Patents by Inventor Harold Leon Newmark

Harold Leon Newmark has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 4082737
    Abstract: Thymosin fraction 5 has been widely employed recently in the clinical investigation of this thymic hormone. This material is a hormonally active proteinaceous composition which is involved in the regulation of cell-mediated immunity. The present disclosure provides a solid, stable, endotoxin and pyrogen free thymosin fraction 5 composition suitable for reconstitution for injection.
    Type: Grant
    Filed: February 22, 1977
    Date of Patent: April 4, 1978
    Assignee: Hoffmann-La Roche Inc.
    Inventors: Weldon Courtney McGregor, Harold Leon Newmark, Armin Hermann Ramel
  • Patent number: 4029805
    Abstract: Compounds represented by the formula ##STR1## wherein A is ##STR2## R is hydrogen, substituted or unsubstituted lower alkenyl or alkyl of 1 to 8 carbon atoms in the alkyl chain, phenyl or substituted phenyl, R.sub.1 is phenyl, substituted phenyl or lower alkyl substituted with phenyl, hydrates thereof, andPharmaceutically acceptable basic salts of said compounds or hydrates, useful as antibacterial therapeutic agents in the treatment of infectious diseases caused by Gram-positive and Gram-negative bacteria, particularly Gram-negative bacteria and particularly advantageous because of their stability in aqueous solution are disclosed.
    Type: Grant
    Filed: February 13, 1976
    Date of Patent: June 14, 1977
    Assignee: Hoffmann-La Roche Inc.
    Inventors: Alexander S. Emodi, Harold Leon Newmark, Leonard Joseph Scialpi
  • Patent number: 4022913
    Abstract: High potency compositions of vitamin A acetate and/or vitamin A alcohol stabilized against the formation of crystals by vitamin A palmitate are provided.
    Type: Grant
    Filed: July 3, 1975
    Date of Patent: May 10, 1977
    Assignee: Hoffmann-La Roche Inc.
    Inventor: Harold Leon Newmark
  • Patent number: 3989830
    Abstract: Stabilization of the copper II complex of 6-methoxy-1-phenazinol 5,10-dioxide, when used in a variety of dosage forms, is achieved by the addition of a 2-20% molar excess of copper ions to the specific dosage form.
    Type: Grant
    Filed: August 1, 1974
    Date of Patent: November 2, 1976
    Assignee: Hoffmann-La Roche Inc.
    Inventors: Martin Howard Infeld, Harold Leon Newmark
  • Patent number: 3969524
    Abstract: The preparation of relatively stable injectable solutions from dry powder formulations containing from 1.0 to 2.0 moles of anhydrous sodium carbonate per mole of amoxicillin free acid is disclosed. The solutions are suitable for administration by intravenous and intramuscular injection and intravenous drip.
    Type: Grant
    Filed: August 13, 1974
    Date of Patent: July 13, 1976
    Assignee: Hoffmann-La Roche Inc.
    Inventors: Alexander S. Emodi, Harold Leon Newmark, Leonard Joseph Scialpi
  • Patent number: 3958580
    Abstract: The amount of nitrogen dioxide in tobacco smoke is materially reduced by bringing the smoke into contact with uncombusted tobacco having dispersed therein an effective amount of a composition comprising a pharmaceutically acceptable salt of ascorbic acid or erthorbic acid or mixtures of such salts with their respective acids wherein the molar ratio of acid to salt does not exceed about 3:1.
    Type: Grant
    Filed: March 25, 1975
    Date of Patent: May 25, 1976
    Assignee: Hoffmann-La Roche Inc.
    Inventors: William Joseph Mergens, Harold Leon Newmark