Patents by Inventor Haruki Eguchi

Haruki Eguchi has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 9434880
    Abstract: A new radical inhibitor, a composition containing the new radical inhibitor, and a radical generation inhibition method using the new radical inhibitor are provided. A radical inhibitor according to the present invention contains a salen complex compound of a bivalent metal.
    Type: Grant
    Filed: September 27, 2012
    Date of Patent: September 6, 2016
    Assignees: IHI CORPORATION
    Inventors: Yoshihiro Ishikawa, Haruki Eguchi
  • Publication number: 20160193337
    Abstract: The present invention provides a drug delivery system that overcomes conventional technical problems and that is readily put to practical use. Iron-salen complexes represented by General Formula (I) below. The invention renders iron-salen complexes magnetic, which can thus be used as drugs that can be delivered to affected areas in the body using the inherent magnetic properties of the drug without employing carriers composed of magnetic substances as has been done hitherto.
    Type: Application
    Filed: January 8, 2016
    Publication date: July 7, 2016
    Inventors: Haruki Eguchi, Yoshihiro Ishikawa
  • Patent number: 9314602
    Abstract: A magnetic body may be suitably applied to a drug delivery system using magnetism. Furthermore, a drug delivery control device allows the magnetic body to be suitably applied to drug delivery. The magnetic body includes a magnet and a cover part attached to an edge of the magnet. The cover part is composed of a material with high magnetic permeability, and a ratio of a length to a radius of the cover part is 10:1 to 7:3. The drug delivery control device includes the magnetic body, a head for supporting the magnetic body and a drive mechanism of the head that causes the head to operate along a projected region formed by the affected area with respect to a surface of a tissue. A magnetic field is applied from the magnetic body to the affected area where a magnetic drug is administered.
    Type: Grant
    Filed: December 24, 2010
    Date of Patent: April 19, 2016
    Assignees: IHI Corporation
    Inventors: Yoshihiro Ishikawa, Haruki Eguchi, Masakazu Hara
  • Patent number: 9282923
    Abstract: It is an object of the present invention to extend the usefulness of an iron-salen complex. The present invention is a new fluorochrome material containing Chemical Formula (I) below. However, M is Fe, Cr, Mn, Co, Ni, Mo, Ru, Rh, Pd, W, Re, Os, Ir, Pt, Nd, Sm, Eu, or Gd.
    Type: Grant
    Filed: May 12, 2011
    Date of Patent: March 15, 2016
    Assignees: IHI CORPORATION, Yoshihiro Ishikawa
    Inventors: Yoshihiro Ishikawa, Haruki Eguchi
  • Publication number: 20150351684
    Abstract: [Object] A system capable of designing an optimum administration form of a magnetic drug is provided. [Solution] The system: determines first information about an side-effect-related organ on which a magnetic drug produces a side effect, based on equipment analysis information after administering the magnetic drug (S208); further determines second information about a drug-efficacy-related organ in which drug efficacy of the magnetic drug should be demonstrated (S210); evaluates the administration form of the magnetic drug based on the first information and the second information; corrects the administration form of the magnetic drug based on an evaluation result (S224); and outputs information of the corrected administration form (S226).
    Type: Application
    Filed: December 25, 2013
    Publication date: December 10, 2015
    Inventors: Yoshihiro ISHIKAWA, Haruki EGUCHI
  • Patent number: 9208952
    Abstract: A material for constituting an electric double layer capacity that is stable at high temperatures and can expect a high electric capacity is provided. Such a material is an electric double layer capacitor material which is used as a material for constituting solid electrolytes 13 and 17 for an electric double layer capacitor 1 and is composed of a metal-salen complex compound.
    Type: Grant
    Filed: April 20, 2012
    Date of Patent: December 8, 2015
    Assignee: IHI Corporation
    Inventor: Haruki Eguchi
  • Publication number: 20150336998
    Abstract: The present disclosure relates to a ferromagnetic substance containing a crystal of a metal complex molecule in which a heterocycle is bonded to metal, the metal of the metal complex molecule is bonded to the metal of another metal complex via oxygen as a electron donor, and the ferromagnetic substance has a ferromagnetic property balanced with stability of crystals based on a metal—electron donor—metal bond angle that is from 130° to 160°. The present disclosure also relates to a drug containing, as a principal component, the crystal of the metal complex molecule.
    Type: Application
    Filed: August 5, 2015
    Publication date: November 26, 2015
    Applicants: IHI CORPORATION
    Inventors: Yoshihiro ISHIKAWA, Haruki EGUCHI
  • Publication number: 20150318095
    Abstract: [Object] A magnetization technique that enhances magnetic properties of an organic compound is provided without damaging properties of the organic compound or while maintaining the structure of the organic compound. [Solution] The present disclosure is a method for manufacturing a magnetic substance composed of crystals of a magnetization target compound and an electron acceptor by combining the magnetization target compound with the electron acceptor; forming a solution by dissolving a mixture of the magnetization target compound and the electron acceptor in a solvent; maintaining the solution in a very low temperature state and allowing the solution to deposit the crystals of the magnetic target compound and the electron acceptor; and separating the crystals from the solvent.
    Type: Application
    Filed: June 15, 2015
    Publication date: November 5, 2015
    Inventors: Yoshihiro ISHIKAWA, Haruki EGUCHI
  • Patent number: 9005757
    Abstract: The present invention provides a metal-salen complex compound having a controlled grain size that enables the metal-salen complex compound to exert its pharmacological effects as a medicine, at a target region. This metal-salen complex compound is composed of the following that has a crystal grain size of 8 ?m or less, and that is represented by the chemical formula below. N,N?-Bis(salicylidene)ethylenediamine metal M is Fe, Cr, Mn, Co, Ni, Mo, Ru, Rh, Pd, W, Re, Os, Ir, Pt, Nd, Sm, Eu, or Gd.
    Type: Grant
    Filed: December 21, 2011
    Date of Patent: April 14, 2015
    Assignees: IHI Corporation
    Inventors: Yoshihiro Ishikawa, Haruki Eguchi
  • Publication number: 20150028250
    Abstract: A magnetic composition containing a metal-salen complex compound which can be securely guided by a magnetic field to a target area to be preferably treated, and a method for producing the magnetic composition are provided. The magnetic composition is prepared by dispersing magnetic particles, which are obtained by coating a metal-salen complex compound with a dispersant, in a polar solvent by means of the dispersant. Furthermore, the magnetic composition production method includes a first step of mixing the metal-salen complex compound with the dispersant in an organic solvent and coating the metal-salen complex compound with the dispersant and a second step of dispersing the metal-salen complex in a polar solvent.
    Type: Application
    Filed: September 6, 2012
    Publication date: January 29, 2015
    Applicants: IHI Corporation
    Inventors: Yoshihiro Ishikawa, Haruki Eguchi
  • Patent number: 8933118
    Abstract: A drug containing a metal-salen complex compound which is effective for a brain tumor is provided. The present invention is an anti-brain-tumor drug containing a metal-salen complex compound represented by the following Chemical Formula (I). In the formula, M represents a metal atom which is Fe, Cr, Mn, Co, Ni, Mo, Ru, Rh, Pd, W, Re, Os, Ir, Pt, Nd, Sm, Eu, or Gd, and X represents a halogen atom.
    Type: Grant
    Filed: April 11, 2011
    Date of Patent: January 13, 2015
    Assignee: IHI Corporation
    Inventors: Yoshihiro Ishikawa, Haruki Eguchi
  • Publication number: 20140323566
    Abstract: A new self-magnetic metal-salen complex compound and its derivatives are provided. The present invention is a metal-salen complex compound including any one of the following compounds.
    Type: Application
    Filed: May 14, 2012
    Publication date: October 30, 2014
    Applicants: IHI Corporation
    Inventors: Yoshihiro Ishikawa, Haruki Eguchi
  • Publication number: 20140302604
    Abstract: A new radical inhibitor, a composition containing the new radical inhibitor, and a radical generation inhibition method using the new radical inhibitor are provided. A radical inhibitor according to the present invention contains a salen complex compound of a bivalent metal.
    Type: Application
    Filed: September 27, 2012
    Publication date: October 9, 2014
    Inventors: Yoshihiro Ishikawa, Haruki Eguchi
  • Publication number: 20140235883
    Abstract: A material for constituting an electric double layer capacity that is stable at high temperatures and can expect a high electric capacity is provided. Such a material is an electric double layer capacitor material which is used as a material for constituting solid electrolytes 13 and 17 for an electric double layer capacitor 1 and is composed of a metal-salen complex compound.
    Type: Application
    Filed: April 20, 2012
    Publication date: August 21, 2014
    Applicant: IHI CORPORATION
    Inventor: Haruki Eguchi
  • Publication number: 20140235684
    Abstract: A metal-salen complex compound responsive drug, which has an antidotal property capable of neutralizing cytotoxicity of a metal-salen complex compound, and an intra-corporeal behavior control system for the metal-salen complex compound are provided. This metal-salen complex compound responsive drug contains an effective amount of a metal chelating agent to suppress side effects by the metal-salen complex compound.
    Type: Application
    Filed: September 19, 2012
    Publication date: August 21, 2014
    Inventors: Yoshihiro Ishikawa, Haruki Eguchi
  • Publication number: 20140214380
    Abstract: It is intended to provide a drug delivery system which makes it possible to solve the existing technical problems and is easily usable in practice. A drug, which comprises an organic compound or an inorganic compound and has been magnetized by modifying a side chain and/or crosslinking side chains, is induced by a magnetic force into target tissues or an affected part.
    Type: Application
    Filed: March 13, 2014
    Publication date: July 31, 2014
    Inventors: Haruki EGUCHI, Yoshihiro Ishikawa
  • Publication number: 20140206635
    Abstract: A metal-salen complex compound, which exhibits excellent noninvasiveness and can be efficiently transferred to an affected site, a local anesthetic containing this metal-salen complex compound, and an antineoplastic drug containing this metal-salen complex compound are provided. Regarding the metal-salen complex compound, a metal atom part in each of two molecules of a metal-salen complex or a derivative of the metal-salen complex is dimerized via water, and the metal-salen complex compound is mixed with a base to produce an ointment.
    Type: Application
    Filed: May 10, 2012
    Publication date: July 24, 2014
    Applicants: IHI CORPORATION
    Inventors: Yoshihiro Ishikawa, Haruki Eguchi
  • Publication number: 20140112876
    Abstract: There are provided: an ultraviolet light absorber that has a sufficient UV-A and UV-B shielding effect, can be colored naturally to suit the color of the skin when applied to the skin, and can be favorably applied even to races with dark skin colors; and a cosmetic material using such an ultraviolet light absorber. The ultraviolet light absorber is one produced by substituting, at 10% or less, at least one element selected from the group consisting of Sc, Ti, V, Cr, Mn, Fe, Co, Ni, Cu, Zn, Ga, Ge, As, Y, Zr, Nb, Mo, Tc, Ru, Rh, Pd, Ag, Cd, Sn, Sb, Hf, W, Re, Os, Ir, Pt, Au, Hg, La, and In into either A or B, or both of them, in a compound expressed by a general formula ABO4 (where A represents In, Bi, Ga, or Gd and B represents Ta, Nb, or V).
    Type: Application
    Filed: March 13, 2012
    Publication date: April 24, 2014
    Applicant: IHI CORPORATION
    Inventors: Haruki Eguchi, Kenji Fuchigami
  • Patent number: 8691261
    Abstract: It is intended to provide a drug delivery system which makes it possible to solve the existing technical problems and is easily usable in practice. A drug, which comprises an organic compound or an inorganic compound and has been magnetized by modifying a side chain and/or crosslinking side chains, is induced by a magnetic force into target tissues or an affected part.
    Type: Grant
    Filed: July 18, 2012
    Date of Patent: April 8, 2014
    Assignees: IHI Corporation
    Inventors: Haruki Eguchi, Yoshihiro Ishikawa
  • Publication number: 20140046021
    Abstract: The molecular structures of metal-salen complexes which exerts pharmacological effects are clarified and the metal-salen complexes having such molecular structures and their derivatives are provided. A metal-salen complex compound is characterized in that a metal atom part in each of multiple molecules of the metal-salen complex or its derivative is multimerized via water.
    Type: Application
    Filed: January 19, 2012
    Publication date: February 13, 2014
    Applicants: IHI CORPORATION
    Inventors: Yoshihiro Ishikawa, Haruki Eguchi