Abstract: Embodiments are described for treating a fluid, e.g., a biological fluid. The embodiments may include systems, apparatuses, and methods. Embodiments may provide for a flow cell, with a plurality of manipulation elements, through which a fluid is flowed. The fluid may be treated (e.g., exposed to energy) as it moves through the flow cell. In embodiments, the flow cell may be used to inactivate pathogens in the fluid.

Abstract: Embodiments are described for treating a fluid, e.g., a biological fluid. The embodiments may include systems, apparatuses, and methods. Embodiments may provide for a flow cell, with a plurality of manipulation elements, through which a fluid is flowed. The fluid may be treated (e.g., exposed to energy) as it moves through the flow cell. In embodiments, the flow cell may be used to inactivate pathogens in the fluid.

Abstract: Embodiments are described for treating a fluid, e.g., a biological fluid. The embodiments may include systems, apparatuses, and methods. Embodiments may provide for a flow cell, with a plurality of manipulation elements, through which a fluid is flowed. The fluid may be treated (e.g., exposed to energy) as it moves through the flow cell. In embodiments, the flow cell may be used to inactivate pathogens in the fluid.

Abstract: An articulating electrosurgical instrument includes a housing having an elongated shaft extending therefrom and a wrist assembly operably supported to a distal end of the elongated shaft and configured to support an end effector assembly at distal end thereof. The wrist assembly includes a proximal link operably coupled to the distal end of the elongated shaft, a distal link operably coupled to the end effector assembly, and a central link operably coupled between the proximal link and the distal link. A transition lumen is configured to be received within the distal link, central link and proximal link. The transition lumen includes a helical passageway defined therein configured to guide a blade rod therethrough for operable engagement with a blade disposed within the end effector assembly.

Abstract: An end effector assembly of a surgical instrument includes a clevis defining a longitudinal axis and including first and second arms spaced-apart relative to one another and first and second jaw members supported by the clevis. At least one of the jaw members is movable relative to the other and the clevis between a spaced-apart position and an approximated position for grasping tissue between the jaw members. The clevis includes first and second locating features on outwardly-facings sides of the first and second spaced-apart arms, respectively. The first and second locating features are configured to facilitate engagement and alignment of the end effector assembly within a test fixture.

Abstract: A jaw member of a surgical instrument includes a structural frame, an insulative spacer supported on the structural frame, an electrically conductive tissue contacting plate supported on the insulative spacer, and a lead wire. The spacer defines a pocket at an upper portion thereof and includes a channel extending from the pocket, through the spacer, to a bottom portion of the spacer. The channel defines a substantially U-shaped configuration having first and second radiused corners at the bottom portion of the spacer. The lead wire is attached to an underside of the plate at an attachment point within the pocket and extends distally from the attachment point into the channel, through the channel, over the first and second radiused corners, and proximally from the jaw member. The lead wire is adapted to connect to a source of energy to energize the plate for treating tissue.

Abstract: A surgical end effector assembly includes a clevis, first and second jaw members, and first and second lead wires. The clevis defines first and second arms spaced-apart relative to one another and extending from a proximal body and a finger extending from the proximal body at least partially between the arms. The finger defines a mouth at a free distal end thereof and a channel in communication with the mouth. The jaw members include proximal flange portions at least partially disposed between the arms, distal body portions extending distally from the clevis, and electrically conductive tissue contacting surfaces. At least one jaw member is movable to grasp tissue. The lead wires are connected to the tissue contacting surfaces and extend proximally from the distal body portions of the first and second jaw members through the mouth and into the channel of the finger of the clevis.

Abstract: A robotic system includes an electrosurgical instrument having an instrument housing with a shaft and first and second jaw members attached thereto movable to grasp tissue. An input is coupled to a jaw drive rod and is configured to move the jaw members. A strain gauge is coupled to the jaw drive rod and is configured to measure an amount of strain thereon and communicate the amount of strain to a robotic controller. A handle is remotely disposed relative to the instrument housing and is configured to communicate with the input for controlling the jaw members. The handle includes a housing having components therein and a lever operably associated therewith such that movement of the lever relative to the housing correlates to movement of the jaw members. The components are configured to operably regulate the resistance of the lever in response to the amount of strain from the strain gauge.

Abstract: A robotic system includes an electrosurgical instrument having an instrument housing having a shaft with an end effector assembly and first and second jaw members attached thereto movable to grasp tissue. An input is configured to move the jaw members and is configured to operably couple to a torque sensor that measures the torque of the input during rotation thereof. A handle is remotely disposed relative to the instrument housing and is configured to communicate with the input for controlling the movement of the jaw members. A housing having a lever operably coupled thereto, houses components therein configured to operably connect to the input such that movement of the lever correlates to movement of the jaw members. The components are configured to regulate the resistance of the lever in response to the feedback from the torque sensor.

Abstract: A robotic system includes an electrosurgical instrument having an instrument housing having a shaft with an end effector assembly and first and second jaw members attached thereto movable to grasp tissue. An input is operably coupled to the instrument housing and is configured to move the jaw members. A handle is remotely disposed relative to the instrument housing and is configured to communicate with the input for controlling the jaw members, the handle having a lever configured to cooperate with the input to control the jaw members relative to movement of the lever. The lever moves between a homing position and a first position correlating to the jaw members closing with a pressure therebetween in the range of about 0.1 kg/cm2 to about 2 kg/cm2. The lever further movable to a seal position correlating to the jaw members closing about tissue with a pressure between about 3 kg/cm2 to about 16 kg/cm2 for sealing.

Abstract: A robotic surgical instrument includes a housing and a shaft extending distally from the housing and including proximal and distal segments and an articulating portion interconnecting the segments. An end effector assembly is coupled to the distal segment and a plurality of actuation components extends through at least a portion of the shaft to enable selective actuation of the end effector assembly. A seal configuration is operably associated with a proximal body portion of a proximal link of the articulating portion of the shaft to establish seals against an interior annular surface of the shaft, about each actuation component of the plurality of actuation components, and within a distal end portion of the proximal segment of the shaft to inhibit fluid communication proximally into the proximal segment of the shaft.

Abstract: A robotic surgical instrument includes a housing, a support plate disposed within the housing, and a shaft having a proximal end portion coupled to the support plate within the housing, a proximal segment, a distal segment, and an articulating portion interconnecting the proximal and distal segments. An end effector assembly is coupled to the distal segment of the shaft. A plurality of actuation components extends through the support plate and at least a portion of the shaft to operably couple to at least one of the end effector assembly, the articulating portion, or the distal segment to enable selective actuation of the end effector assembly. A seal configuration establishes seals against an interior annular surface of the shaft, about each actuation component of the plurality of actuation components, and within the proximal end portion of the shaft to inhibit fluid communication from the shaft into the housing.

Abstract: Embodiments are described for treating a fluid, e.g., a biological fluid. The embodiments may include systems, apparatuses, and methods. Embodiments may provide for a flow cell, with a plurality of manipulation elements, through which a fluid is flowed. The fluid may be treated (e.g., exposed to energy) as it moves through the flow cell. In embodiments, the flow cell may be used to inactivate pathogens in the fluid.

Abstract: Embodiments are described for treating a fluid, e.g., a biological fluid. The embodiments may include systems, apparatuses, and methods. Embodiments may provide for a flow cell, with a plurality of manipulation elements, through which a fluid is flowed. The fluid may be treated (e.g., exposed to energy) as it moves through the flow cell. In embodiments, the flow cell may be used to inactivate pathogens in the fluid.