Patents by Inventor Harry D. Danforth

Harry D. Danforth has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Production of an immunovariant strain of contributes to strain cross-protection with other
    Patent number: 6969602
    Abstract: An immunovariant strain of Eimeria maxima was isolated. Vaccines incorporating the immunovariant strain are effective in eliciting immunological protection against coccidial infection.
    Type: Grant
    Filed: April 20, 2001
    Date of Patent: November 29, 2005
    Assignees: The United States of America as represented by the Secretary of the Agriculture, University of Guelph
    Inventors: Harry D. Danforth, M. Aggie Fernando, John R. Barta
  • Use of echinacea as a feed additive to enhance protection against coccidiosis
    Patent number: 6767546
    Abstract: Echinacea dietary supplements are useful adjuvants for live anticoccidial vaccines. Feed supplementation with Echinacea preparations enhances the immune response to such vaccines. Echinacea purpurea in amounts of about 0.1% to 0.5% administered for about two weeks to day-old chicks has been found effective for providing significant weight gain compared to vaccination alone.
    Type: Grant
    Filed: August 17, 2001
    Date of Patent: July 27, 2004
    Assignees: The United States of America as represented by the Secretary of Agriculture, Triarco Industries, Inc.
    Inventors: Patricia C. Allen, Mark Anderson, Harry D. Danforth
  • Isolated protein from Eimeria useful as a cross species vaccine
    Patent number: 5709862
    Abstract: A cloned gene or fragment thereof encodes antigenic proteins that bind with a monoclonal or polyvalent antibody that is directed against an antigenic protein of avian coccidia.
    Type: Grant
    Filed: November 8, 1993
    Date of Patent: January 20, 1998
    Assignees: British Technology Group USA Inc., The United States of America as represented by the Department of Agriculture
    Inventors: David M. Anderson, Russell J. McCandliss, Susan Lee Strausberg, Robert L. Strausberg, Michael D. Ruff, Harry D. Danforth, Patricia C. Augustine
  • Eimeria antigenic composition which elicits antibodies against avian coccidiosis
    Patent number: 5656485
    Abstract: This invention relates to novel recombinant antigenic proteins of avian coccidiosis, and fragments thereof containing antigenic determinants, and to the genes that encode the antigenic peptides. This invention also relates to vaccines made using the novel antigenic proteins of avian coccidiosis and to methods of immunizing chickens against avian coccidia.
    Type: Grant
    Filed: August 2, 1996
    Date of Patent: August 12, 1997
    Assignee: BTG USA Inc.
    Inventors: James W. Jacobson, Robert L. Strausberg, Susan D. Wilson, Sharon H. Pope, Susan Lee Strausberg, Michael D. Ruff, Patricia C. Augustine, Harry D. Danforth
  • Eimeria antigenic composition which elicits antibodies against avian coccidiosis
    Patent number: 5597571
    Abstract: This invention relates to novel recombinant antigenic proteins of avian coccidiosis, and fragments thereof containing antigenic determinants, and to the genes that encode the antigenic peptides. This invention also relates to vaccines made using the novel antigenic proteins of avian coccidiosis and to methods of immunizing chickens against avian coccidia.
    Type: Grant
    Filed: June 7, 1995
    Date of Patent: January 28, 1997
    Assignee: British Technology Group USA Inc.
    Inventors: James W. Jacobson, Robert L. Strausberg, Susan D. Wilson, Sharon H. Pope, Susan L. Strausberg, Michael D. Ruff, Patricia C. Augustine, Harry D. Danforth
  • Eimeria antigenic composition which elicits antibodies against avian coccidiosis
    Patent number: 5482709
    Abstract: This invention relates to novel recombinant antigenic proteins of avian coccidiosis, and fragments thereof containing antigenic determinants, and to the genes that encode the antigenic peptides. This invention also relates to vaccines made using the novel antigenic proteins of avian coccidiosis and to methods of immunizing chickens against avian coccidia.
    Type: Grant
    Filed: November 8, 1993
    Date of Patent: January 9, 1996
    Assignees: British Technology Group USA Inc., The United States of America as represented by the Dept. of Agriculture
    Inventors: James W. Jacobson, Robert L. Strausberg, Susan D. Wilson, Sharon H. Pope, Susan L. Strausberg, Michael D. Ruff, Patricia C. Augustine, Harry D. Danforth
  • 25 KD coccidial antigen of eimeria tenella
    Patent number: 5279960
    Abstract: A cloned gene or fragment thereof encodes antigenic proteins that bind with a monoclonal or polyvalent antibody that is directed against an antigenic protein of avian coccidia.
    Type: Grant
    Filed: May 5, 1992
    Date of Patent: January 18, 1994
    Assignees: Enzon Corp., U.S.A. Dept. of Agriculture
    Inventors: David M. Anderson, Russell J. McCandliss, Susan L. Strausberg, Robert L. Strausberg, Michael D. Ruff, Harry D. Danforth, Patricia C. Augustine
  • Genetically engineered coccidiosis sporozoite 21.5 Kb antigen, ac-6b
    Patent number: 5273901
    Abstract: This invention relates to novel recombinant antigenic proteins of avian coccidiosis, and fragments thereof containing antigenic determinants, and to the genes that encode the antigenic peptides. This invention also relates to vaccines made using the novel antigenic proteins of avian coccidiosis and to methods of immunizing chickens against avian coccidia.
    Type: Grant
    Filed: September 12, 1990
    Date of Patent: December 28, 1993
    Assignees: Enzon Corp., U.S. Dept. of Agriculture
    Inventors: James W. Jacobson, Robert L. Strausberg, Susan D. Wilson, Sharon H. Pope, Susan L. Strausberg, Michael D. Ruff, Patricia C. Augustine, Harry D. Danforth
  • Cloned genes coding for avian coccidiosis antigens which induce a cell-mediated immune response
    Patent number: 5122471
    Abstract: Disclosed are DnA sequences which code for antigenic proteins, methods for identifying such DNA sequences, and antigens coded for by such DNA sequences.The first step of the method is to provide a multiplicity of DNA sequences. These sequences are then inserted into DNA expression vectors to form recombinant expression vectors. The expression vectors are inserted into suitable hosts to form transformants which express the DNA sequences. The transformants are then contacted with antibodies directed against Eimeria antigens to identify transformants containing DNA sequences which code for Eimeria antigens. These antigens are then produced from the DNA sequences identified as coding for the antigens. The antigens so produced are contacted with white blood cells which effect a cell-mediated immune response, which white blood cells are sensitized to an antigenic Eimeria protein, to thereby identify DNA sequences which code for antigens that induce a cell-mediated immune response to avian coccidiosis.
    Type: Grant
    Filed: February 9, 1989
    Date of Patent: June 16, 1992
    Assignee: The United States of America as represented by the Secretary of Agriculture
    Inventors: Mark C. Jenkins, Hyun S. Lillehoj, John B. Dame, Harry D. Danforth, Michael D. Ruff