Patents by Inventor Heinrich Kladders
Heinrich Kladders has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20240108822Abstract: A nebulizer for nebulizing a liquid includes: a container containing multiple doses of the liquid, a housing part for receiving the container, where the container is moveable in an axial stroke within the housing part for withdrawing a dose of the liquid from the container and pressurizing the respective dose for nebulization; and an indicator device for counting or indicating a number of uses performed or still possible with the container, where the indicator device includes an indicator element and an actuator for actuating and/or stepwise moving the indicator element directly, and where the indicator element is rotatably and inseparately connected to the container or a casing (20) thereof and configured to move axially together with the container, and the actuator is rigidly connected to the housing part.Type: ApplicationFiled: December 14, 2023Publication date: April 4, 2024Applicant: Boehringer lngelheim International GmbHInventors: Heinrich KLADDERS, Thomas WABNITZ, Herbert GRAESSL, Andree JUNG, Gilbert WUTTKE
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Patent number: 10973997Abstract: A nebulizer for nebulizing a liquid from a container is proposed. The nebulizer comprises a liquid pump for withdrawing the liquid in doses from the container and pressurizing the respective doses for nebulization. The nebulizer comprises in addition an air pump for temporarily pressurizing the liquid in the container to help withdrawing the liquid from a collapsible bag in the container.Type: GrantFiled: January 20, 2017Date of Patent: April 13, 2021Assignee: BOEHRINGER INGELHEIM INTERNATIONAL GMBHInventors: Heinrich Kladders, Matthias Hausmann
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Publication number: 20200215275Abstract: A nebulizer for nebulizing a liquid from a container includes a fluid pump for withdrawing the liquid in doses from the container and pressurizing the respective doses for nebulization. The nebulizer includes in addition an air pump with a piston/cylinder arrangement for pumping air into the container to pressurize the liquid in the container to help withdrawing the liquid from the container.Type: ApplicationFiled: July 23, 2018Publication date: July 9, 2020Applicant: Boehringer lngelheim International GmbHInventors: Heinrich KLADDERS, Thomas WABNITZ, Herbert GRAESSL, Andree JUNG, Gilbert WUTTKE
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Publication number: 20200179620Abstract: A nebulizer for nebulizing a liquid from a container, where the nebulizer includes a fluid pump for withdrawing the liquid in doses from the container and pressurizing the respective doses for nebulization. The container includes an air pump with a piston/cylinder arrangement to pressurizing the liquid in the container to help withdrawing the liquid from the container. A control valve limits the air pressure acting on the liquid.Type: ApplicationFiled: July 23, 2018Publication date: June 11, 2020Applicant: Boehringer lngelheim International GmbHInventors: Gilbert WUTTKE, Herbert GRAESSL, Heinrich KLADDERS
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Patent number: 10220165Abstract: The invention relates to a capsule for receiving a preferably powdered pharmaceutical preparation and an inhaler in which, for inhalation, the preparation is expelled from the capsule through at least one hole. A capsule according to the invention comprises as capsule elements a capsule cap and a capsule body, at least one of which comprises at least one prefabricated hole. Systems according to the invention comprising inhalers and capsules are described, in which the prefabricated hole in the capsule is sealed off in the transporting state of the system and is open in the usage state. The hole is exposed by actuation of a pushing or pulling mechanism. Prior to this the hole is closed off by part of the capsule itself or by a capsule receptacle belonging to the inhaler. In one embodiment the capsule may be present in two different states, for example in different insertion positions of the capsule elements. In the first state the prefabricated hole is closed off and in the second it is exposed.Type: GrantFiled: May 21, 2012Date of Patent: March 5, 2019Assignee: Boehringer Ingelheim International GmbHInventors: Stephen Terence Dunne, Jens Besseler, Jessica Frentzel-Beyme, Holger Holakovsky, Heinrich Kladders, Claudius Weiler, Ole Zumblick
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Publication number: 20170209892Abstract: A nebulizer for nebulizing a liquid from a container is proposed. The nebulizer comprises a liquid pump for withdrawing the liquid in doses from the container and pressurizing the respective doses for nebulization. The nebulizer comprises in addition an air pump for temporarily pressurizing the liquid in the container to help withdrawing the liquid from a collapsible bag in the container.Type: ApplicationFiled: January 20, 2017Publication date: July 27, 2017Applicant: Boehringer Ingelheim International GmbHInventors: Heinrich KLADDERS, Matthias HAUSMANN
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Patent number: 9364841Abstract: An inhaler including a pre-inserted cartridge (100) is proposed. The cartridge contains liquid (103) which is preferably pressurized to a low pressure. The cartridge is connected via an aerosol valve (106) with the inhaler. The liquid is further pressurized by a pump (117) of the inhaler to a high pressure and atomized.Type: GrantFiled: February 18, 2009Date of Patent: June 14, 2016Assignee: BOEHRINGER INGELHEIM PHARMA GMBH & CO. KGInventors: Stephen T. Dunne, Heinrich Kladders
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Patent number: 8905017Abstract: A reservoir and a nebulizer having such a reservoir are proposed. The reservoir comprises a closure for a fluid chamber with a medicament formulation that is formed by two closure members welded together. The closure comprises a particle barrier for preventing the ingress into the fluid chamber of any weld particles that may potentially be formed during the welding of the two closure members. The fluid chamber is preferably broadened in the shape of a beaver tail and is sealed lengthways with an additional strip of material.Type: GrantFiled: March 12, 2010Date of Patent: December 9, 2014Assignee: Boehringer Ingelheim International GmbHInventors: Matthias Hausmann, Carsten Henning, Heinrich Kladders
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Publication number: 20140182587Abstract: The invention relates to a capsule for receiving a preferably powdered pharmaceutical preparation and an inhaler in which, for inhalation, the preparation is expelled from the capsule through at least one hole. A capsule according to the invention comprises as capsule elements a capsule cap and a capsule body, at least one of which comprises at least one prefabricated hole. Systems according to the invention comprising inhalers and capsules are described, in which the prefabricated hole in the capsule is sealed off in the transporting state of the system and is open in the usage state. The hole is exposed by actuation of a pushing or pulling mechanism. Prior to this the hole is closed off by part of the capsule itself or by a capsule receptacle belonging to the inhaler. In one embodiment the capsule may be present in two different states, for example in different insertion positions of the capsule elements. In the first state the prefabricated hole is closed off and in the second it is exposed.Type: ApplicationFiled: May 21, 2012Publication date: July 3, 2014Applicant: Boehringer Ingelheim international GmbHInventors: Stephen Terence Dunne, Jens Besseler, Jessica Frentzel-Beyme, Holger Holakovsky, Heinrich Kladders, Claudius Weiler, Ole Zumblick
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Patent number: 8584669Abstract: An inhaler (1) is proposed (see FIG. 1), for the inhalation of a formulation (2) from capsules (3) that each contain one dose of the formulation. The capsules are preferably each emptied in a capsule chamber (4) by being set in motion by a stream of air flowing through the capsule chamber. The stream of air can be generated by the inhalation of a user or patient and/or can be generated actively generated by the inhaler. For simple handling, the inhaler has a means for, in particular, automatic filling, emptying and/or cleaning of the capsule chamber, if the latter is used more than once. Alternatively, the inhaler has a large number of capsule chambers that each preferably already contain a capsule and re preferably used just once.Type: GrantFiled: April 11, 2007Date of Patent: November 19, 2013Assignee: Boehringer Ingelheim International GmbHInventors: Jens Besseler, Hubert Kunze, Achim Moser, Ralf Thoemmes, Gilbert Wuttke, Dieter Hochrainer, Heinrich Kladders, Christoph Dworzak, Josef Eckert, Antonio Lanci, Markus Mast, Elmar Mock, Andre Klopfenstein
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Patent number: 8539947Abstract: An inhaler for inhaling powdered medicaments from capsules, having: a lower part which is cup-shaped, a plate latched to the lower part to close off the lower part, a capsule holder arranged on the underside of the plate, a mouthpiece that can be latched to the top of plate, and an actuating member for interacting with at least one pin for piercing a capsule in the capsule holder, where the actuating member includes a larger outer actuating member and a smaller inner actuating member, the outer actuating member forms a user-operated push-button, the inner actuating member contacts and holds the pin below a suspension element of the outer actuating member from the plate, and the point of application of force by the user onto push-button is lower than the inner actuating member.Type: GrantFiled: July 17, 2008Date of Patent: September 24, 2013Assignee: Boehringer Ingelheim International GmbHInventors: Rolf Kuhn, Burkhard Peter Metzger, Torsten Kuehn, Heinrich Kladders, Joern-Eric Schulz
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Patent number: 8528548Abstract: An inhaler (1) is proposed for inhaling a preparation (2) from a carrier (3) and/or through a delivery channel (16) as depicted in exemplary FIG. 1. The carrier or delivery channel is preferably flexible, flat, band-shaped, strip-shaped, thread-like, blister-like and/or film-like and can be set in vibration by a stream of air (5). The carrier or delivery channel is preferably set in vibration by a separate element (6), which for its part is set in motion or vibration by the stream of air. Alternatively, or in addition, the inhaler has a pump (10) with a telescopic pump chamber (20) for generating a stream of air for expelling and/or dispersing a preparation.Type: GrantFiled: August 17, 2007Date of Patent: September 10, 2013Assignee: Boehringer Ingelheim International GmbHInventor: Heinrich Kladders
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Patent number: 8205613Abstract: A preferably pulverulent formulation to be dosed is received in a dosing chamber having a partly gas-permeable wall. The introduction and discharge of the formulation is achieved by means of a pumping device that alternately generates a negative pressure and an excess pressure in the dosing chamber. The dosing chamber can also be displaced between a receiving position and a discharge position by means of a piston, the piston controlling the negative and excess pressure in the dosing chamber. Furthermore, the size of the dosing chamber is adjustable.Type: GrantFiled: August 17, 2007Date of Patent: June 26, 2012Assignee: Boehringer Ingelheim International GmbHInventor: Heinrich Kladders
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Publication number: 20120132198Abstract: A reservoir and a nebuliser having such a reservoir are proposed. The reservoir comprises a closure for a fluid chamber with a medicament formulation that is formed by two closure members welded together. The closure comprises a particle barrier for preventing the ingress into the fluid chamber of any weld particles that may potentially be formed during the welding of the two closure members. The fluid chamber is preferably broadened in the shape of a beaver tail and is sealed lengthways with an additional strip of material.Type: ApplicationFiled: March 12, 2010Publication date: May 31, 2012Applicant: BOEHRINGER INGELHEIM INTERNATIONAL GMBHInventors: Matthias Hausmann, Carsten Henning, Heinrich Kladders
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Patent number: 8001965Abstract: The invention relates to a novel capsule for receiving an active substance to be administered by inhalation, which is preferably intended for use in a powder inhaler operating on the Bernoulli principle.Type: GrantFiled: February 4, 2009Date of Patent: August 23, 2011Assignee: Boehringer Ingelheim International GmbHInventors: Heinrich Kladders, Burkhard Metzger, Dieter Hochrainer
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Publication number: 20110168175Abstract: An inhaler including a pre-inserted cartridge (100) is proposed. The cartridge contains liquid (103) which is preferably pressurized to a low pressure. The cartridge is connected via an aerosol valve (106) with the inhaler. The liquid is further pressurized by a pump (117) of the inhaler to a high pressure and atomized.Type: ApplicationFiled: February 18, 2009Publication date: July 14, 2011Applicant: BOEHRINGER INGELHEIM PHARMA GMBH & CO. KGInventors: Stephen T. Dunne, Heinrich Kladders
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Patent number: 7963955Abstract: Foil bags are used as a primary packaging for liquids, the bags permitting the liquid to be taken therefrom without the application of a considerable amount of force. A container is provided for a medicinal liquid, the container being gas-tight and liquid-tight so that it is storable over many months. The container includes a collapsible foil bag on which a flange, which is stable in respect of shape, is disposed. The flange is designed for fitting onto a discharge connection member. The container can be disposed in a casing which is stable in respect of shape. The medicinal liquid does not come into contact with air and is protected from the effect of light. The medicinal liquid may be dispensed from the foil bag in many partial quantities over a prolonged period of time, with a respective partial amount thereof being converted into an aerosol by means of an atomizer.Type: GrantFiled: January 12, 2004Date of Patent: June 21, 2011Assignee: Boehringer Ingelheim International GmbHInventors: Bernhard Freund, Dieter Hochrainer, Heinrich Kladders, Bernd Zierenberg, Joachim Eicher, Johannes Geser, Martin Essing, Holger Reinecke
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Patent number: 7950388Abstract: A nebuliser and a container in each case with an aeration device are proposed, the aeration device being designed for the direct aeration of a liquid space in the container. The container comprises a rigid, gas-tight outer case and a closure, which is opened by connecting or inserting a delivery element. A long storage life and long service life with low loss of fluid or solvent are thereby provided in the form of a simple and inexpensive construction.Type: GrantFiled: June 26, 2006Date of Patent: May 31, 2011Assignee: Boehringer Ingelheim International GmbHInventors: Hubert Kunze, Matthias Hausmann, Jens Besseler, Carsten Henning, Heinrich Kladders, Florian Witte, Johannes Geser, Markus Mast, Antonino Lanci, Christoph Dworzak, Elmar Mock
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Patent number: 7878193Abstract: The invention relates to a novel capsule for receiving an active substance to be administered by inhalation, which is preferably intended for use in a powder inhaler operating on the Bernoulli principle.Type: GrantFiled: January 14, 2004Date of Patent: February 1, 2011Assignee: Boehringer Ingelheim International GmbHInventors: Heinrich Kladders, Burkhard Metzger, Dieter Hochrainer
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Publication number: 20100275917Abstract: The present invention relates to a method, a device, and a control program for the fluid-tight sealing of capsules containing medicaments, wherein the capsules consist of at least one capsule body and a capsule cap which are set one into the other telescopically and provided with a tight band in the abutment region on the exterior side of the capsule, wherein the capsule components are filled with gas which has a changed temperature and/or a changed pressure in relation to the environment, and wherein a reduction of the difference in pressure in the capsule occurs via gaps between capsule body and capsule cap after the capsule components have been placed one inside the other. The capsules produced via the method according to the invention are disposable capsules and preferably contain a single dose of an orally administered pharmaceutical formulation in the form of a powder or a liquid.Type: ApplicationFiled: July 17, 2008Publication date: November 4, 2010Applicant: BOEHRINGER INGELHEIM INTERNATIONAL GMBHInventors: Rolf Kuhn, Burkhard Peter Metzger, Torsten Kuehn, Heinrich Kladders, Joern-Eric Schulz