Patents by Inventor Hayato YABUUCHI

Hayato YABUUCHI has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Compound usable as cationic lipid
    Patent number: 11471533
    Abstract: The present invention provides a compound represented by formula (I) usable as a cationic lipid that facilitates introduction of a nucleic acid, for example, into a cell, and a composition or the like containing the compound.
    Type: Grant
    Filed: September 27, 2017
    Date of Patent: October 18, 2022
    Assignee: KYOWA KIRIN CO., LTD.
    Inventors: Shintaro Hosoe, Hayato Yabuuchi
  • COMPOUND USABLE AS CATIONIC LIPID
    Publication number: 20210275672
    Abstract: The present invention provides a compound represented by formula (I) usable as a cationic lipid that facilitates introduction of a nucleic acid, for example, into a cell, and a composition or the like containing the compound.
    Type: Application
    Filed: September 27, 2017
    Publication date: September 9, 2021
    Applicant: Kyowa Hakko Kirin Co., Ltd.
    Inventors: Shintaro HOSOE, Hayato YABUUCHI
  • RNAi PHARMACEUTICAL COMPOSITION FOR SUPPRESSING EXPRESSION OF CKAP5 GENE
    Publication number: 20170101639
    Abstract: The present invention provides a composition for suppressing the expression of the CKAP5 gene, the composition comprising a lipid particle containing a double-stranded nucleic acid as a drug and a cationic lipid, the double-stranded nucleic acid having an antisense strand having a base sequence complementary to the sequence of at least 19 continuous bases in CKAP5 gene mRNA of any one of SEQ ID NOs: 1 to 6, the cationic lipid being represented by formula (I): wherein R1 and R2 are the same or different and are each linear or branched alkyl, alkenyl or alkynyl of 12 to 24 carbon atoms; L1 and L2 are the same or different and are each —CO—O— or —O—CO—; a and b are the same or different and are each 1 to 3; and R3 is a hydrogen atom, alkyl of 1 to 6 carbon atoms, or alkenyl of 3 to 6 carbon atoms; a medicament comprising the composition, and the like.
    Type: Application
    Filed: June 4, 2015
    Publication date: April 13, 2017
    Applicants: Kyowa Hakko Kirin Co., Ltd., DICERNA PHARMACEUTICALS, INC.
    Inventors: Hayato YABUUCHI, Kana KURIHARA, Ayumi YAMADA, Keiko NAKAHASHI, Kentaro HATANAKA, Shiho TOMURA