Patents by Inventor Harvey Rabin

Harvey Rabin has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Treatment of neoplasms with viruses
    Patent number: 8105578
    Abstract: The subject invention relates to viruses that are able to replicate and thereby kill neoplastic cells with a deficiency in the IFN-mediated antiviral response, and their use in treating neoplastic disease including cancer and large tumors. RNA and DNA viruses are useful in this regard. The invention also relates to methods for the selection, design, purification and use of such viruses for cancer therapy.
    Type: Grant
    Filed: January 29, 2007
    Date of Patent: January 31, 2012
    Assignee: Wellstat Biologics Corporation
    Inventors: Michael S. Roberts, Robert M. Lorence, William S. Groene, Harvey Rabin, Reid W. von Borstel
  • Infection and treatment of neoplasms with vesicular stomatitis virus
    Patent number: 8043612
    Abstract: The subject invention relates to viruses that are able to replicate and thereby kill neoplastic cells with a deficiency in the IFN-mediated antiviral response, and their use in treating neoplastic disease including cancer and large tumors. RNA and DNA viruses are useful in this regard. The invention also relates to methods for the selection, design, purification and use of such viruses for cancer therapy.
    Type: Grant
    Filed: November 18, 2008
    Date of Patent: October 25, 2011
    Assignee: Wellstat Biologics Corporation
    Inventors: Michael S. Roberts, Robert M. Lorence, William S. Groene, Harvey Rabin, Reid W. von Borstel
  • Treatment of neoplasms with RNA viruses
    Patent number: 7780962
    Abstract: The subject invention relates to viruses that are able to replicate and thereby kill neoplastic cells with a deficiency in the IFN-mediated antiviral response, and their use in treating neoplastic disease including cancer and large tumors. RNA and DNA viruses are useful in this regard. The invention also relates to methods for the selection, design, purification and use of such viruses for cancer therapy.
    Type: Grant
    Filed: June 13, 2002
    Date of Patent: August 24, 2010
    Assignee: Wellstat Biologics Corporation
    Inventors: Michael S. Roberts, Robert M. Lorence, William S. Groene, Harvey Rabin, Reid W. von Borstel
  • Treatment of neoplasms with viruses
    Publication number: 20090081161
    Abstract: The subject invention relates to viruses that are able to replicate and thereby kill neoplastic cells with a deficiency in the IFN-mediated antiviral response, and their use in treating neoplastic disease including cancer and large tumors. RNA and DNA viruses are useful in this regard. The invention also relates to methods for the selection, design, purification and use of such viruses for cancer therapy.
    Type: Application
    Filed: November 18, 2008
    Publication date: March 26, 2009
    Applicant: Wellstat Biologics Corporation
    Inventors: Michael S. Roberts, Robert M. Lorence, William S. Groene, Harvey Rabin, Reid W. Von Borstel
  • Treatment of neoplasms with viruses
    Patent number: 7470426
    Abstract: The subject invention relates to viruses that are able to replicate and thereby kill neoplastic cells with a deficiency in the IFN-mediated antiviral response, and their use in treating neoplastic disease including cancer and large tumors. RNA and DNA viruses are useful in this regard. The invention also relates to methods for the selection, design, purification and use of such viruses for cancer therapy.
    Type: Grant
    Filed: April 17, 2000
    Date of Patent: December 30, 2008
    Assignee: Wellstat Biologics Corporation
    Inventors: Michael S. Roberts, Robert M. Lorence, William S. Groene, Harvey Rabin, Reid W. von Borstel
  • Treatment of neoplasms with viruses
    Publication number: 20080057037
    Abstract: The subject invention relates to viruses that are able to replicate and thereby kill neoplastic cells with a deficiency in the IFN-mediated antiviral response, and their use in treating neoplastic disease including cancer and large tumors. RNA and DNA viruses are useful in this regard. The invention also relates to methods for the selection, design, purification and use of such viruses for cancer therapy.
    Type: Application
    Filed: January 29, 2007
    Publication date: March 6, 2008
    Applicant: Pro-Virus, Inc.
    Inventors: Michael Roberts, Robert Lorence, William Groene, Harvey Rabin, Reid von Borstel
  • Newcastle disease virus administration
    Publication number: 20070077559
    Abstract: A mammalian subject having a tumor is treated by a method comprising administering an effective amount of a Newcastle disease virus, wherein the virus is administered to the subject in one or more cycles; and at least one cycle comprises administering sequentially one or more initial doses of from 1.8×1010 PFU to 4.8×1010 PFU of the virus per square meter of patient surface area followed by administering one or more subsequent doses of from 2.4×1010 PFU to 1.2×1011 PFU of the virus per square meter of patient surface area.
    Type: Application
    Filed: March 2, 2004
    Publication date: April 5, 2007
    Inventors: Michael Bamat, Robert Lorence, Pierre Major, Harvey Rabin, Michael Roberts
  • Treatment of neoplasms with viruses
    Publication number: 20030165465
    Abstract: The subject invention relates to viruses that are able to replicate and thereby kill neoplastic cells with a deficiency in the IFN-mediated antiviral response, and their use in treating neoplastic disease including cancer and large tumors. RNA and DNA viruses are useful in this regard. The invention also relates to methods for the selection, design, purification and use of such viruses for cancer therapy.
    Type: Application
    Filed: June 13, 2002
    Publication date: September 4, 2003
    Applicant: Pro-Virus, inc.
    Inventors: Michael S. Roberts, Robert M. Lorence, William S. Groene, Harvey Rabin, Reid W. von Borstel
  • Treatment of neoplasms with viruses
    Publication number: 20030044384
    Abstract: The subject invention relates to viruses that are able to replicate and thereby kill neoplastic cells with a deficiency in the IFN-mediated antiviral response, and their use in treating neoplastic disease including cancer and large tumors. RNA and DNA viruses are useful in this regard. The invention also relates to methods for the selection, design, purification and use of such viruses for cancer therapy.
    Type: Application
    Filed: January 15, 2002
    Publication date: March 6, 2003
    Applicant: Pro-Virus, Inc.
    Inventors: Michael S. Roberts, Robert M. Lorence, William S. Groene, Harvey Rabin, Reid W. von Borstel
  • Assay for detection and/or quantifying a mammalian IgA antibody response to Epstein-Barr virus membrane antigen using EBV-MA gp 350/220 lacking the transmembrane anchor domain
    Patent number: 5672471
    Abstract: This disclosure concerns an assay for detecting and/or quantifying a mammalian IgA antibody response to EBV-MA with an immobilized EBV-MA gp 350/220 lacking the transmembrane anchor domain.
    Type: Grant
    Filed: October 12, 1995
    Date of Patent: September 30, 1997
    Assignee: E. I. Du Pont de Nemours and Company
    Inventors: Paul John Durda, Elliott Dan Kieff, Gary Richard Pearson, Harvey Rabin, Marcia Delaney Sullivan
  • Test methods employing monoclonal antibodies against Herpes simplex virus types 1 and 2 nucleocapsids proteins
    Patent number: 4430437
    Abstract: The method of producing clinical assays for use of monoclonal antibodies in the diagnosis of Herpes simplex virus (HSV) infections and the differentiation of Herpes Simplex virus types 1 and 2 as a diagnostic kit for differentiating HSV-1 and HSV-2 utilizing clone 1D4 against HSV-1 and clone 3E1 against HSV-2.
    Type: Grant
    Filed: August 27, 1980
    Date of Patent: February 7, 1984
    Assignee: The United States of America as represented by the Department of Health and Human Services
    Inventors: Berge Hampar, Martin Zweig, Harvey Rabin, Conrad J. Heilman, Jr., Ralph F. Hopkins, III, Russell H. Neubauer