Abstract: Disclosed herein is a microfluidic device and a method for transporting and sampling a defined volume of plasma, providing a fluid passageway from an inlet to an outlet comprising a first region with the inlet with a first high flow resistance configured to receive and collect a whole blood sample and to separate plasma; and a second region with the outlet lower flow resistance. The second region is in fluid connection with the first region and configured to meter the separated plasma by comprising a metering channel.

Abstract: A device for measuring a component in exhaled breath comprising an inlet for receiving exhaled breath, a buffer chamber. A first fluid conduit is in fluid connection with the inlet and adapted to lead a first portion of the exhaled breath to the buffer chamber. The buffer chamber comprises an outlet for discarding a first part of exhaled breath received from the first fluid conduit and the buffer chamber is configured to buffer a second part of exhaled breath received from the first fluid conduit. The device comprises a second fluid conduit in fluid connection with the inlet and adapted to lead a second portion of the exhaled breath to be discarded, and a sensor for measuring a component in the exhaled breath buffered in the buffer chamber.

Abstract: A device for measuring a component in exhaled breath comprising an inlet (32) for receiving exhaled breath, a buffer chamber (31). A first fluid conduit (34a) is in fluid connection with the inlet and adapted to lead a first portion (?) of the exhaled breath to the buffer chamber. The buffer chamber comprises an outlet (37) for discarding a first part of exhaled breath received from the first fluid conduit and the buffer chamber is configured to buffer a second part of exhaled breath received from the first fluid conduit. The device comprises a second fluid conduit (34b) in fluid connection with the inlet and adapted to lead a second portion (I?) of the exhaled breath to be discarded, and a sensor (63) for measuring a component in the exhaled breath buffered in the buffer chamber.

Abstract: A device for measuring a component in exhaled breath comprising an inlet (32) for receiving exhaled breath, a buffer chamber (31). A first fluid conduit (34a) is in fluid connection with the inlet and adapted to lead a first portion (?) of the exhaled breath to the buffer chamber. The buffer chamber comprises an outlet (37) for discarding a first part of exhaled breath received from the first fluid conduit and the buffer chamber is configured to buffer a second part of exhaled breath received from the first fluid conduit. The device comprises a second fluid conduit (34b) in fluid connection with the inlet and adapted to lead a second portion (I?) of the exhaled breath to be discarded, and a sensor (63) for measuring a component in the exhaled breath buffered in the buffer chamber.

Abstract: A micromachined fluid flow regulating device is disclosed comprising a fluid flow channel, at least one flow orifice formed in the channel, defining an inlet portion of the channel upstream of the flow orifice, an outlet portion of the channel downstream of the flow orifice, the fluid having a flow direction from the inlet portion to the outlet portion of the channel. At least one piston is arranged upstream of the flow orifice, movably suspended in the channel by a spring means such that the piston is movable by the fluid in the flow direction of the fluid, towards the flow orifice, to regulate a fluid flow through the flow orifice. The disclosure further relates to the use of a micromachined flow regulating device in a breath analysis device and to a method of fabricating a flow regulating device.