Patents by Inventor Heinrich Schostarez

Heinrich Schostarez has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Aza hydroxylated ethyl amine compounds
    Publication number: 20060069264
    Abstract: Disclosed are compounds of formula: and pharmaceutically acceptable salts and esters thereof, useful in treating and/or preventing Alzheimer's disease and other similar diseases, wherein RN, RC, R1, R2 and R20 are defined herein. These compounds include inhibitors of the beta-secretase enzyme that are useful in the treatment of Alzheimer's disease and other diseases characterized by deposition of A beta peptide in a mammal. The compounds of the invention are useful in pharmaceutical compositions and methods of treatment to reduce A beta peptide formation.
    Type: Application
    Filed: November 1, 2005
    Publication date: March 30, 2006
    Inventors: Heinrich Schostarez, Robert Chrusciel, Rebecca Centko
  • Aza hydroxylated ethyl amine compounds
    Patent number: 6960664
    Abstract: Disclosed are compounds of formula: and pharmaceutically acceptable salts and esters thereof, useful in treating and/or preventing Alzheimer's disease and other similar diseases, wherein RN, RC, R1, R2 and R20 are defined herein. These compounds include inhibitors of the beta-secretase enzyme that are useful in the treatment of Alzheimer's disease and other diseases characterized by deposition of A beta peptide in a mammal. The compounds of the invention are useful in pharmaceutical compositions and methods of treatment to reduce A beta peptide formation.
    Type: Grant
    Filed: May 22, 2002
    Date of Patent: November 1, 2005
    Assignee: Pharmacia & UpJohn Company
    Inventors: Heinrich Schostarez, Robert Alan Chrusciel, Rebecca S. Centko
  • Statine derivatives for the treatment of Alzheimer's disease
    Publication number: 20050165069
    Abstract: The present invention relates to compounds of formula (I): useful in treating Alzheimer's disease and other similar diseases. These compounds include inhibitors of the beta-secretase enzyme that are useful in the treatment of Alzheimer's disease and other diseases characterized by deposition of A beta peptide in a mammal. The compounds of the invention are useful in pharmaceutical compositions and methods of treatment to reduce A beta peptide formation.
    Type: Application
    Filed: March 8, 2005
    Publication date: July 28, 2005
    Inventors: Heinrich Schostarez, Robert Chrusciel
  • Statine derivatives for the treatment of Alzheimer's disease
    Publication number: 20050159459
    Abstract: The present invention relates to compounds of formula (I): useful in treating Alzheimer's disease and other similar diseases. These compounds include inhibitors of the beta-secretase enzyme that are useful in the treatment of Alzheimer's disease and other diseases characterized by deposition of A beta peptide in a mammal. The compounds of the invention are useful in pharmaceutical compositions and methods of treatment to reduce A beta peptide formation.
    Type: Application
    Filed: March 8, 2005
    Publication date: July 21, 2005
    Inventors: Heinrich Schostarez, Robert Chrusciel
  • Methods of treating alzheimer's disease
    Publication number: 20050130941
    Abstract: Disclosed are methods for treating Alzheimer's disease, and other diseases, and/or inhibiting beta-secretase enzyme, and/or inhibiting deposition of A beta peptide in a mammal, by use of hydrazine compounds of formula (I) wherein the variables R1-R9 are defined herein.
    Type: Application
    Filed: June 7, 2002
    Publication date: June 16, 2005
    Inventors: Heinrich Schostarez, Robert Chrusciel
  • Amino diols useful in the treatment of alzheimer's disease
    Publication number: 20050080141
    Abstract: The present invention relates to the treatment of Alzheimer's disease and other similar diseases, and more specifically to the use of compounds that inhibit beta-secretase, an enzyme that cleaves amyloid precursor protein to produce A beta peptide, a major component of the amyloid plaques found in the brains of Alzheimer's sufferers, in such methods.
    Type: Application
    Filed: November 19, 2002
    Publication date: April 14, 2005
    Inventors: Heinrich Schostarez, Gunnar Hanson
  • Aza hydroxylated ethyl amine compounds utility
    Publication number: 20030229138
    Abstract: Disclosed are compounds of formula: 1
    Type: Application
    Filed: May 22, 2002
    Publication date: December 11, 2003
    Inventors: Heinrich Schostarez, Robert Alan Chrusciel, Rebecca S. Centko