Abstract: The present invention relates to a novel AUTOTAC chimeric compound in which a new p62 ligand and a target-binding ligand are connected by a linker, a stereoisomer, hydrate, solvate or prodrug thereof, and a pharmaceutical or food composition for the prevention or treatment of diseases by degrading the target protein including the same as an active ingredient. They can target specific proteins to adjust their concentrations, and can also deliver drugs and other small molecule compounds to lysosomes. The AUTOTAC chimeric compound according to the present invention can be usefully used as a pharmaceutical composition for the prevention, amelioration or treatment of various diseases by selectively eliminating specific proteins.

Abstract: A display device includes a first thin film transistor disposed on a substrate. A first insulating interlayer covers lire first thin film transistor. An active pattern is disposed on the first insulating interlayer. The active pattern includes indium-gallium-zinc oxide (IGZO) having a thickness in a range of about 150 ? to about 400 ?. A gate insulation layer covers the active pattern A gate pattern is disposed on the gate insulation layer. A second insulating interlayer covers the gate pattern.

Abstract: The present invention relates to a novel p62 ligand compound, a stereoisomer, hydrate, solvate or prodrug thereof, and a pharmaceutical or food composition for preventing or treating misfolded protein diseases comprising the same as an active ingredient. The p62 ligand compound according to the present invention can be usefully used as a pharmaceutical composition for the prevention, amelioration or treatment of various proteinopathies by activating selective autophagy in cells and thus selectively eliminating in vivo proteins, organelles and aggregates.

Abstract: The present disclosure relates to a novel Lactobacillus plantarum CJLP17 strain having acid resistance, bile resistance, and an immune-enhancing activity, and to a composition comprising the Lactobacillus plantarum CJLP17 strain.

Abstract: According to one or more embodiments, an organic light-emitting device includes: a first electrode; a second electrode facing the first electrode; and an organic layer between the first electrode and the second electrode, the organic layer including an emission layer, wherein the organic layer may include a first compound represented by one selected from Formulae 1-1 and 1-2, and a second compound represented by Formula 2:

Abstract: According to one or more embodiments, an organic light-emitting device includes: a first electrode; a second electrode facing the first electrode; and an organic layer between the first electrode and the second electrode, the organic layer including an emission layer, wherein the organic layer may include a first compound represented by one selected from Formulae 1-1 and 1-2, and a second compound represented by Formula 2:

Abstract: The present invention relates to an electrochemical cell having a channel-type flow-electrode unit. The channel-type flow-electrode structure according to the present invention, which has at least two channel-type flow-electrode units, can significantly reduce manufacturing costs and installation space by reducing the number of parts while extending the electrode capacity to be suitable for large-scale plants for electricity generation, energy storage, desalination, etc. In addition, the channel-type flow-electrode structure can be applied not only to a capacitive flow-electrode device and/or a redox flow battery device, but also to all of the devices for electricity generation, energy storage, and desalination while moving ions or protons.

Abstract: The present invention relates to a proton-transport vesicle and a method for preparing the same, the proton-transfer vesicle comprising: (a) a single phospholipid bilayer liposome; (b) a rhodopsin protein; and (c) a photosystem II protein, wherein the rhodopsin protein and the photosystem II protein are inserted and located in a bilayer of the liposome. Since the heterologous photosensitive proteins are inserted and located in the bilayer of the liposome, the vesicle has an absorption wavelength band of the whole region of visible light by utilizing absorption bands of different lights of the respective photosensitive proteins. Thus, the restricted efficiency caused by utilizing only a specific wavelength in existing organisms or artificial vesicles was improved, and the wavelength region can be enlarged to the all wavelength ranges of visible light.

Abstract: Disclosed is a method of manufacturing carbonized fine cellulose, which enables the formation of carbonized nano-sized cellulose by subjecting cellulose to drying, carbonization, and pulverization by means of shock waves using ultrasonic waves and microbubbles, thus realizing mass producibility, making it possible to fabricate a carbonized nano-sized material having uniform quality, and reducing the manufacturing costs. The carbonized fine cellulose is in the form of a nano-sized uniform carbon powder, and can thus be utilized as a catalyst support in various forms, such as fuel cell electrodes, electrodes of energy storage devices such as supercapacitors or secondary batteries, catalyst supports for micro-nano hybrid reactors, etc.

Abstract: Disclosed herein are porous graphene filters, each consisting of a carbon monoatomic layer having small holes formed therein during the graphene formation, a plurality of the porous graphene filters being used to selectively filter a specific material from a mixture of at least two different materials, a method for manufacturing the same, and a filtering apparatus using the same. The method comprises: separately forming a first graphene filter having a first hole of a first size and a second graphene filter having a second hole of a second size, during deposition of carbon atoms generated from a carbon source for formation of graphene, by substituting the carbon atoms, in part, with a substitution atom generated from a substitution source, the second size being larger than the first size; and arranging the first graphene filter and the second graphene filter in a filter body equipped with an inlet and an outlet.

Abstract: The present invention relates to an electrochemical cell having a channel-type flow-electrode unit. The channel-type flow-electrode structure according to the present invention, which has at least two channel-type flow-electrode units, can significantly reduce manufacturing costs and installation space by reducing the number of parts while extending the electrode capacity to be suitable for large-scale plants for electricity generation, energy storage, desalination, etc. In addition, the channel-type flow-electrode structure can be applied not only to a capacitive flow-electrode device and/or a redox flow battery device, but also to all of the devices for electricity generation, energy storage, and desalination while moving ions or protons.

Abstract: Disclosed are a large-scale composite synthesis system, a reactor therefor, and a synthesis method using the same, wherein two or more different samples are vaporized in respective vaporizers, and are then fed into a reactor that has a relatively large transverse cross-sectional diameter compared to the connector for transporting the samples in a gas phase and is maintained at a temperature lower than that of the connector, thus producing a powder composite, the composite being synthesized while being electrostatically attached to an adherend surface.

Abstract: Disclosed is a method of forming a nitrogen-doped porous graphene envelope. The method of forming the nitrogen-doped porous graphene envelope includes dissolving a nitrogen precursor in an organic precursor and then vaporizing the resulting precursor to thus simultaneously synthesize the graphene envelope and perform nitrogen doping in a single step.

Abstract: The present disclosure relates to a metal-organic framework and a method for preparing the same. In accordance with the present disclosure, a metal-organic framework having large specific surface area can be prepared and the prepared porous material exhibits high carbon dioxide and carbon monoxide adsorption characteristics at room temperature.

Abstract: Disclosed are a porous graphene member having through-holes formed therein, a method for manufacturing the porous graphene member, and an apparatus for manufacturing the porous graphene member using the method. The method comprises: introducing a carbon source and a substitution reaction source into a deposition furnace; thermally decomposing the carbon source and the substitution reaction source simultaneously to generate carbon atoms and substitution atoms, respectively, wherein the carbon atoms are deposited on a substrate present within the deposition furnace to form a graphene film consisting of a monoatomic layer structure, and during the deposition of carbon atoms, the substitution atoms not only interfere with covalent bonds between the carbon atoms to cause crystal defects, but also substitute for parts of the carbon atoms to in situ form through-holes in the graphene, thereby creating the porous graphene member; and releasing the porous graphene member from the substrate.

Abstract: The present invention relates to a proton-transport vesicle and a method for preparing the same, the proton-transfer vesicle comprising: (a) a single phospholipid bilayer liposome; (b) a rhodopsin protein; and (c) a photosystem II protein, wherein the rhodopsin protein and the photosystem II protein are inserted and located in a bilayer of the liposome. Since the heterologous photosensitive proteins are inserted and located in the bilayer of the liposome, the vesicle has an absorption wavelength band of the whole region of visible light by utilizing absorption bands of different lights of the respective photosensitive proteins. Thus, the restricted efficiency caused by utilizing only a specific wavelength in existing organisms or artificial vesicles was improved, and the wavelength region can be enlarged to the all wavelength ranges of visible light.

Abstract: Disclosed herein is a method of preparing an alloy catalyst for fuel cells, which is suitable for mass production and can reduce manufacturing costs. The method includes vaporizing at least two catalyst precursors in separate vaporizers; supplying the at least two vaporized catalyst precursors to a reactor while preventing contact therebetween; and synthesizing an alloy catalyst in the reactor. The method can prepare an alloy catalyst through a one-step process unlike typical multi-step methods for preparing catalysts, and can prepare an alloy catalyst at a much lower temperature than the typical methods for preparing alloys, thereby enabling mass production and cost reduction.

Abstract: Provided are a carbon electrode particularly suitable to be used as a negative electrode of an energy storing apparatus and the like and a method for manufacturing the same by forming the carbon electrode by heat-treating a natural carbon material such as a natural fiber sheet including a natural fiber or cellulose sheet including a natural cellulose fiber which is a natural material other than a petroleum-based material or a petroleum-based synthetic material to reduce manufacturing cost, shorten a manufacturing process, minimize discharge of a hazardous substance, and uniformly maintain storage capacitance even in repeated charging and discharging when being applied to the energy storing apparatus. The carbon electrode includes any one of an alkaline metal particle and an alkaline earth metal particle having an average particle size of less than 100 nm which is formed on a surface in a process of carbonizing a natural carbon material.

Abstract: Disclosed are a metal-carbon hybrid composite having a nitrogen-doped carbon surface and a method of manufacturing the same. More particularly, the present invention relates to a method of manufacturing a metal-carbon hybrid composite, wherein the surface of carbon for the metal-carbon hybrid composite may be doped with nitrogen in a single step using a co-vaporization process, and to a metal-carbon hybrid composite having a nitrogen-doped carbon surface manufactured by the method.

Abstract: According to one or more embodiments, an organic light-emitting device includes: a first electrode; a second electrode facing the first electrode; and an organic layer between the first electrode and the second electrode, the organic layer including an emission layer, wherein the organic layer may include a first compound represented by one selected from Formulae 1-1 and 1-2, and a second compound represented by Formula 2: