Abstract: Erectile dysfunction in a male human patient is ameliorated by oral administration to the patient of prednisone followed by administration of sildenafil, preferably as sildenafil citrate.

Abstract: Erectile dysfunction in a male human patient is ameliorated by oral administration to the patient of a glucocorticoid such as prednisone, prednisolone, cortisone, hydrocortisone, or methylprednisolone and a phosphodiesterase type 5 (PDE5) inhibitor, such as sildenafil, vardenafil, or tadalafil.

Abstract: Erectile dysfunction in a male human patient is ameliorated by oral administration to the patient of a glucocorticoid such as prednisone, prednisolone, cortisone, hydrocortisone, or methylprednisolone and a phosphodiesterase type 5 (PDE5) inhibitor, such as sildenafil, vardenafil, or tadalafil.

Abstract: The present invention includes a composition for sterilizing a bioscaffold, comprising slightly acidic electrolyzed water (SAEW) as an active ingredient, and a method for sterilizing a bioscaffold using the same. The slightly acidic electrolyzed water according to the present invention has excellent effects on the sterilization of bioscaffolds and the removal of immunogenic antigens and a little effect on extracellular matrix, such as glycosaminoglycans or collagen. Moreover, the scaffold sterilized with the slightly acidic electrolyzed water has excellent cell attachment and has no toxicity, and thus the slightly acidic electrolyzed water can be effectively used for the sterilization of bioscaffolds.

Abstract: The present invention includes a composition for sterilizing a bioscaffold, comprising slightly acidic electrolyzed water (SAEW) as an active ingredient, and a method for sterilizing a bioscaffold using the same. The slightly acidic electrolyzed water according to the present invention has excellent effects on the sterilization of bioscaffolds and the removal of immunogenic antigens and a little effect on extracellular matrix, such as glycosaminoglycans or collagen. Moreover, the scaffold sterilized with the slightly acidic electrolyzed water has excellent cell attachment and has no toxicity, and thus the slightly acidic electrolyzed water can be effectively used for the sterilization of bioscaffolds.

Abstract: Erectile dysfunction in a male human patient is ameliorated by oral administration to the patient of a phosphodiesterase type 5 (PDE5) inhibitor, such as sildenafil, vardenafil, or tadalafil, and a glucocorticoid such as prednisone, prednisolone, cortisone, hydrocortisone, or methylprednisolone.

Abstract: Erectile dysfunction in a male human patient is ameliorated by oral administration to the patient of a phosphodiesterase type 5 (PDE5) inhibitor, such as sildenafil, and a glucocorticoid such as prednisone.

Abstract: Devices for treatment of congestive heart failure include devices insertable over and clamped on all or a selected portion of the exterior of a heart. The devices may be introduced surgically, or under thoracoscopic control around a portion or all of the exterior of the heart.

Abstract: Devices for treatment of congestive heart failure include devices insertable over and clamped on all or a selected portion of the exterior of a heart. The devices may be introduced surgically, or under thoracoscopic control around a portion or all of the exterior of the heart.

Abstract: A myocardial implant for insertion into a heart wall for trans myocardial revascularization (TMR) of the heart wall. The TMR implant provides for means to promote the formation of new blood vessels (angiogenesis), and has a flexible, elongated body that contains a cavity and openings through the flexible, elongated body from the cavity. The TMR implant includes a coaxial anchoring element integrally formed at one end for securing the TMR implant in the heart wall.

Abstract: A stent for insertion into a heart wall for Trans Myocardial Revascularization (TMR) thereof. The TMR stent provides for the delivery of blood nutrients from a heart chamber into the heart wall and has an elongated body which may contain a cavity and openings through the elongated body from the cavity. The elongated body should be in fluid communication with the heart chamber. If a cavity and openings are provided, the openings are in fluid communication with the heart chamber, the cavity and the heart wall. The TMR stent may include an anchoring element integrally formed thereon for securing the TMR stent in the heart wall.

Abstract: A medical device and method are described for performing Trans Myocardial Revascularization (TMR) in a human heart. The device consists of a myocardial implant and a directable intracardiac catherter that are suited for delivery into a heart wall of the implant. The catheter utilizes a percutaneous, minimally-invasive access to reach the inner surface of the heart chambers. The catheter provides a conduit for advancing multiple myocardial implants to the heart wall. The implant may include anchoring elements or a retainer for holding the implant body into the heart wall. The implant may include a tapered leading end, and can be advanced into the heart wall using a rotational or a pushing technique until the implant is fully deployed. The implant is then released from the catheter, and another implant inserted into the catheter, or the catheter withdrawn from the human body.

Abstract: A delivery device for insertion of a myocardial implant into a heart wall for trans myocardial revascularization (TMR) of the heart wall. The delivery device provides for the exact placement of one or more TMR implants into a heart wall, and has an elongated, tubular body that may include spaced-apart ports and a connecting conduit. A needle point is formed at one end to pierce the heart wall, and a handle is formed at another end to manipulate the device. The delivery device may include a surrounding sheath into which the needle point and a needle assembly may be withdrawn to release the TMR implant in the heart wall, and withdraw the delivery device from a person's body. The sheath may include a locking portion for holding the TMR implant in position when releasing the implant in a heart wall.

Abstract: A stent for insertion into a heart wall for Trans Myocardial Revascularization (TMR) thereof. The TMR stent provides for the delivery of blood nutrients from a heart chamber into the heart wall and has an elongated body which may contain a cavity and openings through the elongated body from the cavity. The elongated body should be in fluid communication with the heart chamber. If a cavity and openings are provided, the openings are in fluid communication with the heart chamber, the cavity and the heart wall. The TMR stent may include an anchoring element integrally formed thereon for securing the TMR stent in the heart wall.

Abstract: A stent for insertion into a heart wall for Trans Myocardial Revascularization (TMR) thereof. The TMR stent provides for the delivery of blood nutrients from a heart chamber into the heart wall and has an elongated body which may contain a cavity and openings through the elongated body from the cavity. The elongated body should be in fluid communication with the heart chamber. If a cavity and openings are provided, the openings are in fluid communication with the heart chamber, the cavity and the heart wall. The TMR stent may include an anchoring element integrally formed thereon for securing the TMR stent in the heart wall.