Application
    Filed: January 4, 2006
    Publication date: November 13, 2008
    Applicant: Aaltana Pharma AG
    Inventors: Beate Schmidt, Steffen Weinbrenner, Dieter Flockerzi, Raimund Kulzer, Hermann Tenor, Hans-Peter Kley
  • Combination of a NSAID and a PDE-4 inhibitor
    Publication number: 20080255209
    Abstract: The invention relates to the combined use of a PDE4 inhibitor and a conventional NSAID in the treatment of an inflammatory disease and/or an inflammation-associated disorder while minimizing gastrointestinal side effects, such as gastric erosions and ulcer, which are frequently associated with the use of conventional NSAIDs. A preferred PDE 4 inhibitor for this combination is roflumilast or a derivative thereof. A preferred conventional NSAID for this combination is diclofenac or a derivative thereof.
    Type: Application
    Filed: December 20, 2007
    Publication date: October 16, 2008
    Applicant: NYCOMED GMBH
    Inventors: Thomas Klein, Hans-Peter Kley
  • Roflumilast for the Treatment of Diabetes Mellitus
    Publication number: 20080214625
    Abstract: The invention relates to the use of Roflumilast and/or Roflumilast N-Oxide for the treatment of diabetes mellitus and accompanying disorders thereof. The invention additionally relates to combinations of Roflumilast and/or Roflumilast N-Oxide with other active agents for the treatment of diabetes mellitus.
    Type: Application
    Filed: March 3, 2006
    Publication date: September 4, 2008
    Applicant: KONINKLIJKE HILIPS ELECTRONICS, N.V.
    Inventors: Hans-Peter Kley, Guido Hanauer, Daniela Hauser, Beate Schmidt, Dirk Bredenbroker, Wilhelm Wurst, Jorg Kemkowski
  • Amido-Substituted 6-Phenylphenanthridines
    Publication number: 20080214536
    Abstract: Compounds of a certain formula (I) in which R1, R2, R3, R31, R4, R5, R51, R6 and R7 have the meanings indicated in the description, are novel effective PDE4 inhibitors.
    Type: Application
    Filed: March 9, 2006
    Publication date: September 4, 2008
    Applicant: NYCOMED Gmbh
    Inventors: Ulrich Kautz, Beate Schmidt, Dieter Flockerzi, Maria Vittoria Chiesa, Armin Hatzelmann, Christof Zitt, Johannes Barsig, Degenhard Marx, Hans-Peter Kley
  • 6-Heteroaryl-1,2,3,4,4A, 10B-Hexahydrophenanthridines as Pde4-Inhibitors for the Treatment of Inflammatory Disorders
    Publication number: 20080167316
    Abstract: Compounds of a certain formula I in which R1, R2, R3, R31, R4, R5, R51 and Har have the meanings indicated in the description, are novel effective PDE4 inhibitors.
    Type: Application
    Filed: March 1, 2006
    Publication date: July 10, 2008
    Applicant: Altana Pharma AG
    Inventors: Ulrich Kautz, Beate Schmidt, Dieter Flockerzi, Maria Vittoria Chiesa, Armin Hatzelmann, Christof Zitt, Adrea Wohlsen, Degenhard Marx, Hans-Peter Kley
  • Novel 6-Pyridylphenanthridines
    Publication number: 20080119505
    Abstract: Compounds of a certain formula (I), in which R1, R2, R3, R31, R4, R5, R51 and Har have the meanings indicated in the description, are novel effective PDE4 inhibitors.
    Type: Application
    Filed: January 31, 2006
    Publication date: May 22, 2008
    Applicant: ALTANA Pharma AG
    Inventors: Ulrich Kautz, Beate Schmidt, Dieter Flockerzi, Maria Vittoria Chiesa, Armin Hatzelmann, Christof Zitt, Johannes Barsig, Andrea Wohlsen, Degenhard Marx, Hans-Peter Kley
  • Novel 3-Thia-10-Aza-Phenanthrene Derivatives
    Publication number: 20080103168
    Abstract: The compounds of formula I in which A, R1, R2 and R3 have the meanings as given in the description, are novel effective PDE4 inhibitors.
    Type: Application
    Filed: September 5, 2005
    Publication date: May 1, 2008
    Applicant: Atlana Pharma AG
    Inventors: Dieter Flockerzi, Ulrich Kautz, Armin Hatzelmann, Christof Zitt, Andrea Wohlsen, Degenhard Marx, Hans-Peter Kley, Jens Christoffers, Anna Rosiak
  • Novel 3-Oxa-10-Aza-Phenanthrenes
    Publication number: 20070259868
    Abstract: The compounds of formula I in which R1, R2 and R3 have the meanings as given in the description, are novel effective PDE4 inhibitors.
    Type: Application
    Filed: September 5, 2005
    Publication date: November 8, 2007
    Applicant: Altana Pharma AG
    Inventors: Dieter Flockerzi, Ulrich Kautz, Armin Hatzelmann, Christof Zitt, Andrea Wohlsen, Degenhard Marx, Hans-Peter Kley, Jens Christoffers, Anna Rosiak
  • Use of pde4 inhibitors for the treatment of diabetes mellitus
    Publication number: 20060281745
    Abstract: The invention relates to the use of certain known PIDE4 inhibitors for the treatment of diabetes mellitus and accompanying disorders thereof.
    Type: Application
    Filed: September 2, 2004
    Publication date: December 14, 2006
    Applicant: Altana Pharma AG
    Inventor: Hans-Peter Kley
  • Combination
    Publication number: 20040242597
    Abstract: The invention relates to the combined administration of PDE4-inhibitors and NSAIDs for the treatment of an inflammatory disease and/or an inflammation associated disorder while minimizing gastrointesti-nal side effects, such as gastric erosions and ulcer, which are frequently associated with the use of NSAIDs.
    Type: Application
    Filed: March 18, 2004
    Publication date: December 2, 2004
    Inventors: Thomas Klein, Hans-Peter Kley
  • 3-cyclopropylmethoxy-4-difluoromethoxy-N-(3,5-dichloropyrid-4-yl)benzamide in the treatment of multiple sclerosis
    Patent number: 6531493
    Abstract: The invention relates to the novel use of 3-cyclopropylmethoxy-4-difluoromethoxy-N-(3,5-dichloropyrid-4-yl)benzamide, a pharmacologically tolerable salt thereof or its N-oxide in the treatment of multiple sclerosis.
    Type: Grant
    Filed: September 5, 2001
    Date of Patent: March 11, 2003
    Assignee: Altana Pharma AG
    Inventors: Hans-Peter Kley, Karl Sanders
  • Anti-depressant and analgesic 4-phenoxypiperidines
    Patent number: 4333942
    Abstract: 4-Phenoxypiperidines of the general formula I ##STR1## wherein R.sup.1 denotes a hydrogen atom, an alkyl group with 1 to 5 carbon atoms, an alkenyl group with 3 to 5 carbon atoms, a cycloalkylmethyl group with 3 to 7 carbon atoms in the cycloalkyl part or a phenylalkyl group with 1 to 3 carbon atoms in the alkyl part,R.sup.2 denotes a hydrogen atom, a nitro group, an amino group or an acylamino group andR.sup.3 denotes a phenyl group or a benzyl group,and their N-oxides and their acid-addition salts are new compounds. They have an antiptotic and analgesic action and are suitable for the treatment of depressions and painful conditions. Processes for the preparation of the new compounds are provided.
    Type: Grant
    Filed: July 11, 1980
    Date of Patent: June 8, 1982
    Assignee: BYK Gulden Lomberg Chemische Fabrik GmbH
    Inventors: Klaus Eistetter, Hans-Peter Kley, Heinz-Gunter Menge, Hartmann Schaefer
  • Substituted 1-phenyl-2-pyrrolidin-2-yl-ethanols, their synthesis, their use and their compositions
    Patent number: 4198424
    Abstract: Selected substituted 1-phenyl-2-pyrrolidin-2-yl-ethanols and their pharmacologically-acceptable acid-addition salts are useful as analgesics in human and veterinary medicine. Such compounds are prepared by reducing corresponding substituted 1-phenyl-2-pyrrolidin-2-yl ethanones and are formulated into medicinal compositions suitable for administration.
    Type: Grant
    Filed: November 30, 1978
    Date of Patent: April 15, 1980
    Assignee: Byk Gulden Lomberg Chemische Fabrik GmbH
    Inventors: Klaus Eistetter, Hans-Peter Kley