Patents by Inventor Hee-Seung Lee

Hee-Seung Lee has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Anti-VAMP2 antibody for inhibiting snare complex and use thereof
    Patent number: 11958897
    Abstract: The present invention relates to an anti-VAMP2 antibody that inhibits SNARE complex and uses thereof, and more specifically, the present invention relates to an anti-VAMP2 antibody or antigen-binding fragments thereof comprising heavy and light chain CDRs of a specific sequence. The anti-VAMP2 antibody is expected to be useful for improving or treating skin wrinkles by inhibiting SNARE complex formation.
    Type: Grant
    Filed: August 14, 2019
    Date of Patent: April 16, 2024
    Assignee: HAUUL BIO
    Inventors: Hee-Jun Na, Yun-Suk Lee, Je-Ok Yoo, Kwang-Soon Lee, Kang Seung Lee, Seung Je Min
  • Beta-amino acids
    Patent number: 8772450
    Abstract: Disclosed are ?-amino acid monomers containing cylcoalkyl, cycloalkenyl, and heterocylic substituents which encompass the ? and ? carbons of the peptide backbone and ?-polypeptides made from such monomers. Method of generating combinatorial libraries of polypeptides containing the ?-peptide residues and libraries formed thereby are disclosed.
    Type: Grant
    Filed: May 3, 2012
    Date of Patent: July 8, 2014
    Assignee: Wisconsin Alumni Research Foundation
    Inventors: Samuel H. Gellman, Daniel H. Appella, Hee-Seung Lee, Paul LePlae, Emilie Porter, Xifang Wang, Matthew Woll
  • BETA-AMINO ACIDS
    Publication number: 20130023644
    Abstract: Disclosed are ?-amino acid monomers containing cylcoalkyl, cycloalkenyl, and heterocylic substituents which encompass the ? and ? carbons of the peptide backbone and ?-polypeptides made from such monomers. Method of generating combinatorial libraries of polypeptides containing the ?-peptide residues and libraries formed thereby are disclosed.
    Type: Application
    Filed: May 3, 2012
    Publication date: January 24, 2013
    Inventors: Samuel H. Gellman, Daniel H. Appella, Hee-Seung Lee, Paul LePlae, Emilie Porter, Xifang Wang, Matthew Woll
  • NOVEL METHOD FOR PREPARING PREGABALIN
    Publication number: 20100286442
    Abstract: The present invention relates to a method for preparing pregabalin ((S)-3-(aminomethyl)-5-methylhexanoic acid which is useful for the prevention and treatment of seizure disorders, pins, and psychiatric disorders. According to the present invention, pregabalin can be prepared in a high enantiomeric excess of 99% or more, without an additional step of separating or purifying its enantiomer.
    Type: Application
    Filed: August 11, 2008
    Publication date: November 11, 2010
    Applicant: KAIST
    Inventors: Hee-Seung Lee, Joohee Lee, Taedong Ok
  • Beta-amino acids
    Publication number: 20070123709
    Abstract: Disclosed are ?-amino acid monomers containing cylcoalkyl, cycloalkenyl, and heterocylic substituents which encompass the ? and ? carbons of the peptide backbone and ?-polypeptides made from such monomers. Method of generating combinatorial libraries of polypeptides containing the ?-peptide residues and libraries formed thereby are disclosed.
    Type: Application
    Filed: July 7, 2006
    Publication date: May 31, 2007
    Inventors: Samuel Gellman, Daniel Appella, Hee-Seung Lee, Paul LePlae, Emilie Porter, Xifang Wang, Matthew Woll
  • Beta-amino acids
    Publication number: 20020037997
    Abstract: Disclosed are &bgr;-amino acid monomers containing cylcoalkyl, cycloalkenyl, and heterocylic substituents which encompass the &agr; and &bgr; carbons of the peptide backbone and &bgr;-polypeptides made from such monomers. Method of generating combinatorial libraries of polypeptides containing the &bgr;-peptide residues and libraries formed thereby are disclosed.
    Type: Application
    Filed: April 11, 2001
    Publication date: March 28, 2002
    Inventors: Samuel H. Gellman, Daniel H. Appella, Hee-Seung Lee, Paul LePlae, Emilie Porter, Xifang Wang, Matthew Woll