Patents by Inventor Hao-Wei Shih

Hao-Wei Shih has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • CRYSTALLINE 4-((L-VALYL)OXY)BUTANOIC ACID
    Publication number: 20240092727
    Abstract: Crystalline 4-((L-valyl)oxy)butanoic acid, methods of preparing crystalline 4-((L-valyl)oxy)butanoic acid, pharmaceutical compositions of crystalline 4-((L-valyl)oxy)butanoic acid, and methods of treatment using crystalline 4-((L-valyl)oxy)butanoic acid are disclosed.
    Type: Application
    Filed: August 29, 2023
    Publication date: March 21, 2024
    Inventors: JIA-NING XIANG, XUESONG XU, XUAN ZHANG, JAMES TIEN, HAO-WEI SHIH, HSIN-YI HUANG
  • METHODS OF SYNTHESIZING 4-VALYLOXYBUTYRIC ACID
    Publication number: 20230357130
    Abstract: The present disclosure is directed synthetic methods for the preparation of 4-valyloxybutyric acid. The synthetic methods described herein employ a diverse array of protecting group strategies and reaction conditions. Additionally, the present disclosure is directed to compounds useful as synthetic intermediates in the preparation of 4-valyloxybutyric acid.
    Type: Application
    Filed: July 12, 2023
    Publication date: November 9, 2023
    Inventors: JIA-NING XIANG, HAO-WEI SHIH, XIAOMING WU, XUAN ZHANG, JAMES TIEN
  • Methods of synthesizing 4-valyloxybutyric acid
    Patent number: 11746081
    Abstract: The present disclosure is directed synthetic methods for the preparation of 4-valyloxybutyric acid. The synthetic methods described herein employ a diverse array of protecting group strategies and reaction conditions. Additionally, the present disclosure is directed to compounds useful as synthetic intermediates in the preparation of 4-valyloxybutyric acid.
    Type: Grant
    Filed: February 16, 2022
    Date of Patent: September 5, 2023
    Assignee: XWPHARMA LTD.
    Inventors: Jia-Ning Xiang, Hao-Wei Shih, Xiaoming Wu, Xuan Zhang, James Tien
  • KETAMINE DERIVATIVES AND COMPOSITIONS THEREOF
    Publication number: 20220411365
    Abstract: Ketamine derivatives and pharmaceutical compositions thereof are disclosed. When administered orally the ketamine derivatives provide increased bioavailability of ketamine in the systemic circulation. The ketamine derivatives can be used to treat neurological diseases, psychological diseases and pain.
    Type: Application
    Filed: August 1, 2022
    Publication date: December 29, 2022
    Inventors: JIA-NING XIANG, XUESONG XU, HAO-WEI SHIH, WAI-SI ENG
  • Ketamine derivatives and compositions thereof
    Patent number: 11440874
    Abstract: Ketamine derivatives and pharmaceutical compositions thereof are disclosed. When administered orally the ketamine derivatives provide increased bioavailability of ketamine in the systemic circulation. The ketamine derivatives can be used to treat neurological diseases, psychological diseases and pain.
    Type: Grant
    Filed: October 12, 2020
    Date of Patent: September 13, 2022
    Assignee: XWPHARMA LTD.
    Inventors: Jia-Ning Xiang, Xuesong Xu, Hao-Wei Shih, Wai-Si Eng
  • METHODS OF SYNTHESIZING 4-VALYLOXYBUTYRIC ACID
    Publication number: 20220234994
    Abstract: The present disclosure is directed synthetic methods for the preparation of 4-valyloxybutyric acid. The synthetic methods described herein employ a diverse array of protecting group strategies and reaction conditions. Additionally, the present disclosure is directed to compounds useful as synthetic intermediates in the preparation of 4-valyloxybutyric acid.
    Type: Application
    Filed: February 16, 2022
    Publication date: July 28, 2022
    Inventors: JIA-NING XIANG, HAO-WEI SHIH, XIAOMING WU, XUAN ZHANG, JAMES TIEN
  • Methods of synthesizing 4-valyloxybutyric acid
    Patent number: 11279669
    Abstract: The present disclosure is directed synthetic methods for the preparation of 4-valyloxybutyric acid. The synthetic methods described herein employ a diverse array of protecting group strategies and reaction conditions. Additionally, the present disclosure is directed to compounds useful as synthetic intermediates in the preparation of 4-valyloxybutyric acid.
    Type: Grant
    Filed: June 18, 2021
    Date of Patent: March 22, 2022
    Assignee: XWPHARMA LTD.
    Inventors: Jia-Ning Xiang, Hao-Wei Shih, Xiaoming Wu, Xuan Zhang, James Tien
  • METHODS OF SYNTHESIZING 4-VALYLOXYBUTYRIC ACID
    Publication number: 20220055982
    Abstract: The present disclosure is directed synthetic methods for the preparation of 4-valyloxybutyric acid. The synthetic methods described herein employ a diverse array of protecting group strategies and reaction conditions. Additionally, the present disclosure is directed to compounds useful as synthetic intermediates in the preparation of 4-valyloxybutyric acid.
    Type: Application
    Filed: June 18, 2021
    Publication date: February 24, 2022
    Inventors: JIA-NING XIANG, HAO-WEI SHIH, XIAOMING WU, XUAN ZHANG, JAMES TIEN
  • KETAMINE DERIVATIVES AND COMPOSITIONS THEREOF
    Publication number: 20210032199
    Abstract: Ketamine derivatives and pharmaceutical compositions thereof are disclosed. When administered orally the ketamine derivatives provide increased bioavailability of ketamine in the systemic circulation. The ketamine derivatives can be used to treat neurological diseases, psychological diseases and pain.
    Type: Application
    Filed: October 12, 2020
    Publication date: February 4, 2021
    Applicant: XW LABORATORIES INC.
    Inventors: JIA-NING XIANG, XUESONG XU, HAO-WEI SHIH, WAI-SI ENG
  • Ketamine derivatives and compositions thereof
    Patent number: 10836714
    Abstract: Ketamine derivatives and pharmaceutical compositions thereof are disclosed. When administered orally the ketamine derivatives provide increased bioavailability of ketamine in the systemic circulation. The ketamine derivatives can be used to treat neurological diseases, psychological diseases and pain.
    Type: Grant
    Filed: April 2, 2020
    Date of Patent: November 17, 2020
    Assignee: XW LABORATORIES INC.
    Inventors: Jia-Ning Xiang, Xuesong Xu, Hao-Wei Shih, Wai-Si Eng
  • KETAMINE DERIVATIVES AND COMPOSITIONS THEREOF
    Publication number: 20200231540
    Abstract: Ketamine derivatives and pharmaceutical compositions thereof are disclosed. When administered orally the ketamine derivatives provide increased bioavailability of ketamine in the systemic circulation. The ketamine derivatives can be used to treat neurological diseases, psychological diseases and pain.
    Type: Application
    Filed: April 2, 2020
    Publication date: July 23, 2020
    Applicant: XW LABORATORIES INC.
    Inventors: JIA-NING XIANG, XUESONG XU, HAO-WEI SHIH, WAI-SI ENG
  • Ketamine derivatives and compositions thereof
    Patent number: 10683262
    Abstract: Ketamine derivatives and pharmaceutical compositions thereof are disclosed. When administered orally the ketamine derivatives provide increased bioavailability of ketamine in the systemic circulation. The ketamine derivatives can be used to treat neurological diseases, psychological diseases and pain.
    Type: Grant
    Filed: July 3, 2019
    Date of Patent: June 16, 2020
    Assignee: XW LABORATORIES INC.
    Inventors: Jia-Ning Xiang, Xuesong Xu, Hao-Wei Shih, Wai-si Eng
  • KETAMINE DERIVATIVES AND COMPOSITIONS THEREOF
    Publication number: 20190322618
    Abstract: Ketamine derivatives and pharmaceutical compositions thereof are disclosed. When administered orally the ketamine derivatives provide increased bioavailability of ketamine in the systemic circulation. The ketamine derivatives can be used to treat neurological diseases, psychological diseases and pain.
    Type: Application
    Filed: July 3, 2019
    Publication date: October 24, 2019
    Inventors: Jia-Ning Xiang, Xuesong Xu, Hao-Wei Shih, Wai-si Eng