Patents by Inventor Harrison Sikanyika

Harrison Sikanyika has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Substituted 1,2,4-triazines as tubulin inhibitors
    Patent number: 9732046
    Abstract: Compounds of general formula (I), (II), (III) and (V) are described for use in modulating microtubule polymerization and in the treatment of associated disease states. Use of compounds (I), (III) and (V) in the treatment of kinase-associated disease states is also described. Further described are novel compounds of formula (II), (III) and (V).
    Type: Grant
    Filed: July 28, 2015
    Date of Patent: August 15, 2017
    Assignee: YM BIOSCIENCES AUSTRALIA PTY LTD.
    Inventors: Christopher John Burns, Andrew Frederick Wilks, Michael Francis Harte, Harrison Sikanyika, Emmanuelle Fantino
  • TUBULIN INHIBITORS
    Publication number: 20160031835
    Abstract: Compounds of general formula (I), (II), (III) and (V) are described for use in modulating microtubule polymerisation and in the treatment of associated disease states. Use of compounds (I), (III) and (V) in the treatment of kinase-associated disease states is also described. Further described are novel compounds of formula (II), (III) and (V).
    Type: Application
    Filed: July 28, 2015
    Publication date: February 4, 2016
    Inventors: Christopher John Burns, Andrew Frederick Wilks, Michael Francis Harte, Harrison Sikanyika, Emmanuelle Fantino
  • Substituted pyrazines as tubulin inhibitors
    Patent number: 9139560
    Abstract: Compounds of general formula (I), (II), (III) and (V) are described for use in modulating microtubule polymerization and in the treatment of associated disease states. Use of compounds (I), (III) and (V) in the treatment of kinase-associated disease states is also described. Further described are novel compounds of formula (II), (III) and (V).
    Type: Grant
    Filed: February 28, 2014
    Date of Patent: September 22, 2015
    Assignee: YM Biosciences Australia Pty Ltd.
    Inventors: Christopher John Burns, Andrew Frederick Wilks, Michael Francis Harte, Harrison Sikanyika, Emmanuelle Fantino
  • TUBULIN INHIBITORS
    Publication number: 20140221396
    Abstract: Compounds of general formula (I), (II), (III) and (V) are described for use in modulating microtubule polymerisation and in the treatment of associated disease states. Use of compounds (I), (III) and (V) in the treatment of kinase-associated disease states is also described. Further described are novel compounds of formula (II), (III) and (V).
    Type: Application
    Filed: February 28, 2014
    Publication date: August 7, 2014
    Applicant: YM Biosciences Australia Pty Ltd.
    Inventors: Christopher John BURNS, Andrew Frederick WILKS, Michael Francis HARTE, Harrison SIKANYIKA, Emmanuelle FANTINO
  • TUBULIN INHIBITORS
    Publication number: 20130274263
    Abstract: Compounds of general formula (I), (II), (III) and (V) are described for use in modulating microtubule polymerisation and in the treatment of associated disease states. Use of compounds (I), (III) and (V) in the treatment of kinase-associated disease states is also described. Further described are novel compounds of formula (II), (III) and (V).
    Type: Application
    Filed: March 12, 2013
    Publication date: October 17, 2013
    Inventors: Christopher John Burns, Andrew Frederick Wilks, Michael Francis Harte, Harrison Sikanyika, Emmanuelle Fantino
  • 2-phenyl pyrazines as tubulin inhibitors
    Patent number: 8394806
    Abstract: Compounds of general formula (I), (II), (III) and (V) are described for use in modulating microtubule polymerisation and in the treatment of associated disease states. Use of compounds (I), (III) and (V) in the treatment of kinase-associated disease states is also described. Further described are novel compounds of formula (II), (III) and (V).
    Type: Grant
    Filed: July 14, 2011
    Date of Patent: March 12, 2013
    Assignee: YM Biosciences Australia Pty Ltd
    Inventors: Christopher John Burns, Andrew Frederick Wilks, Michael Francis Harte, Harrison Sikanyika, Emmanuelle Fantino
  • Pyrazine-based tubulin inhibitors
    Patent number: 8084456
    Abstract: A compound of general formula (I) or pharmaceutically acceptable prodrugs, salts, hydrates, solvates, crystal forms or diastereomers thereof is described. A method of treating a hyperproliferation-related disease state or disorder in a subject using a compound of formula (I) is also described.
    Type: Grant
    Filed: December 11, 2003
    Date of Patent: December 27, 2011
    Assignee: YM Biosciences Australia Pty Ltd
    Inventors: Christopher John Burns, Andrew Frederick Wilks, Xianyong Bu, Harrison Sikanyika, Michael Francis Harte
  • TUBULIN INHIBITORS
    Publication number: 20110269760
    Abstract: Compounds of general formula (I), (II), (III) and (V) are described for use in modulating microtubule polymerisation and in the treatment of associated disease states. Use of compounds (I), (III) and (V) in the treatment of kinase-associated disease states is also described. Further described are novel compounds of formula (II), (III) and (V).
    Type: Application
    Filed: July 14, 2011
    Publication date: November 3, 2011
    Applicant: Cytopia Research Pty Ltd
    Inventors: Christopher John Burns, Andrew Frederick Wilks, Michael Francis Harte, Harrison Sikanyika, Emmanuelle Fantino
  • 2-phenyl pyrimidines which are tubulin inhibitors
    Patent number: 7981900
    Abstract: Compounds of general formula (I), (II) (III) and (V) are described for use in modulating microtubule polymerisation and in the treatment of associated disease states. Use of compounds (I), (III) and (V) in the treatment of kinase-associated disease states is also described. Further described are novel compounds of formula (II), (III) and (V).
    Type: Grant
    Filed: December 3, 2004
    Date of Patent: July 19, 2011
    Assignee: YM Biosciences Australia Pty Ltd
    Inventors: Christopher John Burns, Andrew Frederick Wilks, Michael Francis Harte, Harrison Sikanyika, Emmanuelle Fantino
  • Tubulin Inhibitors
    Publication number: 20080194583
    Abstract: Compounds of general formula (I), (II) (III) and (V) are described for use in modulating microtubule polymerisation and in the treatment of associated disease states. Use of compounds (I), (III) and (V) in the treatment of kinase-associated disease states is also described. Further described are novel compounds of formula (II), (III) and (V).
    Type: Application
    Filed: December 3, 2004
    Publication date: August 14, 2008
    Inventors: Christopher John Burns, Andrew Frederick Wilks, Michael Francis Harte, Harrison Sikanyika, Emmanuelle Fantino, Collette Gloria Kewdale
  • Pyrazine-based tubulin inhibitors
    Publication number: 20070082894
    Abstract: A compound of general formula (I) or pharmaceutically acceptable prodrugs, salts, hydrates, solvates, crystal forms or diastereomers thereof is described. A method of treating a hyperproliferation-related disease state or disorder in a subject using a compound of formula (I) is also described.
    Type: Application
    Filed: December 11, 2003
    Publication date: April 12, 2007
    Applicant: Cytopia Pty Ltd
    Inventors: Christopher Burns, Andrew Wilks, Xianyong Bu, Harrison Sikanyika, Michael Harte