Patents by Inventor Harold B. Levene

Harold B. Levene has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 5732707
    Abstract: Myocardial perfusion is assessed quantitatively by an ultrasonic echocardiographic procedure in which: the myocardium is ultrasonically imaged; an ultrasonic contrast agent consisting of a suspension of pressure-stable, water-insoluble gas-containing microspheres sized to pass through the pulmonary capillaries is injected intravenously; imaging is continued through the first transit of the microspheres through the myocardium; the videodensity versus time relationship is determined from the images; and blood flow through the myocardium is calculated from that relationship.
    Type: Grant
    Filed: June 5, 1996
    Date of Patent: March 31, 1998
    Assignee: Molecular Biosystems, Inc.
    Inventors: Kenneth J. Widder, Harold B. Levene, Gary L. Bales
  • Patent number: 5179955
    Abstract: Abdominal ultrasound imaging is carried out by oral or rectal administration of an aqueous imaging agent containing micron size clay particles together with a sufficient amount of a solubilized hydrocolloid to maintain the particles in suspension. The walls of the stomach, duodenum and colon become coated with the clay particles and are thereby more clearly delineated by the ultrasonic imaging beam. At the same time, ultrasonic waves partially pass through the walls and delineate structures outside thereof. Wall delineation and wall transparency can thereby be simultaneously achieved.
    Type: Grant
    Filed: May 28, 1991
    Date of Patent: January 19, 1993
    Assignee: Molecular Biosystems, Inc.
    Inventors: Harold B. Levene, James L. Barnhart, Kenneth J. Widder
  • Patent number: 5107842
    Abstract: A method is provided for enhanced ultrasonic imaging of the gastrointestinal tract by employing an imaging agent comprising an aqueous particulate dispersion of edible substances, such as insoluble brans and mineral particles. Hydrocolloid particles can also be used, preferably in combination with insoluble non-swelling edible particles.
    Type: Grant
    Filed: February 22, 1991
    Date of Patent: April 28, 1992
    Assignee: Molecular Biosystems, Inc.
    Inventors: Harold B. Levene, Elaine Villapando, James L. Barnhart, Kenneth J. Widder