Patents by Inventor Harold Schmitz
Harold Schmitz has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20110257119Abstract: This invention relates to compositions, and methods of use thereof, for improving microcirculation in a diabetic subject, and for dietary management of diabetes-associated condition(s) comprising administering certain polyphenols such as flavanols, procyanidins, or pharmaceutically acceptable salts or derivatives thereof to the subject in need thereof.Type: ApplicationFiled: June 27, 2011Publication date: October 20, 2011Inventors: Harold Schmitz, Catherine L. Kwik-Uribe, Hagen Schroeter
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Publication number: 20080090898Abstract: The invention relates to compositions, and methods of use thereof, for boosting immunity, e.g. innate immunity, in a subject in need thereof comprising administering to the subject certain polyphenols such as flavanols, procyanidins, or pharmaceutically acceptable salts or derivatives thereof.Type: ApplicationFiled: October 4, 2007Publication date: April 17, 2008Applicant: Mars, IncorporatedInventors: Harold Schmitz, Catherine Kwik-Uribe
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Publication number: 20080069794Abstract: The invention relates to compositions having an enhanced level of cocoa polyphenol and L-arginine which are effective in inducing vasodilation. The invention also relates to products including foods such as confectionary and pet foods, comprising cocoa polyphenols and L-arginine which are useful for inducing vasodilation.Type: ApplicationFiled: October 26, 2007Publication date: March 20, 2008Applicant: Mars, IncorporatedInventors: Leo Romanczyk, Harold Schmitz
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Publication number: 20080063690Abstract: The invention relates to products, including foods such as confectionary and pet foods, comprising nut skins. Exemplary nut skins are peanut and almond skins. The products may also contain cocoa polyphenol and/or L-arginine, and are useful for inducing vasodilation.Type: ApplicationFiled: October 31, 2007Publication date: March 13, 2008Applicant: Mars, IncorporatedInventors: Kati Chevaux, Harold Schmitz, Leo Romanczyk
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Publication number: 20070134400Abstract: Cocoa components having enhanced levels of cocoa polyphenols, processes for producing the cocoa components while conserving a significant amount of the cocoa polyphenols, compositions containing the cocoa components or the cocoa polyphenols, and methods of using the cocoa components or the cocoa polyphenols for improving the health of a mammal are described. The cocoa components include partially and fully defatted cocoa solids, cocoa nibs and fractions derived therefrom, cocoa polyphenol extracts, cocoa butter, chocolate liquors, and mixtures thereof. The invention provides processes for extracting fat from cocoa beans and for otherwise processing cocoa beans to yield a cocoa component having conserved concentrations of polyphenols relative to the starting materials.Type: ApplicationFiled: December 14, 2006Publication date: June 14, 2007Inventors: Kirk Kealey, Rodney Snyder, Leo Romanczyk, Hans Gever, Mary Myers, Eric Whitacre, John Hammerstone, Harold Schmitz
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Publication number: 20070042973Abstract: This invention relates to a method of treating, decreasing, or preventing pain or fever comprising administering to a subject in need thereof a composition comprising the inventive compounds.Type: ApplicationFiled: July 11, 2006Publication date: February 22, 2007Applicant: Mars, IncorporatedInventors: Leo Romanczyk, Harold Schmitz
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Publication number: 20070037872Abstract: The invention relates to compositions, and methods of use thereof, containing polyphenols such as flavanols, procyanidins, their derivatives and epimers thereof, for inducing peripheral blood vessel vasodilation, for example for treating or preventing peripheral vascular diseases.Type: ApplicationFiled: June 29, 2006Publication date: February 15, 2007Applicant: Mars, IncorporatedInventors: Catherine Kwik-Uribe, Harold Schmitz, Mark Kelm, John Hammerstone
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Publication number: 20070004652Abstract: The invention relates to compositions, such as pharmaceuticals, foods, food additives, or dietary supplements, containing a flavanol, an A-type procyanidins, a B-type procyanidin or a derivative thereof, and methods of use thereof, for treatment and/or prevention of occlusive thrombosis and related conditions.Type: ApplicationFiled: June 29, 2006Publication date: January 4, 2007Applicant: Mars, IncorporatedInventors: Harold Schmitz, Catherine Kwik-Uribe, Paul Jones
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Publication number: 20060293259Abstract: The invention relates to compositions containing derivatized flavanols such as methylated flavanols, and methods of use thereof for prophylactic or therapeutic treatment of a human or a veterinary animal for example as anti-platelet agents.Type: ApplicationFiled: June 28, 2006Publication date: December 28, 2006Applicant: Mars, IncorporatedInventors: Catherine Kwik-Uribe, Harold Schmitz, Mark Kelm, John Hammerstone
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Publication number: 20060281694Abstract: Disclosed are methods and compositions for improving blood glucose levels in a subject in need thereof.Type: ApplicationFiled: June 30, 2006Publication date: December 14, 2006Applicant: Mars, IncorporatedInventors: Leo Romanczyk, Harold Schmitz
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Publication number: 20060281693Abstract: This invention relates to a method of improving renal function comprising administering to a subject in need thereof a composition comprising the inventive compounds. Also disclosed is a method of improving renal function where the subject is at risk of or suffering from renal failure.Type: ApplicationFiled: June 28, 2006Publication date: December 14, 2006Applicant: Mars, IncorporatedInventors: Leo Romanczyk, Harold Schmitz
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Publication number: 20060276417Abstract: This invention relates to a method of treating inflammation comprising administering to a subject in need thereof a composition comprising the inventive compounds. Also disclosed is a method of treating inflammation where the subject is suffering from a rheumatic or inflammatory bowel disease.Type: ApplicationFiled: June 28, 2006Publication date: December 7, 2006Applicant: Mars, IncorporatedInventors: Leo Romanczyk, Harold Schmitz
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Publication number: 20050277600Abstract: The invention relates to compositions, such as pharmaceuticals, foods, food additives, or dietary supplements, containing dimer digallates, and methods of use thereof, for prophylactic or therapeutic treatment of a human or a veterinary animal to treat or prevent NO-responsive health conditions, treat hypertension, cardiovascular disease, coronary artery disease, diabetes, cognitive dysfunction or disorder and/or vascular circulation disorders, prevent or reduce the risk of heart attack, stroke, congestive heart failure and/or kidney failure, or to improve blood flow, for example renal blood flow. The composition may optionally contain an additional NO modulating agent and/or a vascular-protective or therapeutic agent, or may be administered in combination with such an agent.Type: ApplicationFiled: June 14, 2005Publication date: December 15, 2005Applicant: Mars, IncroporatedInventors: Harold Schmitz, Catherine Kwik-Uribe, Mark Kelm, John Hammerstone, Leo Romanczyk
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Publication number: 20050267052Abstract: Disclosed and claimed are flavanols, e.g. epicatechin, compositions such as pharmaceutical compositions containing an effective amount of flavanols, e.g. epicatechin, and methods of treatment or prevention of hypertension using the same.Type: ApplicationFiled: June 24, 2005Publication date: December 1, 2005Applicant: Mars, IncorporatedInventors: Leo Romanczyk, Harold Schmitz
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Publication number: 20050245601Abstract: This invention relates to compositions containing polyphenols such as flavanols and their related oligomers, and methods for treating conditions associated with ErbB2 kinase overexpression, for example, treatment of cancers involving ErbB2 kinase overexpression.Type: ApplicationFiled: October 8, 2004Publication date: November 3, 2005Applicant: Mars, IncorporatedInventor: Harold Schmitz
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Publication number: 20050209171Abstract: Disclosed and claimed are cocoa extracts, compounds, combinations thereof and compositions containing the same, such as polyphenols or procyanidins, methods for preparing such extracts, compounds and compositions, as well as uses for them, especially a polymeric compound of the formula An, wherein A is a monomer of the formula: wherein n is an integer from 2 to 18, such that there is at least one terminal monomeric unit A, and one or a plurality of additional monomeric units; R is 3-(?)-OH, 3-(?)-OH, 3-(?)-O-sugar, or 3-(?)-O-sugar; bonding between adjacent monomers takes place at positions 4, 6 or 8; a bond of an additional monomeric unit in position 4 has alpha or beta stereochemistry; X, Y and Z are selected from the group consisting of monomeric unit A, hydrogen, and a sugar, with the provisos that as to the at least one terminal monomeric unit, bonding of the additional monomeric unit thereto (the bonding of the additional monomeric unit adjacent to the terminal monomeric unit) is at position 4 and opType: ApplicationFiled: December 3, 2004Publication date: September 22, 2005Applicant: Mars, IncorporatedInventors: Leo Romanczyk, Harold Schmitz
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Publication number: 20050164956Abstract: The invention relates to compositions, such as pharmaceuticals, foods, food additives, or dietary supplements, containing A-type procyanidins, and methods of use thereof, for prophylactic or therapeutic treatment of a human or a veterinary animal to treat or prevent NO-responsive health conditions, treat hypertension, cardiovascular disease, coronary artery disease and/or vascular circulation disorders, prevent or reduce the risk of heart attack, stroke, congestive heart failure and/or kidney failure, or to improve blood flow, for example renal blood flow. The composition may optionally contain an additional NO modulating agent and/or a cardiovascular-protective or therapeutic agent, or may be administered in combination with such an agent.Type: ApplicationFiled: January 28, 2005Publication date: July 28, 2005Applicant: Mars, IncorporatedInventors: Harold Schmitz, Catherine Kwik-Uribe, Mark Kelm, John Hammerstone
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Publication number: 20050089592Abstract: The invention relates to products, including foods such as confectionary and pet foods, comprising nut skins or polyphenol-containing nut skin extracts. Exemplary nut skins are peanut and almond skins. The products may also contain cocoa polyphenol and/or L-arginine, and are useful for inducing vasodilation.Type: ApplicationFiled: November 18, 2004Publication date: April 28, 2005Applicant: Mars, IncorporatedInventors: Kati Chevaux, Harold Schmitz, Leo Romanczyk
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Publication number: 20050085431Abstract: Polyphenol-containing compositions, for example procyanidins and derivatives thereof, and their use for treating hypertension are disclosed. Compositions may be used for human and veterinary use, and may be, for example, in a form of a food, a dietary supplement or a pharmaceutical.Type: ApplicationFiled: March 8, 2004Publication date: April 21, 2005Applicant: Mars, IncorporatedInventors: Leo Romanczyk, Harold Schmitz