Abstract: The present disclosure provides systems, apparatuses, and methods for generating images of the human body by solid-state magnetic resonance imaging. An example method can comprise receiving first imaging data at two or more echo times taken with a first radiofrequency configuration, receiving second imaging data at two or more echo times taken with a second radiofrequency configuration. An example method can comprise generating, based on at least the first imaging data and the second imaging data, two or more k-space datasets. An example method can comprise generating, based on at least the two or more k-space datasets, one or more images. The one or more images can comprise different image contrast.

Abstract: A method for non-contrast enhanced 4D time resolved dynamic magnetic resonance angiography using arterial spin labeling of blood water as an endogenous tracer and a multiphase balanced steady state free precession readout is presented. Imaging can be accelerated with dynamic golden angle radial acquisitions and k-space weighted imaging contrast (KWIC) image reconstruction and it can be used with parallel imaging techniques. Quantitative tracer kinetic models can be formed allowing cerebral blood volume, cerebral blood flow and mean transit time to be estimated. Vascular compliance can also be assessed using 4D dMRA by synchronizing dMRA acquisitions with the systolic and diastolic phases of the cardiac cycle.

Abstract: A method for non-contrast enhanced 4D time resolved dynamic magnetic resonance angiography using arterial spin labeling of blood water as an endogenous tracer and a multiphase balanced steady state free precession readout is presented. Imaging can be accelerated with dynamic golden angle radial acquisitions and k-space weighted imaging contrast (KWIC) image reconstruction and it can be used with parallel imaging techniques. Quantitative tracer kinetic models can be formed allowing cerebral blood volume, cerebral blood flow and mean transit time to be estimated. Vascular compliance can also be assessed using 4D dMRA by synchronizing dMRA acquisitions with the systolic and diastolic phases of the cardiac cycle.

Abstract: A technique for correcting translational and rotational motion of an object, such as an object in a magnetic field, utilizes the k-space representation of the object. An initial region in the k-space representation is used as a motion-free reference region, indicative of the motion-free object. Motion-free data adjacent to the initial region are then estimated by extrapolating from the initial region, and the extrapolated data are subsequently used to estimate motion by correlating it with actual data. Segments adjacent to the initial region are then motion corrected and incorporated into an expanding base region. The expanded base region is used in subsequent correction steps. This process is continued until the entire k-space is motion-corrected. Two different extrapolation methods were used for the purpose of motion estimation: edge enhancement and finite-support solution. One technique is utilized near the k-space center and the other is utilized in the outer k-space regions.

Abstract: Provided is a method for rapid, 3D, dynamic, projection reconstruction bilateral breast imaging using simultaneous multi-slab volume excitation and radial acquisition of a contrast enhanced bilateral image, in conjunction with SENSE processing, using k-Space Weighted Image Contrast (“KWIC”) filtering and multi-coil arrays for signal separation in an interleaved bilateral MR bilateral breast scan that uses conventional Cartesian sampling without parallel imaging. Software was developed for the reconstruction, modeling contrast kinetics using a heuristic model, display by parametric mapping and viewer/analysis of the multidimensional, high frame-rate bilateral breast images.

Abstract: A technique for correcting translational and rotational motion of an object, such as an object in a magnetic field, utilizes the k-space representation of the object. An initial region in the k-space representation is used as a motion-free reference region, indicative of the motion-free object. Motion-free data adjacent to the initial region are then estimated by extrapolating from the initial region, and the extrapolated data are subsequently used to estimate motion by correlating it with actual data. Segments adjacent to the initial region are then motion corrected and incorporated into an expanding base region. The expanded base region is used in subsequent correction steps. This process is continued until the entire k-space is motion-corrected. Two different extrapolation methods were used for the purpose of motion estimation: edge enhancement and finite-support solution. One technique is utilized near the k-space center and the other is utilized in the outer k-space regions.

Abstract: Provided is a method for rapid, 3D, dynamic, projection reconstruction bilateral breast imaging using simultaneous multi-slab volume excitation and radial acquisition of a contrast enhanced bilateral image, in conjunction with SENSE processing, using k-Space Weighted Image Contrast (“KWIC”) filtering and multi-coil arrays for signal separation in an interleaved bilateral MR bilateral breast scan that uses conventional Cartesian sampling without parallel imaging. Software was developed for the reconstruction, modeling contrast kinetics using a heuristic model, display by parametric mapping and viewer/analysis of the multidimensional, high frame-rate bilateral breast images.