Patents by Inventor Heinrich Kochling

Heinrich Kochling has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Matrix-bearing targets for maldi mass spectrometry and methods of production thereof
    Patent number: 5770272
    Abstract: The present invention provides new methods for producing substantially continuous, homogeneous layers of MALDI matrix materials deposited on MALDI targets and substantially free of voids and large crystals. The methods involve the deposition of MALDI matrix materials in a nebulized spray which is enveloped in a sheath of non-reactive gas which confines and entrains the spray and aids in the evaporation of the solvent such that substantial, if not complete, solvent evaporation occurs before the matrix material is deposited on the target surface. The invention further provides such matrix layers and pre-formed matrix-bearing targets for use in MALDI mass spectrometry.
    Type: Grant
    Filed: April 28, 1995
    Date of Patent: June 23, 1998
    Assignee: Massachusetts Institute of Technology
    Inventors: Klaus Biemann, Heinrich Kochling