Patents by Inventor Hazel Joan HUNT

Hazel Joan HUNT has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • POLYMORPHS OF PYRIMIDINE CYCLOHEXYL GLUCOCORTICOID RECEPTOR MODULATORS
    Publication number: 20240083856
    Abstract: The present invention provides crystalline forms of (E)-6-(4-Phenylcyclohexyl)-5-(3-trifluoromethylbenzyl)-1H-pyrimidine-2,4-dione, and methods of making and using the same.
    Type: Application
    Filed: August 7, 2023
    Publication date: March 14, 2024
    Inventors: Hazel Joan Hunt, Lorraine Donaghy, Keith Lorimer, Nathan Jay Dixon, Jeffrey Mark Dener
  • METHODS OF PREPARING HETEROARYL-KETONE FUSED AZADECALIN GLUCOCORTICOID RECEPTOR MODULATORS
    Publication number: 20230416250
    Abstract: The present invention provides methods of preparing heteroaryl-ketone fused azadecalin glucocorticoid receptor modulators, and compositions having low impurity levels.
    Type: Application
    Filed: June 27, 2023
    Publication date: December 28, 2023
    Inventors: Hazel Joan Hunt, Gary Patrick Reid, Jeffrey Mark Dener, Adam Daisuke Gammack Yamagata, Gareth C. Sheppard
  • Method of preparing pyrimidine cyclohexyl glucocorticoid receptor modulators
    Patent number: 11827608
    Abstract: The present invention provides methods of preparing 2-amino-6-((1r,4r)-4-phenylcyclohexyl)-5-(3-(trifluoromethyl)benzyl)pyrimidin-4(3H)-one, and 2-amino-6-((1r,4r)-4-phenylcyclohexyl)-5-(3-(trifluoromethyl)benzyl)pyrimidin-4(3H)-one monohydrate, as well as new intermediate compounds.
    Type: Grant
    Filed: December 20, 2021
    Date of Patent: November 28, 2023
    Assignee: CORCEPT THERAPEUTICS INCORPORATED
    Inventors: Jeffrey Mark Dener, Hazel Joan Hunt, Nicholas David Tyrrell
  • Polymorphs of pyrimidine cyclohexyl glucocorticoid receptor modulators
    Patent number: 11760731
    Abstract: The present invention provides crystalline forms of (E)-6-(4-Phenylcyclohexyl)-5-(3-trifluoromethylbenzyl)-1H-pyrimidine-2,4-dione, and methods of making and using the same.
    Type: Grant
    Filed: December 5, 2022
    Date of Patent: September 19, 2023
    Assignee: Corcept Therapeutics Incorporated
    Inventors: Hazel Joan Hunt, Lorraine Donaghy, Keith Lorimer, Nathan Jay Dixon, Jeffrey Mark Dener
  • BICYCLIC INDAZOLE GLUCOCORTICOID RECEPTOR ANTAGONISTS
    Publication number: 20230242514
    Abstract: The present disclosure provides compounds of Formula I, Ia, Ib, Ib-1, Ib-2, Ic, Ic-1, Id-1, and Id-2. Compounds of Formula I, Ia, Ib, Ib-1, Ib-2, Ic, Ic-1, Id-1, and Id-2 may be used in pharmaceutical formulations, and may be used for modulating glucocorticoid receptors.
    Type: Application
    Filed: December 20, 2022
    Publication date: August 3, 2023
    Inventors: Lorna Duffy, Thomas Hornsby, Morgan Jouanneau, Mark Mills, Andrew William Phillips, Andrew James Smith, Hazel Joan Hunt, Peter Hunt
  • POLYMORPHS OF PYRIMIDINE CYCLOHEXYL GLUCOCORTICOID RECEPTOR MODULATORS
    Publication number: 20230212128
    Abstract: The present invention provides crystalline forms of (E)-6-(4-Phenylcyclohexyl)-5-(3-trifluoromethylbenzyl)-1H-pyrimidine-2,4-dione, and methods of making and using the same.
    Type: Application
    Filed: December 5, 2022
    Publication date: July 6, 2023
    Inventors: Hazel Joan Hunt, Lorraine Donaghy, Keith Lorimer, Nathan Jay Dixon, Jeffrey Mark Dener
  • PIPERAZINE INDAZOLE GLUCOCORTICOID RECEPTOR ANTAGONISTS
    Publication number: 20230192666
    Abstract: The present disclosure provides piperazine substituted fused azadecalin compounds of Formula J, I, Ia, Ib, Ib-1, Ib-2, Ic and Id for use in pharmaceutical formulations, and for modulating glucocorticoid receptors.
    Type: Application
    Filed: December 20, 2022
    Publication date: June 22, 2023
    Inventors: Mark Mills, Andrew William Phillips, Bohdan Waszkowycz, Hazel Joan Hunt, Angus Morrison, Angelo Pugliese, Jonathan Gillespie, Euan Fordyce
  • Polymorphs of pyrimidine cyclohexyl glucocorticoid receptor modulators
    Patent number: 11548856
    Abstract: The present invention provides crystalline forms of (E)-6-(4-Phenylcyclohexyl)-5-(3-trifluoromethylbenzyl)-1H-pyrimidine-2,4-dione, and methods of making and using the same.
    Type: Grant
    Filed: May 5, 2021
    Date of Patent: January 10, 2023
    Assignee: Corcept Therapeutics Incorporated
    Inventors: Hazel Joan Hunt, Lorraine Donaghy, Keith Lorimer, Nathan Jay Dixon, Jeffrey Mark Dener
  • METHODS OF PREPARING HETEROARYL-KETONE FUSED AZADECALIN GLUCOCORTICOID RECEPTOR MODULATORS
    Publication number: 20220227753
    Abstract: The present invention provides methods of preparing heteroaryl-ketone fused azadecalin glucocorticoid receptor modulators, and compositions having low impurity levels.
    Type: Application
    Filed: December 22, 2021
    Publication date: July 21, 2022
    Inventors: Jeffrey Mark DENER, Hazel Joan HUNT, Travis LEMONS, Gary REID, Kilian GARREC, Thomas C. STEPHENS, Adam Daisuke GAMMACK YAMAGATA, Yunguo LU
  • METHOD OF PREPARING PYRIMIDINE CYCLOHEXYL GLUCOCORTICOID RECEPTOR MODULATORS
    Publication number: 20220220081
    Abstract: The present invention provides methods of preparing 2-amino-6-((1r,4r)-4-phenylcyclohexyl)-5-(3-(trifluoromethyl)benzyl)pyrimidin-4(3H)-one, and 2-amino-6-((1r,4r)-4-phenylcyclohexyl)-5-(3-(trifluoromethyl)benzyl)pyrimidin-4(3H)-one monohydrate, as well as new intermediate compounds.
    Type: Application
    Filed: December 20, 2021
    Publication date: July 14, 2022
    Inventors: Jeffrey Mark Dener, Hazel Joan Hunt, Nicholas David Tyrrell
  • POLYMORPHS OF PYRIMIDINE CYCLOHEXYL GLUCOCORTICOID RECEPTOR MODULATORS
    Publication number: 20210363112
    Abstract: The present invention provides crystalline forms of (E)-6-(4-Phenylcyclohexyl)-5-(3-trifluoromethylbenzyl)-1H-pyrimidine-2,4-dione, and methods of making and using the same.
    Type: Application
    Filed: May 5, 2021
    Publication date: November 25, 2021
    Inventors: Hazel Joan HUNT, Lorraine DONAGHY, Keith LORIMER, Nathan Jay DIXON, Jeffrey Mark DENER