Abstract: The invention is directed to a vaccine comprising: i) coxsackie B virus CBV1 and CBV2, and ii) at least one coxsackie B virus selected from CBV3, CBV4, CBV5 and CBV6. The CBVs are present in the vaccine in inactivated form, in the form of a component of the virus or as an antibody against the virus. The vaccine is effective in preventing and treating type 1 diabetes. So is an anti-coxsackie B virus composition provided.

Abstract: The invention discloses an immunomodulatory composition comprising non-culturable bacteria, a method of production and an article and an apparatus for its use and administration.

Abstract: The invention discloses an immunomodulatory composition comprising non-culturable bacteria, a method of production and an article and an apparatus for its use and administration.

Abstract: The invention discloses an immunomodulatory composition comprising non-culturable bacteria, a method of production and an article and an apparatus for its use and administration.

Abstract: The invention discloses an immunomodulatory composition comprising non-culturable bacteria, a method of production and an article and an apparatus for its use and administration.

Abstract: A method and apparatus are provided for facilitating remote participance in a community. A method may include causing an anchor terminal located at a first location to use a proximity-based wireless communication technology to participate in an ad hoc community formed at least in part by the anchor terminal and one or more further terminals at the first location using the proximity-based wireless communication technology to communicate with each other. The method may further include causing the anchor terminal to maintain a connection to a structured network, thereby enabling a remote terminal to participate in the community. The method may additionally include, in an instance in which the remote terminal participates in the community, causing the anchor terminal to serve as a gateway between the terminals participating in the community at the first location and the remote terminal. A corresponding apparatus is also provided.

Abstract: A method and apparatus are provided for facilitating remote participance in a community. A method may include determining, at a network node accessible via a structured network, a community identifier for an ad hoc community formed at least in part by a plurality of terminals at a first location using a proximity-based wireless communication technology to communicate with each other. The method may further include causing storage at the network node of the determined community identifier and associated membership information for the community. The membership information may include contact information associated with at least one of the plurality of terminals 10. A corresponding apparatus is also provided.

Abstract: A method and apparatus are provided for facilitating remote participance in a community. A method may include causing an anchor terminal located at a first location to use a proximity-based wireless communication technology to participate in an ad hoc community formed at least in part by the anchor terminal and one or more further terminals at the first location using the proximity-based wireless communication technology to communicate with each other. The method may further include causing the anchor terminal to maintain a connection to a structured network, thereby enabling a remote terminal to participate in the community. The method may additionally include, in an instance in which the remote terminal participates in the community, causing the anchor terminal to serve as a gateway between the terminals participating in the community at the first location and the remote terminal. A corresponding apparatus is also provided.

Abstract: Two circularly permuted avidin monomers arc designed. The circularly permuted monomers are fused and the resulting fusion peptides (dcAvd) form a pseudo-tetrameric dual-chain avidin, which is biologically active in biotin binding and shows similar structural characteristics as wild-type avidin. The dcAvd makes the development of dual-affinity avidins possible by allowing the adjustment of the ligand binding properties in the half of the binding sites differently than in the rest of the sites. The present invention provides further a single-chain avidin (scAvd) where two dcAvd-molecules are fused together via a linker to form a single polypeptide with four binding sites for biotin or other ligand.

Abstract: Two circularly permuted avidin monomers are designed. The circularly permuted monomers (cpAvd5?4 and cpAvd6?5) are fused and the resulting fusion peptides (dcAvd) form a pseudo-tetrameric dual-chain avidin, which is biologically active in biotin binding and shows similar structural characteristics as wild-type avidin. The dcAvd makes the development of dual-affinity avidins possible by allowing the adjustment of the ligand binding properties in the half of the binding sites differently than in the rest of the sites. The present invention provides further a single-chain avidin (scAvd) where two dcAvd-molecules are fused together via a linker to form a single polypeptide with four binding sites for biotin.

Abstract: The present invention relates to new chimeric mutants of avidin protein with improved properties, e.g. thermostability, better stability against proteolysis, better charge properties (for example lower pl) compared to native avidin and avidin-related proteins, AVRs. The chimeric avidin mutants comprise mutants where a region or regions in avidin are substituted by a corresponding region or regions from an AVR protein.

Abstract: Turbulence generator for the head box of a paper machine, the quality of the surface of the flow ducts of which has been improved and the manufacturing technique of which is simple. The turbulence generator according to the invention is characterized by the feature that the body of the perforated beams (6a, 6b) and the coating material of the face surfaces and the flow ducts are densely and tightly bonded to each other and that the coating materials of the flow ducts (7) is both physically and chemically wear resistant. The body of the beam is plastic, and the surfaces of the flow ducts have a ceramic coating on them.

Abstract: Equipment for loading an exchange platform onto a vehicle includes a rear frame pivotally mounted to the rear of the vehicle and a middle frame pivotally mounted on the rear frame. An angle piece has a horizontal portion pivotally mounted to the middle frame and a vertical portion with a grasping device at its upper end. A cylinder for operating the loading equipment is connected between the vehicle and the middle frame. In addition, a link arm and/or a second cylinder is provided between the vehicle and either the rear or middle frames to enable the exchange platform to be raised above the vehicle in a horizontal position.

Abstract: Loading equipment which is suitable for loading exchange platforms of two different platform frame widths onto a truck chassis or dumper frame and for unloading the exchange platforms from same. The loading equipment comprises a locking mechanism for securing the exchange platform onto the frame of the loading equipment automatically in connection with the pulling-on step of the exchange platform. The rollers at the rear end of the truck are wide enough that the inner ends of the rollers are suitable for a rolling base of the frame beams of exchange platforms with narrow platform frame width and the outer ends of the rollers are suitable for a rolling base of the frame beams of exchange platforms with wide platform frame width. The platform locking mechanism of the loading equipment is located in the center planes perpendicular to the rolling surfaces, i.e.

Abstract: Apparatus for loading a container onto a truck or trailer, and for dumping the container, includes a first frame pivotally attached to the rear of the truck or trailer and a second frame pivotally mounted on the first frame. An L-shaped member is pivotally mounted on the second frame, and its pivotal movement is controlled independently of the pivotal movement of the two frames by a piston and cylinder arrangement. The path of movement of the grasping end of the L-shaped member is twice the length of the section of the member that is connected to the second frame, to enable different sized containers to be transported and dumped in different positions on the truck or trailer.