Patents by Inventor HAOYU XIAO

HAOYU XIAO has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20240190968
    Abstract: The present disclosure discloses a B7H6 antibody and use thereof. The antibody includes heavy chain CDR1, heavy chain CDR2 and heavy chain CDR3; and light chain CDR1, light chain CDR2 and light chain CDR3. The antibody of the present disclosure is capable of binding to B7H6, and promoting the binding of B7H6 to the NK cell activating receptor NKp30, with an anti-cancer function.
    Type: Application
    Filed: February 22, 2024
    Publication date: June 13, 2024
    Applicant: HEFEI TG IMMUNOPHARMA CO., LTD.
    Inventors: Zhigang TIAN, Guoshuai CAO, Weihua XIAO, Rui SUN, Haoyu SUN
  • Publication number: 20240166752
    Abstract: Disclosed is an antibody and use thereof. The antibody or antigen binding fragment includes CDR sequences selected from at least one of heavy-chain variable region CDR sequences: SEQ ID NOs: 1-3; and light-chain variable region CDR sequences: SEQ ID NOs: 4-6. The antibody prepared by the present disclosure can effectively bind to the ?3 domain of MICA or MICB, and further, promote the binding of NKG2D to MICA and/or MICB, and can effectively treat or prevent related diseases mediated by MICA and/or MICB, such as promoting the killing of tumors by NK cell.
    Type: Application
    Filed: January 29, 2024
    Publication date: May 23, 2024
    Applicant: HEFEI TG IMMUNOPHARMA CO., LTD.
    Inventors: Zhigang TIAN, Guoshuai CAO, Weihua XIAO, Rui SUN, Haoyu SUN
  • Publication number: 20240124615
    Abstract: Provided are a bispecific antibody and use thereof. The recombinant antibody includes: a CDR Sequence selected from at least one of CD3 antibody variable region CDR sequences: SEQ ID NO: 1 to SEQ ID NO: 6, and B7H6 antibody variable region CDR sequences: SEQ ID NO: 7 to SEQ ID NO: 12; or an amino acid sequence having at least 95% identity thereto. The recombinant antibodies prepared according to the present application can simultaneously target CD3 and B7H6 antigens, and they have a. significantly prolonged half-life, exhibiting a stronger tumor-inhibiting ability than single-target antibodies.
    Type: Application
    Filed: December 20, 2023
    Publication date: April 18, 2024
    Inventors: Zhigang TIAN, Ying CHENG, Weihua XIAO, Guoshuai CAO, Haoyu SUN, Rui SUN
  • Publication number: 20240102782
    Abstract: The invention provides a method for evaluating deep-buried tunnel blasting parameters, and belongs to the technical field of mine engineering. The method comprises: setting multiple diverse blasting schemes; selecting a plurality of test sections with the same geological characteristics, the number of the test sections corresponding to the number of the blasting schemes; blasting the test sections using the blasting schemes, and obtaining diversified monitoring data of each test section; and comparing the diversified monitoring data to select the optimal blasting schemes for the test sections. According to the method for evaluating the deep-buried tunnel blasting parameters, by implementing different blasting schemes in test sections with the same geological characteristics, diversified monitoring data of the test sections are obtained and compared to select the optimal blasting schemes for the test sections, so as to ensure the safety and quality of blasting excavation of deep-buried tunnels.
    Type: Application
    Filed: September 5, 2023
    Publication date: March 28, 2024
    Inventors: Nuwen Xu, Biao Li, Quanfu Ding, Haoyu Mao, Peiwei Xiao, Xiang Zhou, Xinchao Ding, Yuepeng Sun, Yong Xia, Jun Liu, Zhiqiang Sun
  • Patent number: 9900355
    Abstract: According to an example, a first terminal device uploads sharing information to a server, the server sends identification information related to the sharing information to the first terminal device according to the sharing information, and the first terminal device transforms the identification information into a sound signal, and plays the sound signal. a second terminal device receives the sound signal, parses the sound signal to obtain the identification information, and sends a download request comprising the identifier information to the server. The server sends the sharing information to the second terminal device according to the download request.
    Type: Grant
    Filed: June 24, 2015
    Date of Patent: February 20, 2018
    Assignee: TENCENT TECHNOLOGY (SHENZHEN) COMPANY LIMITED
    Inventors: Zhihao Zheng, Jia Ma, Huixing Wang, Yuhong Tian, Huabin Xu, Xiaopeng Shen, Guanghai Wen, Qianbiao Xiang, Qiaoyu Xu, Shuzhan Yang, Jiawei Lv, Qing Mao, Yiting Zhou, Haoyu Xiao, Zhu Liang, Yong Zeng
  • Patent number: 9219808
    Abstract: A method for synchronizing between a first address book on a user terminal and a second address book on an SNS network includes determining a synchronization target and, when the synchronization target is determined as the first address book, downloading contact information from the second address book to the user terminal. The method also includes, when the synchronization target is determined as the second address book, uploading contact information from the first address book to the SNS network, and matching the contact information in the first address book against the contact information in the second address book. Further, the method includes identifying a contact person having same contact information based on the matching and synchronizing information of the contact person in the first address book and information of the contact person in the second address book.
    Type: Grant
    Filed: December 11, 2013
    Date of Patent: December 22, 2015
    Assignee: TENCENT TECHNOLOGY (SHENZHEN) COMPANY LIMITED
    Inventors: Shuangquan Yu, Guanghai Wen, Haoyu Xiao, Baohua Wang
  • Publication number: 20150295962
    Abstract: According to an example, a first terminal device uploads sharing information to a server, the server sends identification information related to the sharing information to the first terminal device according to the sharing information, and the first terminal device transforms the identification information into a sound signal, and plays the sound signal. a second terminal device receives the sound signal, parses the sound signal to obtain the identification information, and sends a download request comprising the identifier information to the server. The server sends the sharing information to the second terminal device according to the download request.
    Type: Application
    Filed: June 24, 2015
    Publication date: October 15, 2015
    Inventors: Zhihao ZHENG, Jia MA, Huixing WANG, Yuhong TIAN, Huabin XU, Xiaopeng SHEN, Guanghai WEN, Qianbiao XIANG, Qiaoyu XU, Shuzhan YANG, Jiawei LV, Qing MAO, Yiting ZHOU, Haoyu XIAO, Zhu LIANG, Yong ZENG
  • Publication number: 20140099930
    Abstract: A method for synchronizing between a first address book on a user terminal and a second address book on an SNS network includes determining a synchronization target and, when the synchronization target is determined as the first address book, downloading contact information from the second address book to the user terminal. The method also includes, when the synchronization target is determined as the second address book, uploading contact information from the first address book to the SNS network, and matching the contact information in the first address book against the contact information in the second address book. Further, the method includes identifying a contact person having same contact information based on the matching and synchronizing information of the contact person in the first address book and information of the contact person in the second address book.
    Type: Application
    Filed: December 11, 2013
    Publication date: April 10, 2014
    Applicant: TENCENT TECHNOLOGY (SHENZHEN) COMPANY LIMITED
    Inventors: SHUANGQUAN YU, GUANGHAI WEN, HAOYU XIAO, BAOHUA WANG