Abstract: The present invention provides a receptacle used in a passive drug delivery system. The receptacle includes first flow path for supplying along a fluid conduit a medical liquid, second flow path for introducing the medical liquid into a container containing a beneficial agent, third flow path for delivering a mixed solution containing the medical liquid and agent, and a guide valve for controlling the flow path by closing or opening the flow path.

Abstract: The present invention provides an apparatus for introducing a reconstituted drug in a drug vial into a medical liquid while venting any gas within the vial to the atmosphere. The assembly includes a receptacle disposed in the middle of a fluid conduit for the medical fluid and which has an upper chamber and lower chamber. The assembly also has a cannula assembly which mounts upon and pierces a septum of the receptacle and also a pierceable stopper of the drug vial. The cannula assembly includes a pair of coaxial cannulas which pierce the stopper of the drug vial and establish a first flow path from the upper chamber to the drug vial and a second flow path from the drug vial to the lower chamber. The cannula assemble also includes a cannula that forms a vent passage in fluid communication with an upper portion of the vial, upon the piercing of the drug vial, with an end of the vent passage communicating with the atmosphere.

Abstract: The present invention provides a passive drug delivery apparatus which has a simplified structure. The present invention includes a junction member, disposed within the fluid conduit, for forming a first flow path to supply a medical liquid along the fluid conduit. A coupling member is provided, one end of which is to be coupled to the junction member, and the other end of which is to be inserted into a vial containing a beneficial agent. The coupling member includes structure to close the medical liquid flow path, a second flow path for introducing the medical liquid into the vial and a third flow path for delivering the mixed solution containing the medical liquid and agent.