Patents by Inventor Haruhiko KAMADA

Haruhiko KAMADA has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • OPTIC NERVE PROTECTING AGENT CONTAINING ANTI-LRP1 ANTIBODY
    Publication number: 20240034787
    Abstract: The present invention relates to an optic nerve protecting agent containing an anti-low density lipoprotein receptor-related protein 1 (LRP1) antibody or an anti-LRP1 antibody fragment.
    Type: Application
    Filed: November 26, 2021
    Publication date: February 1, 2024
    Applicants: TOKYO UNIVERSITY OF PHARMACY & LIFE SCIENCES, NATIONAL INSTITUTES OF BIOMEDICAL INNOVATION, HEALTH AND NUTRITION
    Inventors: Hideki Hayashi, Norio Takagi, Yamato Kikkawa, Haruhiko Kamada, Satoshi Nagata
  • PD-1 Agonist-Containing Pharmaceutical Composition for Treating or PReventing TH2-Mediated Disease
    Publication number: 20230183347
    Abstract: A novel use of agonist to PD-1 is developed. Provided is a pharmaceutical composition for treating or preventing Th2-mediated diseases, the composition comprising an effective amount of a PD-1 agonist.
    Type: Application
    Filed: May 24, 2021
    Publication date: June 15, 2023
    Applicants: Foundation for Biomedical Research and Innovation at Kobe, National Institutes of Biomedical Innovation, Health and Nutrition, Meiji Seika Pharma Co., Ltd.
    Inventors: Tasuku Honjo, Akio Ohta, Masaki Tajima, Haruhiko Kamada, Satoshi Nagata, Kensuke Suzuki, Yuya Oshiro, Yosuke Tokumaru
  • Method for identifying drug-discovery target protein for development of antibody drug, and method for producing antibody against target protein
    Patent number: 11442066
    Abstract: Finding a protein of a minute amount present on a cell membrane to provide a method for producing an antibody against the protein. Producing an antibody using a protein identified by an identification method including: a labeling step of using a labeling agent comprising at least one selected from bis-iminobiotin compounds and bis-biotin compounds to obtain cells having a labeled protein; a degradation step of preparing a degradation product for an immobilization treatment, the degradation product containing the labeled protein; an immobilization step of immobilizing the labeled protein contained in the degradation product for an immobilization treatment on a stationary phase via a streptavidin mutant; a cleavage step of releasing an analysis sample from the stationary phase on which the labeled protein is immobilized; and an analysis step of analyzing the analysis sample to identify the labeled protein.
    Type: Grant
    Filed: February 19, 2018
    Date of Patent: September 13, 2022
    Assignees: MITSUI CHEMICALS, INC, NATIONAL INSTITUTES OF BIOMEDICAL INNOVATION HEALTH AND NUTRITION, SAVID THERAPEUTICS INC.
    Inventors: Tsuneji Suzuki, Yoshiyuki Totani, Kosuke Mano, Shinichi Banba, Haruhiko Kamada, Taisuke Nakayama, Hiroki Akiba, Kouhei Tsumoto, Tsuyoshi Inoue
  • METHOD FOR IDENTIFYING DRUG-DISCOVERY TARGET PROTEIN FOR DEVELOPMENT OF ANTIBODY DRUG, AND METHOD FOR PRODUCING ANTIBODY AGAINST TARGET PROTEIN
    Publication number: 20190383821
    Abstract: Finding a protein of a minute amount present on a cell membrane to provide a method for producing an antibody against the protein. Producing an antibody using a protein identified by an identification method including: a labeling step of using a labeling agent comprising at least one selected from bis-iminobiotin compounds and bis-biotin compounds to obtain cells having a labeled protein; a degradation step of preparing a degradation product for an immobilization treatment, the degradation product containing the labeled protein; an immobilization step of immobilizing the labeled protein contained in the degradation product for an immobilization treatment on a stationary phase via a streptavidin mutant; a cleavage step of releasing an analysis sample from the stationary phase on which the labeled protein is immobilized; and an analysis step of analyzing the analysis sample to identify the labeled protein.
    Type: Application
    Filed: February 19, 2018
    Publication date: December 19, 2019
    Applicants: MITSUI CHEMICALS, INC., NATIONAL INSTITUTES OF BIOMEDICAL INNOVATION, HEALTH AND NUTRITION, SAVID THERAPEUTICS INC.
    Inventors: Tsuneji SUZUKI, Yoshiyuki TOTANI, Kosuke MANO, Shinichi BANBA, Haruhiko KAMADA, Taisuke NAKAYAMA, Hiroki AKIBA, Kouhei TSUMOTO, Tsuyoshi INOUE