Patents by Inventor Harvey Schwam

Harvey Schwam has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Thiophene sulfonamide antiglaucoma agents
    Patent number: 4847289
    Abstract: Aryl (or aralkyl)-sulfonylthiophene-2-sulfonamides containing a basic functional group as a substituent are efficacious in the treatment of elevated intraocular pressure and glaucoma following topical ocular administration.
    Type: Grant
    Filed: June 8, 1987
    Date of Patent: July 11, 1989
    Assignee: Merck & Co., Inc.
    Inventors: John J. Baldwin, Charles M. Habecker, Samuel L. Graham, Wasyl Halczenko, George D. Hartman, Harvey Schwam, Gerald S. Ponticello, Kenneth L. Shepard
  • 5-Hydroxy-2-benzothiazolesulfonamide for the topical treatment of elevated intraocular pressure
    Patent number: 4454148
    Abstract: 5-Hydroxy-2-benzothiazolesulfonamide is useful for the topical treatment of elevated intraocular pressure. Ophthalmic compositions including drops and inserts are disclosed.
    Type: Grant
    Filed: December 9, 1982
    Date of Patent: June 12, 1984
    Assignee: Merck & Co., Inc.
    Inventors: Otto Woltersdorf, Jr., Harvey Schwam, Stuart R. Michelson, John M. Sondey
  • 6-Hydroxy-2-benzothiazolesulfonamide for the topical treatment of elevated intraocular pressure
    Patent number: 4386098
    Abstract: 6-Hydroxy-2-benzothiazolesulfonamide is useful for the topical treatment of elevated intraocular pressure. Ophthalmic compositions including drops and inserts are disclosed.
    Type: Grant
    Filed: November 3, 1981
    Date of Patent: May 31, 1983
    Assignee: Merck & Co., Inc.
    Inventors: Otto Woltersdorf, Jr., Stuart R. Michelson, John M. Sondey, Harvey Schwam
  • Synthetic antigens of luteinizing hormone releasing hormone
    Patent number: 3963691
    Abstract: Synthetic antigens related to luteinizing hormone-releasing hormone (hereinafter designated LH-RH) having the amino acid composition, pyroglutamyl-histidyl-tryptophanylseryl-tyrosyl-glycyl-leucyl-arginyl-prol yl-glycyl-poly-L-lysine (hereinafter designated pyroglu-his-trp-ser-tyr-glyleu-arg-pro-gly-poly-L-lys) and poly-L-lysyl-glutarylhistidyl-tryptophanyl-seryl-tyrosyl-glycyl-leucyl-arg inylprolyl-glycine amide (hereinafter designated poly-L-lysglutaryl-his-trp-ser-tyr-gly-leu-arg-pro-gly) are prepared by coupling the corresponding decapeptide with poly-L-lysine. The corresponding decapeptides are prepared by controlled stepwise procedures starting with individual amino acid components. These antigens have the property of inducing formation of antibodies to luteinizing hormone-releasing hormone (LH-RH) in animals.
    Type: Grant
    Filed: October 7, 1974
    Date of Patent: June 15, 1976
    Assignee: Merck & Co., Inc.
    Inventors: Carl H. Hoffman, Harvey Schwam, Stephen F. Brady, Martin Hichens, Ruth F. Nutt