Patents by Inventor Hatsuo Kawada

Hatsuo Kawada has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • CYCLIC COMPOUND HAVING SELECTIVE INHIBITORY ACTION ON KRAS OVER HRAS AND NRAS
    Publication number: 20240158446
    Abstract: Cyclic compounds and oligopeptide compounds that selectively inhibit KRAS were found. Oligopeptide compounds and non-natural amino acids useful for producing a cyclic compound were also found. Moreover, cyclic compounds and oligopeptide compounds were found to interact with an amino acid residue specific to KRAS.
    Type: Application
    Filed: May 6, 2022
    Publication date: May 16, 2024
    Inventors: Hatsuo KAWADA, Koji TAKANO, Tomoya KOTAKE, Mirai KAGE, Satoshi HASHIMOTO, Minoru TAMIYA, Yuma WAKAMIYA, Ryuji HAYASHI, Yuya MORITA
  • TETRACYCLIC COMPOUND
    Publication number: 20230142119
    Abstract: A compound represented by the general Formula (I) below, or a salt or solvate thereof, which is useful as an ALK inhibitor, and is useful for prophylaxis or treatment of a disease accompanied by abnormality in ALK, for example, cancer, cancer metastasis, depression or cognitive function disorder: (meanings of the symbols that are included in the formula are as given in the specification).
    Type: Application
    Filed: July 8, 2022
    Publication date: May 11, 2023
    Applicant: Chugai Seiyaku Kabushiki Kaisha
    Inventors: Kazutomo KINOSHITA, Kohsuke ASOH, Noriyuki FURUICHI, Toshiya ITO, Hatsuo KAWADA, Nobuya ISHII, Hiroshi SAKAMOTO, WooSang HONG, MinJeong PARK, Yoshiyuki ONO, Yasuharu KATO, Kenji MORIKAMI, Takashi EMURA, Nobuhiro OIKAWA
  • TETRACYCLIC COMPOUND
    Publication number: 20220306578
    Abstract: A compound represented by the general Formula (I) below, or a salt or solvate thereof, which is useful as an ALK inhibitor, and is useful for prophylaxis or treatment of a disease accompanied by abnormality in ALK, for example, cancer, cancer metastasis, depression or cognitive function disorder: (meanings of the symbols that are included in the formula are as given in the specification).
    Type: Application
    Filed: April 29, 2020
    Publication date: September 29, 2022
    Applicant: Chugai Seiyaku Kabushiki Kaisha
    Inventors: Kazutomo KINOSHITA, Kohsuke ASOH, Noriyuki FURUICHI, Toshiya ITO, Hatsuo KAWADA, Nobuya ISHII, Hiroshi SAKAMOTO, WooSang HONG, MinJeong PARK, Yoshiyuki ONO, Yasuharu KATO, Kenji MORIKAMI, Takashi EMURA, Nobuhiro OIKAWA
  • TETRACYCLIC COMPOUND
    Publication number: 20200017442
    Abstract: A compound represented by the general Formula (I) below, or a salt or solvate thereof, which is useful as an ALK inhibitor, and is useful for prophylaxis or treatment of a disease accompanied by abnormality in ALK, for example, cancer, cancer metastasis, depression or cognitive function disorder: (meanings of the symbols that are included in the formula are as given in the specification).
    Type: Application
    Filed: January 4, 2019
    Publication date: January 16, 2020
    Applicant: Chugai Seiyaku Kabushiki Kaisha
    Inventors: Kazutomo KINOSHITA, Kohsuke ASOH, Noriyuki FURUICHI, Toshiya ITO, Hatsuo KAWADA, Nabuya ISHII, Hiroshi SAKAMOTO, WooSang HONG, MinJeong PARK, Yoshiyuki ONO, Yasuharu KATO, Kenji MORIKAMI, Takashi EMURA, Nobuhiro OIKAWA
  • Quinazolinone and isoquinolinone derivative
    Patent number: 10005739
    Abstract: The present invention relates to quinazolinone and isoquinolinone derivatives represented by formula (I) or pharmaceutically acceptable salts thereof.
    Type: Grant
    Filed: October 23, 2014
    Date of Patent: June 26, 2018
    Assignee: CHUGAI SEIYAKU KABUSHIKI KAISHA
    Inventors: Takeshi Murata, Sousuke Hara, Satoshi Niizuma, Kihito Hada, Hatsuo Kawada, Masahiro Sakaitani, Hideaki Shimada, Yoshito Nakanishi
  • Benzamide derivative
    Patent number: 9695118
    Abstract: The present invention relates to benzamide derivatives represented by formula (I) or pharmaceutically acceptable salts thereof.
    Type: Grant
    Filed: April 24, 2013
    Date of Patent: July 4, 2017
    Assignee: Chugai Seiyaku Kabushiki Kaisha
    Inventors: Takeshi Murata, Satoshi Niizuma, Sousuke Hara, Hatsuo Kawada, Kihito Hada, Hideaki Shimada, Hiroshi Tanaka, Yoshito Nakanishi
  • Quinazolinedione derivative
    Patent number: 9567304
    Abstract: The present invention relates to quinazolinedione derivatives represented by formula (I) or pharmaceutically acceptable salts thereof.
    Type: Grant
    Filed: April 24, 2013
    Date of Patent: February 14, 2017
    Assignee: Chugai Seiyaku Kabushiki Kaisha
    Inventors: Takeshi Murata, Hatsuo Kawada, Satoshi Niizuma, Sousuke Hara, Kihito Hada, Hideaki Shimada, Hiroshi Tanaka, Toshiyuki Mio
  • TETRACYCLIC COMPOUND
    Publication number: 20160340308
    Abstract: A compound represented by the general Formula (I) below, or a salt or solvate thereof, which is useful as an ALK inhibitor, and is useful for prophylaxis or treatment of a disease accompanied by abnormality in ALK, for example, cancer, cancer metastasis, depression or cognitive function disorder: (meanings of the symbols that are included in the formula are as given in the specification).
    Type: Application
    Filed: July 28, 2016
    Publication date: November 24, 2016
    Applicant: Chugai Seiyaku Kabushiki Kaisha
    Inventors: Kazutomo Kinoshita, Kohsuke ASOH, Noriyuki FURUICHI, Toshiya ITO, Hatsuo KAWADA, Nobuya ISHll, Hiroshi SAKAMOTO, WooSang HONG, MinJeong PARK, Yoshiyuki ONO, Yasuharu KATO, Kenji MORIKAMI, Takashi EMURA, Nobuhiro OIKAWA
  • QUINAZOLINONE AND ISOQUINOLINONE DERIVATIVE
    Publication number: 20160272595
    Abstract: The present invention relates to quinazolinone and isoquinolinone derivatives represented by formula (I) or pharmaceutically acceptable salts thereof.
    Type: Application
    Filed: October 23, 2014
    Publication date: September 22, 2016
    Applicant: CHUGAI SEIYAKU KABUSHIKI KAISHA
    Inventors: Takeshi MURATA, Sousuke HARA, Satoshi NIIZUMA, Kihito HADA, Hatsuo KAWADA, Masahiro SAKAITANI, Hideaki SHIMADA, Yoshito NAKANISHI
  • Tetracyclic compound
    Patent number: 9440922
    Abstract: A compound represented by the general Formula (I) below, or a salt or solvate thereof, which is useful as an ALK inhibitor, and is useful for prophylaxis or treatment of a disease accompanied by abnormality in ALK, for example, cancer, cancer metastasis, depression or cognitive function disorder: (meanings of the symbols that are included in the formula are as given in the specification).
    Type: Grant
    Filed: February 11, 2015
    Date of Patent: September 13, 2016
    Assignee: Chugai Seiyaku Kabushiki Kaisha
    Inventors: Kazutomo Kinoshita, Kohsuke Asoh, Noriyuki Furuichi, Toshiya Ito, Hatsuo Kawada, Nobuya Ishii, Hiroshi Sakamoto, WooSang Hong, MinJeong Park, Yoshiyuki Ono, Yasuharu Kato, Kenji Morikami, Takashi Emura, Nobuhiro Oikawa
  • Tetracyclic compound
    Patent number: 9126931
    Abstract: A compound represented by the general Formula (I) below, or a salt or solvate thereof, which is useful as an ALK inhibitor, and is useful for prophylaxis or treatment of a disease accompanied by abnormality in ALK, for example, cancer, cancer metastasis, depression or cognitive function disorder: (meanings of the symbols that are included in the formula are as given in the specification).
    Type: Grant
    Filed: June 9, 2010
    Date of Patent: September 8, 2015
    Assignee: Chugai Seiyaku Kabushiki Kaisha
    Inventors: Kazutomo Kinoshita, Kohsuke Asoh, Noriyuki Furuichi, Toshiya Ito, Hatsuo Kawada, Nobuya Ishii, Hiroshi Sakamoto, WooSang Hong, MinJeong Park, Yoshiyuki Ono, Yasuharu Kato, Kenji Morikami, Takashi Emura, Nobuhiro Oikawa
  • BENZAMIDE DERIVATIVE
    Publication number: 20150152047
    Abstract: The present invention relates to benzamide derivatives represented by formula (I) or pharmaceutically acceptable salts thereof.
    Type: Application
    Filed: April 24, 2013
    Publication date: June 4, 2015
    Inventors: Takeshi Murata, Satoshi Niizuma, Sousuke Hara, Hatsuo Kawada, Kihito Hada, Hideaki Shimada, Hiroshi Tanaka, Yoshito Nakanishi
  • TETRACYCLIC COMPOUND
    Publication number: 20150150845
    Abstract: A compound represented by the general Formula (I) below, or a salt or solvate thereof, which is useful as an ALK inhibitor, and is useful for prophylaxis or treatment of a disease accompanied by abnormality in ALK, for example, cancer, cancer metastasis, depression or cognitive function disorder: (meanings of the symbols that are included in the formula are as given in the specification).
    Type: Application
    Filed: February 11, 2015
    Publication date: June 4, 2015
    Applicant: Chugai Seiyaku Kabushiki Kaisha
    Inventors: Kazutomo KINOSHITA, Kohsuke ASOH, Noriyuki FURUICHI, Toshiya ITO, Hatsuo KAWADA, Nobuya ISHII, Hiroshi SAKAMOTO, WooSang HONG, MinJeong PARK, Yoshiyuki ONO, Yasuharu KATO, Kenji MORIKAMI, Takashi EMURA, Nobuhiro OIKAWA
  • QUINAZOLINEDIONE DERIVATIVE
    Publication number: 20150141400
    Abstract: The present invention relates to quinazolinedione derivatives represented by formula (I) or pharmaceutically acceptable salts thereof.
    Type: Application
    Filed: April 24, 2013
    Publication date: May 21, 2015
    Inventors: Takeshi Murata, Hatsuo Kawada, Satoshi Niizuma, Sousuke Hara, Kihito Hada, Hideaki Shimada, Hiroshi Tanaka, Toshiyuki Mio
  • TETRACYCLIC COMPOUND
    Publication number: 20120083488
    Abstract: A compound represented by the general Formula (I) below, or a salt or solvate thereof, which is useful as an ALK inhibitor, and is useful for prophylaxis or treatment of a disease accompanied by abnormality in ALK, for example, cancer, cancer metastasis, depression or cognitive function disorder: (meanings of the symbols that are included in the formula are as given in the specification).
    Type: Application
    Filed: June 9, 2010
    Publication date: April 5, 2012
    Inventors: Kazutomo Kinoshita, Kohsuke Asoh, Noriyuki Furuichi, Toshiya Ito, Hatsuo Kawada, Nobuya Ishii, Hiroshi Sakamoto, WooSang Hong, MinJeong Park, Yoshiyuki Ono, Yashuharu Kato, Kenji Morikami, Takashi Emura, Nobuhiro Oikawa
  • Pyrimidine derivatives as PI3K inhibitor and use thereof
    Patent number: 8022205
    Abstract: A drug is provided that is useful as a preventive or therapeutic for cancer as a result of having superior PI3K inhibitory effects as well as superior stability in the body and water-solubility. A compound, or pharmaceutically acceptable salt thereof, represented by formula (I): [wherein, X represents a single bond, etc.; Y represents a single bond, etc. (provided that X and Y are not simultaneously single bonds); Z represents a hydrogen atom, etc.; m represents an integer of 1 or 2; and R1 represents a cyclic substituent].
    Type: Grant
    Filed: August 7, 2007
    Date of Patent: September 20, 2011
    Assignee: Chugai Seiyaku Kabushiki Kaisha
    Inventors: Nobuo Shimma, Hirosato Ebiike, Jun Ohwada, Hatsuo Kawada, Kenji Morikami, Mitsuaki Nakamura, Miyuki Yoshida, Nobuya Ishii, Masami Hasegawa, Shun Yamamoto, Kohei Koyama
  • PYRIMIDINE DERIVATIVES AS PI3K INHIBITOR AND USE THEREOF
    Publication number: 20100069629
    Abstract: A drug is provided that is useful as a preventive or therapeutic for cancer as a result of having superior PI3K inhibitory effects as well as superior stability in the body and water-solubility. A compound, or pharmaceutically acceptable salt thereof, represented by formula (I): [wherein, X represents a single bond, etc.; Y represents a single bond, etc. (provided that X and Y are not simultaneously single bonds); Z represents a hydrogen atom, etc.; m represents an integer of 1 or 2; and R1 represents a cyclic substituent].
    Type: Application
    Filed: August 7, 2007
    Publication date: March 18, 2010
    Inventors: Nobuo Shimma, Hirosato Ebiike, Jun Ohwada, Hatsuo Kawada, Kenji Morikami, Mitsuaki Nakamura, Miyuki Yoshida, Nobuya Ishii, Masami Hasegawa, Shun Yamamoto, Kohei Koyama