Abstract: The present disclosure relates to a novel PLK1 degradation inducing compound having a structure according to Formula I, a method for preparing the same, and the use thereof. The compounds of the present disclosure exhibit an effect of inducing PLK1 degradation. Therefore, the compounds of the present disclosure may be effectively utilized for preventing or treating PLK1-related diseases.

Abstract: A secondary battery has a structure including an internal core portion containing an electrolyte having a relatively lower crosslinking degree, and surrounded with a peripheral portion containing an electrolyte having a relatively higher crosslinking degree. It is possible to provide an effect of improving both ion conductivity and mechanical properties by virtue of such structural characteristics. The electrolyte portion having a lower crosslinking degree is confined by the electrolyte having a higher crosslinking degree to provide an effect of preventing electrolyte leakage. The secondary battery can be obtained by a simple method that includes crosslinking only the peripheral portion before the core portion reaches to a crosslinking temperature and is crosslinked under an environment preheated to the crosslinking temperature or higher. As a result, there is no adverse effect upon the processing efficiency, since any separate device or system line is not required to carry out the crosslinking.

Abstract: An optical phased array (OPA) radiator includes a plurality of unit radiators configured to serve as optical waveguides, each of the unit radiators being made of a silicon material and each having a predetermined length, where the unit radiators are disposed in parallel; a cladding portion configured to cover the plurality of unit radiators; and a plurality of electrodes arranged in parallel with the plurality of unit radiators on the cladding portion, where the plurality of electrodes are arranged so as not to overlap the plurality of unit radiators in a vertical direction. A beam radiated through the unit radiators using a phased array can be efficiently vertically steered.

Abstract: The present invention relates to a process for the purification of fluorinated olefins, in particular hexafluoro-1,3-butadiene, comprising a step wherein a liquid mixture comprising hexafluoro-1,3-butadiene in liquid phase is contacted with at least one adsorbent having an average pore size of less than 10 ?.

Abstract: Provided are a lithium secondary battery and a manufacturing method thereof capable of improving the lifespan properties and high-temperature storage properties of the lithium secondary battery, wherein the lithium secondary battery includes a positive electrode including a positive electrode active material layer containing a positive electrode active material and one or more additives selected from succinonitrile (SN), propane sultone (PS), and propene sultone (PRS). The lithium secondary battery further includes a negative electrode, a separator interposed between the positive electrode and the negative electrode, and a gel polymer electrolyte, wherein the additive is included in an amount of 0.2 parts by weight to 5.0 parts by weight based on 100 parts by weight of the positive electrode active material layer.

Abstract: Provided are an organic light-emitting panel and an organic light-emitting display device including the same. In the organic light-emitting panel, a planarization layer has at least one contact holes in an active area, and first inclination of a first side surface of the planarization layer, located in the non-active area and closest to a dam, with respect to the top surface of the substrate is smaller than a second inclination of a second side surface of the planarization layer, surrounding the contact hole, with respect to the top surface of the substrate.

Abstract: Methods of producing cured CO2 sequestering solid compositions, e.g., precipitate or aggregate compositions, are provided. Aspects of the methods include preparing an initial CO2 sequestering solid composition, and then contacting the initial composition with a curing liquid sufficient to produce a cured CO2 sequestering solid composition. Also provided are systems for performing the methods and cured CO2 sequestering solid compositions produced therefrom.

Abstract: A battery pack, a manufacturing method thereof, and a method for replacing a battery cell of the battery pack are provided. The battery pack includes a battery pack housing, a plurality of battery cells in the battery pack housing, and a fixing unit in the battery pack housing and configured to fix a position of the plurality of battery cells by a magnetic force.

Abstract: The present invention relates to a ternary catalyst for carbon dioxide reduction, the catalyst including Au and Cu, and further including In or Mo, wherein the content of In or Mo is 0.1 at % to 3 at %.

Abstract: The present invention relates to a culture medium composition for culturing keratinocytes, and more specifically, to a culture medium composition for establishing or culturing keratinocytes, comprising calcium, an epidermal growth factor, and albumin According to the present invention, when keratinocytes are cultured using the culture medium of the present invention, the keratinocytes can be effectively proliferated within a short time, thus making it possible to more quickly obtain a desired number of the cells during the development of a therapeutic agent using the keratinocytes, and the activity of the keratinocytes is improved, and thus the culture medium of the present invention can be useful in the fields of keratinocyte research and the development of therapeutic agents.

Abstract: The present invention relates to a culture medium composition obtained by further adding at least one selected from the group consisting of rotenone and albumin to a serum-free medium prepared through a CAMPs technology. It has been ascertained that the proliferation of dermal papilla cells and maintenance of characteristics thereof during culturing can be improved by regulating the concentration of rotenone and albumin, and since the culture medium composition is a serum-free chemical medium comprising no serum, there is no risk of side effects, which can be caused by using a conventional serum medium, during use on the human body. The culture medium composition of the present invention obtained by further adding at least one selected from the group consisting of rotenone and albumin to a serum-free medium, or dermal papilla cells cultured through the composition can be effectively used in the development of therapeutic agents for hair loss prevention and hair growth promotion.

Abstract: An exemplary semiconductor device can comprise (a) a substrate comprising a substrate dielectric structure between the substrate top side and the substrate bottom side, conductive pads at the substrate bottom side, and a substrate cavity through the substrate dielectric structure, (b) a base electronic component comprising inner short bumps; outer short bumps bounding a perimeter around the inner short bumps, and tall bumps between the outer short bumps and an edge of the base component top side, and (c) a mounted electronic component coupled to the inner short bumps of the base electronic component. The tall bumps of the base component can be coupled to the conductive pads of the substrate. The mounted electronic component can be located in the substrate cavity. The substrate bottom side can cover at least a portion of the outer short bumps of the base electronic component. Other examples and related methods are disclosed herein.

Abstract: A dry electrode composition including: an electrode active material; a particulate binder in which fibers aggregate to form bundles; and a plasticizer, wherein the binder is fiberizable by heat and pressure, a method for manufacturing a dry electrode sheet for a secondary battery using the dry electrode composition, and an electrode and a secondary battery including the dry electrode sheet are provided.

Abstract: A method of manufacturing a dry electrode sheet for a secondary battery includes providing a dry electrode composition comprising an electrode active material and a binder, a calendering operation of preparing an electrode sheet by passing the dry electrode composition through a calender roll including three or more rolls. The calendering operation includes a first electrode sheet manufacturing operation of manufacturing a first electrode sheet by injecting the dry electrode composition between two adjacent rolls spaced apart from each other by a first interval W1, and an electrode sheet manufacturing operation of manufacturing a dry electrode sheet by inserting the first electrode sheet between two adjacent rolls spaced apart from each other by a second interval W2. The first interval W1 and the second interval W2 have a compression rate of 0.10 or more and 0.65 or less, represented by the equation (1) compression rate=(W1?W2)/W1.

Abstract: A method of manufacturing a dry electrode sheet for a secondary battery includes providing a dry electrode composition including an electrode active material and a binder, kneading the dry electrode composition, and manufacturing an electrode sheet by calendering the kneaded dry electrode composition.

Abstract: Disclosed is an item list management method comprising checking a first list including at least one item selected according to a selection input of a user, checking a first sub-list and a second sub-list in which the at least one item is classified based on a time when the at least one item is stored in the first list, and providing, in response to a first input of the user related to the first list, a first page including the first sub-list displayed in a first area and the second sub-list displayed in a second area distinct from the first area.

Abstract: A method of manufacturing a dry electrode sheet for a secondary battery includes providing a dry electrode composition comprising an active electrode material and a binder, calendering the dry electrode composition with a calender roll and forming a first electrode sheet, cutting the first electrode sheet into two or more pieces, and laminating and then calendering the cut first electrode sheet.

Abstract: The circuit breaker control module of the present disclosure comprises: a plurality of semiconductor switching units for blocking current flows of transmission distribution lines or performing switching operations so as to switch the current flow directions; a control unit for controlling the turn-on/turn-off operation of each semiconductor switching unit by transmitting a trip signal to each of the plurality of semiconductor switching units; and a plurality of insulation type signal transmission element units which are provided between the plurality of semiconductor switching units and the control unit such that the semiconductor switching units and the control unit are insulated, and which transmit the trip signal from the control unit to each of the plurality of semiconductor switching units, and thus the presently disclosed circuit breaker control module can reduce the risk of accidents due to an electrical arc and increase the stability and reliability of the control unit.

Abstract: A refrigerator is proposed. The refrigerator includes a refrigerating compartment, a freezing compartment, and an ice-making compartment. The refrigerating compartment is configured to receive cool air from a refrigerating compartment side grill fan assembly, and the ice-making compartment is configured to be located any one refrigerating compartment door and to receive cool air from a freezing compartment side grill fan assembly with the freezing compartment. The refrigerating compartment side grill fan assembly is configured to supply a greater amount of cool air to the side where the ice-making compartment and the refrigerating compartment side grill fan assembly are located, and to perform cool air supply proportional to temperature influence provided from the ice-making compartment and the refrigerating compartment side grill fan assembly.

Abstract: Provided a gas diffusion layer for fuel cells, the gas diffusion layer including: a carbon substrate; and a microporous layer formed on the carbon substrate, wherein the microporous layer comprises first carbon particles having a partially graphitized structure and a water-repellent binder resin binding the first carbon particles, and the microporous layer further comprises a cerium compound, a nitrogen-doped cerium compound, nitrogen-doped second carbon particles having a partially graphitized or non-graphitized structure, or a mixture of two or more, as a radical scavenger capable of removing hydrogen peroxide generated at a fuel cell open circuit potential or a higher potential.